Publications
A) List of Research Publications (Total Impact Factor 314.20)
Books / Chapters
1) Zaheer Ul-Haq and Angela K Wilson, (2020), Frontiers in Computational Chemistry, Vol-5, Bentham Science Publishers, Amsterdam. ISBN: 978-981-14-5777-7.
2) Zaheer Ul-Haq and Angela K Wilson, (2018), Frontiers in Computational Chemistry, Vol-4, Bentham Science Publishers, Amsterdam. ISBN: 978-1-68108-442-8.
3) Zaheer Ul-Haq and J. D. Madura, (2017), Frontiers in Computational Chemistry, Vol-3, Bentham Science Publishers, Amsterdam. ISBN: 978-1-68108-168-7.
4) Zaheer Ul-Haq and J. D. Madura, (2015), Frontiers in Computational Chemistry, Vol-2, Bentham Science Publishers, Amsterdam. ISBN: 978-1-60805-979-9.
5) Zaheer Ul-Haq and J. D. Madura, (2015), Frontiers in Computational Chemistry, Vol-1, Bentham Science Publishers, Amsterdam. ISBN: 978-1-60805-865-5.
6) Zaheer Ul-Haq and Reaz Uddin (2011). Structure Based 3D-QSAR Studies on Cholinesterase Inhibitors, Alzheimer’s Disease Pathogenesis-Core Concepts, Shifting Paradigms and Therapeutic Targets, Suzanne De La Monte (Ed.), ISBN: 978-953-307-690-4, InTech.
7) Reaz Uddin, Zaheer Ul-Haq, Pavel A Petukhov (2011). In Silico Modeling and Its Applications on Biomolecules, ISBN:- 3844328238, 9783844328233, LAP Lambert Academic Publishing
8) Khuram Shahzad, Asifa Ahmed, Zaheer Ul-Haq (2010). Protein Structure Prediction and Molecular Dynamics Simulation, ISBN:- 3639300270, 9783639300277, VDM Verlag Dr. Mueller.
List of Patents
1) In-Silico Based Techniques in The Identification of Potent ß-Glucoronidase Inhibitors, Yousuf M. Ul-Haq Z, Shaikh NN, Choudhary MI, US Patent 20170009272/2017.
2) Myrtocomuloacetalone 1 As an Anti Inflammatory Agent, Mesaik MA, Soomro S, Shaheen F, Khan N, Ul-Haq Z, Halim S, Choudhary MI, US Patent 9701690B2/2017.
3) Immunosuppressive Compounds, Mesaik MA, Khan KM, Abdalla OM, Rahim F, Khalid AS, Ul-Haq Z, Perveen S, Soomro S, Halim SA, US Patent 20140378515/2014.
4) Antiinflammatory Compound, Ullah S, Khan S, Mesaik MA, Ul-Haq Z, Jabeen A, Halim SA, Choudhary MI, US Patent 8329678/2012.
Submitted
Ul-Haq Z, Ashraf S, Exploration of Structural Requirements of Acylureidoindolin Derivatives by Multiplex Theoretical Approach, Scientific Reports
Teerapol Srichana, Pornvichai Temboot, Sunisa Kaewpiboon, Kittiya Tinpun, Titpawan Nakpeng, Ruqaiya Khalil, Ul-Haq Z, Visanu Thamlikitkul, PhD; Surapee Tiengrim, PhD; Physiochemical properties, molecular docking, ex vivo pharmacokinetics, and in vitro efficacy of polymyxin B nanomicelles, International Journal of Pharmaceutics
Ashraf J, Ahmad J, Ul-Haq Z, Investigating the effect of mutation on Structure Stability of m-calpain, J. Mol. Graph. Mod.
Halim SA, Khan A, Khan R, Kaleem A, Wadood A, Ul-Haq Z, Naeem S, Hussain J, Al-Harrasi A, Discovering Inhibitors of Soluble Tumor Necrosis Factor-α: An Application to Hinder TNF-α/TNFR Interaction by Computational Methods Frontiers in Immunology
Yıldız Uygun Cebeci; Hacer Bayrak, Neslihan Demirbaş; Naz S; Ahmet Demirbaş; UL-Haq Z, Conazole Analogues and Mannich Reactions of 1,2,4-Triazole derivatives containing Cinnamic functional group and prediction of Antimicrobial Activities by using in-silico techniques, Medicinal Chemistry Research
Aqsa Shaheen, Moazur Rahman, Ul-Haq Z, Functional and structural characteristics of the MdtM transporter from Salmonella Typhi, Applied Microbiology and Biotechnology
Ali A, Rasheed A, Ul-Haq Z, Naz S, Kumar A, Kumar N, Park J, Rafiq M, Rhee M, Al-Khedhairy A, Masur K, Attri1 P, Lee K, Choi1 EH, Plasma activated solution enhances melanogenesis through increasing reactive oxygen and nitrogen species, Scientific Reports.
Syeda Sadia Fatima, Abidi SH, Saeed M, Ali A, Khalid E, Chaudhry B, Khan TA, Ul-Haq Z, Chemerin Profile of Human Breast Milk Structural Prediction and Dynamic Behavior of Protein-Protein Interactions with Chemokine like Receptor-1(CMKLR1)
Ul-Haq Z, Khalil R, Mehmood U, Aboudi A. Biological Evaluation and In Sillico investigation of Cholinesterase inhibitory potential of Triazole derivatives.
2019
Ullah S, Mirza S, Uzma Salar, Hussain S, Javaid K, Khan KM, Ruqaiya Khalil, Wahab A, Ul-Haq Z, Perveen S, Choudhary MI, 2-Mercapto Benzothiazole Derivatives: As Potential Leads for the Diabetic Management. Med. Chem. 2019 Jun 12. doi: 10.2174/1573406415666190612153150 .
Abu-Aisheh MN, Al-Aboudi A, Mustafa MS, El-Abadelah MM, Ali SY, Ul-Haq Z, Mubarak MS, Coumarine derivatives as antiacetylcholinestrase (AChE) and butyrylcholinestrase (BChE) inhibitors, an in vitro, molecular docking and molecular dynamics simulations study Heliyon, 5, 1-20
Mohammed IA, Akhtar MN, Biau FJ, Tor YS, Zareen S, Shahabudin SB, Hamid HBA, Ul-Haq Z, Khalil R, Khalaf RM, Isolation of Cardamonin and Pinostrobin Chalcone from the Rhizomes of Boesenbergia rotunda (L.) Mansf. and their Cytotoxic Effects on H-29 and MDA-MB-231 Cancer Cell Lines, The Natural Products Journal, 10.2174/2210315509666190117151542
Ghani U, Alharbi A, Nur-e-Alam M, Yousaf M, Ul-Haq Z, Natural flavonoid a-glucosidase inhibitors from Retama raetam: enzyme inhibition and molecular docking reveal important interactions with the a-glucosidase active site, Bioorganic Chemistry.
Khan N, Halim SA, Khan W, Zafar SK, Ul-Haq Z, In-silico Designing and Characterization of Binding Modes of Two Novel Inhibitors for CB1 Receptor Against Obesity by Classical 3D-QSAR Approach, J. Mol. Graph Mod. (Accepted)
Shah MA, Reanmongkol W, Radenahmad N, Khalil R, Ul-Haq Z, Panichayupakaranant P, Anti-hyperglycemic and anti-hyperlipidemic effects of rhinacanthins-rich extract from Rhinacanthus nasutus leaves in nicotinamide-streptozotocin induced diabetic rats, Biomed. Pharmacother. 113:108702.
Nazeer M, Waheed H, Saeed M, Ali SY, Choudhary MI, Ul-Haq Z, Ahmed A, Purification and Characterization of a Nonspecific Lipid Transfer Protein 1 (nsLTP1) from Ajwain (Trachyspermum ammi) Seeds, Scientific Reports, 9;4148.
Naz S, Baigg N, Khalil R, Ul-Haq Z, Characterization of cryptic allosteric site at IL-4Rα: New paradigm towards IL-4/IL-4R inhibition, Int J Biol Macromol. 123:239-45.
For complete list of publication please click here
B) Abstracts in Scientific Meetings:
2007
23) Zaheer-ul-Haq and Reaz Uddin, 3D-QSAR Study of Steroidal Alkaloid Analogues as Inhibitors of Butyrylcholinesterase, 233rd ACS National Meeting, held in Chicago, IL, March 25-28.
22) Zaheer-ul-Haq and Sobia Ahsan, Modeling Aided Lead Design of Cytokine Inhibitors, 1st International Workshop-cum-Training Course on Molecular Medicine and Drug Research held in Dr. Panjwani Center For Molecular Medicine & Drug Research, University Of Karachi, on January 16-30.
21) Zaheer-ul-Haq and Abdul-Wadood, Prediction of Binding Affinities for Hydroxamic Acid Derivatives as Urease Inhibitors by Molecular Docking and 3D-QSAR Studies, 1st International Workshop-cum-Training Course on Molecular Medicine and Drug Research held in Dr. Panjwani Center For Molecular Medicine & Drug Research, University Of Karachi, on January 16-30.
20) Afshan Naz, Naheed Akhter and Zaheer-ul-Haq, Comparative Molecular Docking Studies on CombretastatinsA-4 Analogues of Microtubule Inhibitors, 1st International Workshop-cum-Training Course on Molecular Medicine and Drug Research held in Dr. Panjwani Center For Molecular Medicine & Drug Research, University Of Karachi, on January 16 - 30.
19) Uzma Mahmood, Rabia Sattar and Zaheer-ul-Haq, 1st International Workshop-cum-Training Course on Molecular Medicine and Drug Research held in Dr. Panjwani Center For Molecular Medicine & Drug Research, University Of Karachi, on January 16 - 30.
2006
18) Zaheer-ul-Haq, M. Arif Lodhi and M. Iqbal Choudhary, Insights into the Metal Chelating Mechanism in Biscoumerine Interaction Using Molecular Docking Simulation and Comparative Field Analysis, “20th "Darmstadt" Molecular Modeling Workshop” Computer-Chemie-Centrum, Erlangen, Germany, May 23 – 24.
17) Zaheer-ul-Haq, and M. Iqbal Choudhary, The Role of Computational Chemistry in the Process of Drug Discovery, 6th International & 16th National Chemistry Conference, held in Bahauddin Zakariya University, Multan on April 6-8.
16) Sajjad Hussain, Nessar Ahmed, Zaheer-ul-Haq, M. Iqbal Choudhary and Mark Slevin, Identification and characterization of natural products as anti-angiogenic drug candidates. Manchester Metropolitan University, Research Institute for Health & Social Change (RIHSC) 2006 Annual Conference, July 3.
2005
15) Zaheer-ul-Haq, Asaad Khalid and M. Iqbal Choudhary, Comparative Molecular Field Analysis (CoMFA) of Natural Cholinesterase-Inhibiting Steroidal Alkaloids, 2nd International Conference of the Division of Pharmaceutical and Drug Industry” held in Cairo, Egypt on March 6-10.
2004
14) Zaheer-ul-Haq, Khalid, A., Choudhary, M. I. and Atta-ur-Rahman, The Importance of Computational Chemistry in Drug Design: A CoMFA Approach to Steroidal Alkaloids Cholinesterase Inhibitors, 4th International & 14th National Chemistry Conference, The Chemical Society of Pakistan, May 16-18.
13) Gilani, A. H., Ghayur, M. N., Zaheer-ul-Haq, Atta-ur-Rahman, Cardiovascular tone Modulartory Action of Sarcococca saligna, Spring 2004 Meeting, Hulme Hall, University of Manchester, British Society for Cardiovascular Research.
12) Zaheer-ul-Haq, Wellenzohn, B., Tonmunphean, S., Khalid, A., Choudhary, M. I. and Rode, B. M. 3D-QSAR Studies on Natural Acetyl-cholinesterase Inhibitors of Sarcococca saligna by Comparative Molecular Field Analysis (CoMFA). 9th International Symposium on Natural Product Chemistry, Karachi, Pakistan, Jan. 10-13.
11) Khalid, Zaheer-ul-Haq, M. N. Ghayur, Atta-ur-Rahman, A. H. Gilani and M. I. Choudhary, Structural Basis of Acetylcholinesterase Inhibition by Steroidal Alkaloids, 9th International Symposium on Natural Product Chemistry, Karachi, Pakistan, Jan. 10-13.
10) F. Feroz, Atta-ur-Rahman, M.I. Choudhary, Zaheer-ul-Haq, S. A. Nawaz and M R. Khan, Structure Activity Relationship of Steroidal Alkaloids from Sarcococca saligna Against Acetyl- and Butyryl-Cholinesterase Enzyme, 9th International Symposium on Natural Product Chemistry, Karachi, Pakistan, Jan. 10-13.
9) M. N. Ghayur, M. Zain-ul-Sajadeen, A. H. Gilani, Zaheer-ul-Haq. S. K. Kalauni, A. Khalid, M.I. Choudhary, Atta-ur-Rahman, Antidiarrhoeal and Antisecretory Constituents in Sarcococca saligna, 9th International Symposium on Natural Product Chemistry, Karachi, Pakistan, Jan. 10-13.
2002
8) Zaheer-ul-Haq, Atta-ur-Rahman, M.I. Choudhary, A. Khalid, S. Anjum and M.R. Khan, New Acetylcholinesterase Inhibitors from Sarcococca saligna, 7th Euroasia Conference on Chemical Sciences, Karachi, Pakistan, March 9-12. [First prize winning poster].
7) Khalid, M.I. Choudhary, M.K. Azim, S. Parveen, Zaheer-ul-Haq, Atta-ur-Rahman and S.A.M. Ayatollahi, Kinetic and Molecular Docking Studies on New Natural Cholinesterase Inhibitors, 2nd International & 12th National Chemistry Conference, Jamshoro, Pakistan, Feb. 4-6.
6) Atta-ur-Rahman, Zaheer-ul-Haq, A. Khalid, S. Anjum, M. R. Khan, and M. I. Choudhary, New Discoveries of Cholinesterase Inhibitors Studies from a Pakistani medicinal Plant, 2nd International and 12th National Chemistry Conference, University of Sindh, Jamshoro, Pakistan.
5) S. Anjum, Zaheer-ul-Haq, Atta-ur-Rahman, M. I. Choudhary and S. Aziz, Quantitative Estimation of Bilirubin by Hig Performance Liquid Chromatography (HPLC), HPLC2002, Montreal, Canada, June.
2001
4) F. Feroz, Zaheer-ul-Haq, S. Anjum, Atta-ur-Rahman, and M.I. Choudhary, Synthetic Studies Towards Quinoxaline Derivatives and Rearrangement of Benzisoxazole System, 1st International and 11th National Chemistry Conference, Department of Chemistry, Peshawar, April 10 – 14.
3) Zaheer-ul-Haq, Atta-ur-Rahman, M.I. Choudhary, S. Anjum, A. Khalid and M.R. Khan, Bioassay-Guided Isolation of New Class of Acetylcholinesterase Inhibitors from Sarcococca saligna, 1st International and 11th National Chemistry Conference, Department of Chemistry, Peshawar, April 10 – 14.
2000
2) Nuzhat Ahmed, Nazia Jalil, Zaheer-ul-Haq, Viqar-uddin Ahmad and Atta-ur-Rahman Commercially Important Products from Marine Bacteria: Marine Biotechnology, International Symposium on Marine Natural Products Chemistry, H.E.J. Research Institute of Chemistry University of Karachi.
1) Zaheer-ul-Haq, Atta-ur-Rahman, M.I. Choudhary, S. Anjum and A. Khalid, Discovery of New Acetylcholinesterase Inhibitors from Sarcococca saligna, 8th International Symposium on Natural Product Chemistry, Karachi, Pakistan, Jan. 18-22.