Publications

2025 Min, H.G., Wee, J., Kim, Y., Hyun, S., Sim, C., Kim, H.S., Cho, K. and Lee, Y.S., Forest soil properties regulate arsenic mobility and life stage-specific ecotoxicity in Collembola: Implications for early-stage contamination risk. Journal of Hazardous Materials, p.139737

2025 Wolkoff, M., Yoshida, M., Taylor, L., Sim, C., Meuti, M., The cycle gene is essential for both daily responses and seasonal reproduction in the Northern house mosquito, Culex pipiens. Sci Rep 15, 28279.

2025 Dhunganaa, P*., Wei, X*., Kang, D, Sim, C. A head-specific transcriptomic study reveals key regulatory pathways for winter diapause in the mosquito Culex pipiens. Archives of Insect Biochemistry and physiology, 118, e70032. 

2025 Martynova, T*., King, B*., Dhungana, P*., Wei, R*. and Sim, C. A shut-down in expression of a male-specific aminopeptidase impedes male reproductive success of the mosquito Culex pipiens. Physiological Entomology, 

2025 Wei, X., Dhungana, P., Callender, K., Zewde, B., Chen, F., Kim, S. and Sim, C. Suppression of the H3K27me3 demethylase disrupts diapause formation in mosquito Culex pipiens. Insect biochemistry and molecular biology, 176, p.104216.

2024 Dhungana, P*. and Sim, C. Genome-wide identification of PAR domain protein 1 (PDP1) targets through ChIP-seq reveals the regulation of diapause-specific characteristics in Culex pipiens. Insect Molecular Biology 33(6):777-791.

2024 Wei, R*. and Sim, C. Transcription profiling reveals tissue specific metabolic pathways in the fat body and ovary of the mosquito Culex pipiens. Comp Biochem Physiol Part D Genomics Proteomics 27:51:101260.

2024 Bianco, O., Abdi, A., Klein, M., Wei, X*., Sim, C., Meuti, M. Consuming royal jelly alters several phenotypes associated with overwintering dormancy in mosquitoes. Frontiers in Insect Science 4:189 (doi:10.3389/fphys.2013.00189), 10 pages

2023 Dhungana, P., Wei, X., Meuti, M. and Sim, C., Identification of CYCLE targets that contribute diverse features of circadian rhythms in the mosquito Culex pipiens. Comparative Biochemistry and physiology. Part D, Genomics & Proteomics, 48, pp.101140-101140.

2023 Wei, X., Dhungana, P. and Sim, C., The diapausing mosquito Culex pipiens exhibits reduced levels of H3K27me2 in the fat body. Insect molecular biology.

2023 Lee, Y.S*., Park, B.C., Lee, D.B., Min, H.G., Kim, M.S., Kim, S.C., Won, S.O., Wee, J., Chae, E., Sim, C. and Kim, Y., Crystallization-based upcycling of iron oxyhydroxide for efficient arsenic capture in contaminated soils. Environment International, p.107963.

2023 King, B., Larsen, M., Ikenga, A. and Sim, C., Suppression of the gene encoding PDZ domain-containing protein decreases cold tolerance and overwintering survival of the mosquito, Culex pipiens (Culicidae: Diptera). Journal of Medical Entomology.

2022 Arora, A.K., Sim, C., Severson, D.W., Kang, D.S. 2022. Random forest analysis of impact of abiotic factors on Culex pipiens and Culex quinquefasciatus occurrence. Frontiers in Ecology and Evolution. 9:773360. https://doi.org/10.3389/fevo.2021.773360.

2022    Martynova, T., Kamanda, P., & Sim, C. Transcriptome profiling reveals sex‐specific gene expressions in pupal and adult stages of the mosquito Culex pipiens. Insect Molecular Biology. 31 (1), 24-32

2021    King, B*., Ikenga, A*., Larsen, M*., Sim, C. Suppressed expression of oxidoreductin-like protein, Oxidor, increases follicle degeneration and decreases survival during the overwintering diapause of the mosquito Culex pipiens. Comparative Biochemistry and Physiology,  Comparative Biochemistry and physiology. Part A, Molecular & Integrative Physiology, 260, pp.111037-111037.

2021 Kang, D*., Kim, S*, Cotten, M*, Sim, C. Transcript assembly and quantification by RNA-Seq reveals significant differences in gene expression and genetic variants in mosquitoes of the Culex pipiens complex. Journal of Medical Entomology, 58(1):139-145.

2020 Olademehin, O., Liu, C., Rimal, B*., Adegboyega, N., Sim, C., Kim, S. J. Dsi-RNA injection targeting genes regulated by Foxo transcription factor reduce glycogen and lipid storage in diapause Culex pipiens. Scientific Reports, 10 (1):17201.

2019     King, B*., Shijia, L*., Liu, C., Kim, S., Sim, C. Suppression of glycogen synthase expression reduces glycogen and lipid storage during mosquito overwintering diapause. Journal of Insect Physiology, 120, 103971.         

2019 Kim, H., Ryu, S., Park, J., Yu, D., Chae, J., Choi, K., Sim, C., Park, B. Urogonimus turdi (Digenea: Leucochloridiidae) from the White's Thrush, Zoothera aurea, in the Republic of Korea. K. J. Parasitology 57, 461-467.

2018 Kim, S*., Lee, R*, Sim, C. New SNP markers to identify Culex complex species (Diptera: Culcidae) by high-resolution DNA melting analysis. Journal of Medical Entomology, 55(6), 1446-1452.

2018 Kim, S*., Trocke, S*., Sim, C. Comparative studies of stenogamy behavior in the mosquito Culex pipiens complex. Journal of Medical and Veterinary Entomology, 32(4), 427-435.

2018 Choi, T., Hong, E., Ryu, S., Sim, C., Chae, J., Kim, H., Park, J., Choi, K., Yu, D., Yoo, J., Park, B. Detection and Identification of Sarcocystis cruzi (Protozoa: Apicomplexa) by Molecular and Ultrastructural Studies in Naturally Infected Korean Cattle (Bos taurus coreanae) from Daejeon, Korea. K. J. Parasitology, 56(2), 121-127.

2017 Ha, N., Hong, E., Ryu, S., Sim, C., Chae, J., Kim, H., Park, J., Choi, K., You, D., Park, B. Morphological and molecular finding of Longicollum pagrosomi (Acanthocephala: Pomphorhynchidae) in cultured red sea bream from Korea. K. Journal of Veterinary Service, 40(3), 169-175.

2017 Kang, D. S*., Thomas, R., Sim, C. The Effects of Temperature and Precipitation on Culex quinquefasciatus (Diptera: Culicidae) Abundance: A Case Study in the Greater Waco City, Texas. Vector Biol J, 2:1, 1000116.

2016 Chang, J., Singh, J., Kim, S*., Hockaday, B., Sim, C., Kim, S. J. Solid-state NMR reveals differential carbohydrate utilization in diapausing Culex pipiens. Scientific Reports, 6, srep37350.

2016 Kang, D. S*., Cotten, M. A*., Denlinger, D. L., Sim, C. Comparative Transcriptomics reveals key gene expression differences between diapausing and non-diapausing adults of Culex pipiens. PloS one, 11(4), e0154892.

2016 Hong, E., Sim, C., Chae, J., Kim, H., Park, J., Choi, K., Yu, D., Park, C., Yoo, J., Park, B. Ultrastructural and molecular identification of Sarcocystis tenella (Protozoa, Apicomplexa) in naturally infected Korean native goats. Veterinarni Medicina, 61(7), 374–381.

2016 Lim, C.-W., Han, S., Kim, B., Alexander, U., Lee, Y.-R., Park, T.-G., Park, K. J., Kim, D.-N., Sim, C., Sohn, H., An, D.-H. Nasitrema attenuata (Digenia: Nasitrematidae) Infection of Longbeaked Common Dolphin (Delphius capensis) in the East Sea, Korea. Journal of veterinary clinics, 33(3), 151–154.

2016 Hong, E.-J., Sim, C., Chae, J.-S., Kim, H.-C., Park, J., Choi, K.-S., Yu, D.-H., Yoo, J.-G., Park, B.-K. A Horsehair Worm, Gordius sp. (Nematomorpha: Gordiida), Passed in a Canine Feces. K. Journal of parasitology, 53(6), 719-724.

2015 Sim, C., D. Kang*, S. Kim*, X. Bai and D.L. Denlinger. Identification of FOXO targets that generate the diverse features of the diapause phenotype in the mosquito Culex pipiens.  Proceedings of the National Academy of Sciences, USA 112: 3811-3816.

2015 Kang, D*., and C. Sim. Identification and assessment of single nucleotide polymorphisms (SNPs) between Culex complex mosquitoes. Molecular Ecology Resources. 15 (1); 228, 13 pages.

2015 Suh, E., C. Sim, J. Park and K. Cho. Inter-population variation for Wolbachia induced reproductive incompatibility in the haplodiploid mite Tetranychus urticae. Experimental and Applied Acarology. 65 (1); 55-71.

2015 Kim, H.C., Park J., Yu D.H., Chae J.S., Yoo J.G., Sim C., K.S. Choi, and B.K. Park. A Survey and Morphological Study of Plerocercoidal Nybelinia surmenicola (Cestoda: Tentaculariidae) in the Common Squid from the Korean Coastal Waters. Journal of Veterinary Clinic 32 (3): 239-242.

2014 Sim, C. is a co-author and a member of International Glossina Genome Initiative.  Genome sequencing of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis. Science 344:380-386.  Cover story and photo.

2014 Kang, D*., D.L. Denlinger and C. Sim. Suppression of allatotropin simulates reproductive diapause in the mosquito Culex pipiens. Journal of Insect Physiology. 64:48-53.

2013 Kang D*. and C. Sim. Identification of Culex complex species using SNP markers based on high resolution melting analysis. Molecular Ecology Resources, 13: 369-376.

2013 Sim, C. and D.L. Denlinger. Juvenile hormone III suppresses forkhead of transcription factor in the fat body and reduces fat accumulation in the diapausing mosquito Culex pipiens. Insect Molecular Biology 22:1-11.

2013 Sim, C. and D.L. Denlinger.  Insulin signaling and the regulation of insect diapause.  Frontiers in Physiology 4:189 (doi:10.3389/fphys.2013.00189), 10 pages

2013 Sim, C., H.C. Kim, H.Y. Son, J.Y. Jung, S.Y. Ryu, and B.K. Park. Description of peritoneal cavity dirofilariosis caused by Dirofilaria immitis (Filarioidea: Onchocercidae) in a dog: a case report. Veterinarni Medicina 58: 105-108.

2012 Harker, B.W., Y.S. Hong, C. Sim, A. Dana, R. Bruggner, N. Lobo, M.K. Kern, M. Sharakhova, and F.H. Collins. Transcription profiling associated with life cycle of the malaria mosquito Anopheles gambiae. Journal of Medical Entomology, 49(2): 316-325.

2012 Chae, J.S., K.P. Myeong, H.C. Kim, J.Y. Jung, H.Y. Son, S.Y. Ryu, H.J. Shin, C. Sim and B.K. Park. Infection status of metacercaria in adult dragonflies from Republic of Korea. International Journal of Veterinary Science, 1(2): 55-58.

2012 Chae, J.S., K.P. Myeong, H.C. Kim, J.Y. Jung, H.Y. Son, S.Y. Ryu, H.J. Shin, C. Sim and B.K. Park. Ultrastructural study of the three trematodes Plagiorchis muris, Pleurogenoides japonicus and Loxogenes liberum collected from dragonflies. International Journal of Veterinary Science, 1(2): 59-63.

2011 Sim, C. and D.L. Denlinger. Catalase and superoxide dismutase-2 enhance survival and protect ovaries during overwintering diapause in the mosquito Culex pipiens.  Journal of Insect Physiology 57:628-634.

2010 Kim, N.S., H.C. Kim, C. Sim, J.R. Ji, N.S. Kim and B.K. Park, Congenital infection with Setaria digitata and Setaria marshalli in the thoracic cavity of a Korean calf: a case report. Veterinarni Medicina 55, 275-280.

2010 Kim, M., C. Sim and D.L. Denlinger. RNA interference directed against ribosomal protein S3a suggests a link between this gene and arrested ovarian development during adult diapause in Culex pipiens. Insect Molecular Biology 19: 27-33.

2009    Sim, C. and D.L. Denlinger. A shut-down in expression of an insulin-like peptide, ILP-1, halts ovarian maturation during the overwintering diapause of the mosquito Culex pipiens.  Insect Molecular Biology 18:325-332.

2009    Sim, C. and D.L. Denlinger. Transcription profiling and regulation of fat metabolism genes in diapausing adults of the mosquito Culex pipiens.  Physiological Genomics 39:202-209. 

2008    Sim, C. and D.L. Denlinger. Insulin signaling and FOXO regulate the overwintering diapause of the mosquito Culex pipiens.  Proceedings of the National Academy of Sciences, USA 105:6777-6781.

2008 Kang, S., C. Sim, B. Byrd, F.H. Collins and Y.S. Hong. Ex vivo promoter analysis of antiviral heat shock cognate 70B gene in Anopheles gambiae. Virology Journal, 5:136, 1-9. 

2007 Sim, C., Y.S. Hong, K.A. Tsetsarkin, D.L. Vanlandingham, S. Higgs, F.H. Collins. Anopheles gambiae heat shock protein cognate 70B impedes o'nyong-nyong virus replication. BMC Genomics, 8:231,1-12.

2006 Kim, M., C. Sim, D. Shin, E. Suh and K. Cho. Residual and sublethal effects of fenpyroximate and pyridaben on the instantaneous rate of increase of Tetranychus urticae. Crop Protection 25: 542–548.

2005 Sim, C., Y.S. Hong, D.L. Vanlandingham, B.W. Harker, G.K. Christophides, F.C. Kafatos, S. Higgs and F.H. Collins. Modulation of Anopheles gambiae gene expression in response to o'nyong nyong virus infection. Insect Molecular Biology, 14: 475-481.

2003 Sarkar, A., C. Sim, Y.S. Hong, J.R. Hogan, M.J. Fraser, H.M. Robertson and F.H. Collins. Molecular evolutionary analysis of the widespread piggyBac transposon family and related "domesticated" sequences. Molecular Genetics Genomics, 270: 173-180. 

2003 Hong, Y.S., J.R. Hogan, X. Wang, A. Sarkar, C. Sim, B.J. Loftus, C. Ren, E.R. Huff, J.L. Carlile, K. Black, H.B. Zhang, M.J. Gardner, and F.H. Collins. Construction of a BAC library and generation of BAC end sequence-tagged connectors for genome sequencing of the African malaria mosquito Anopheles gambiae. Molecular Genetics Genomics, 268: 720-728.

2003 Sim, C., E. Seo, and K. Cho. Life table and sensitivity analysis as fitness evaluation method of fenpyroximate and pyridaben resistant twospotted spider mite (Tetranychus urticae Koch). Journal of Asian-Pacific Entomology. 6: 193-199.

2002 Thomasova, D., L.Q. Ton, R.R. Copley, E.M. Zdobnov, X. Wang, Y.S. Hong, C. Sim, P. Bork, F.C. Kafatos, and F.H. Collins. Comparative genomic analysis in the region of a major Plasmodium-refractoriness locus of Anopheles gambiae. Proceedings of the National Academy of Sciences, USA 99: 8179-8184.