We invite you to participate in the 24th Transporter- and Barrier – Days taking place in Bad Herrenalb/Black Forest close to Karlsruhe, Germany, from May 26st to May 28th, 2025. 


Subjects of this conference are membrane transport proteins in barrier organs, drug transport and drug delivery across biological membranes, screening models such as MCDK, Caco-2 cells, blood brain barrier cells, skin cells, hepatocytes and others as well as phospholipids in drug delivery. Please forward this message also to colleagues in your department. This conference might also be of special interest for PhD students to get in contact with participating colleagues from the pharma industry.  


Please register and submit an abstract for poster or oral presentation until Monday, May 15th 2025.  Registration fee is 350,- € covering 2 nights with complete room and board (breakfast, lunch, dinner). In case of questions please call +49-6221-548336 or send an email to transportertage@googlemail.com


Herrenalber Transportertage 



We thank our sponsors : 

Preliminary Program

 




to be continued   


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Previous Topics of this Conference

      Dual targeting immunoliposomes for drug delivery to the brain

      Ox26-immunoliposomes to target the blood-brain-barrier 

      Altered protein expression of ABC and SLC transporters in brain microvessels and cortex of familial Alzheimer´s disease models

      Impact of sodium arsenite on ABC transport proteins 

      Establishment of a fast and efficient extraction method for lysophosphatidylcholine by dual centrifugation

      Targeted Lipid Nanoparticles for delivery of mRNA into Central Nervous System

      TNFα modulation of secretion and Ca2+ signaling in small intestinal murine organoids

      Slc23a3: the long sought ascorbate release carrier!

      Translational aspects of oxycodone brain delivery via the proton-coupled organic cation (H+/OC) antiporter in rats and pigs

      Comparative analysis of clinically used paclitaxel formulations with a focus on the extent of paclitaxel transport across the CNS and PNS barriers

      The possible role of sodium/proton exchangers in exocrine fluid secretion

      Rational Selection and Design of Combinational Liposomes Using Phytochemicals

      Stabilization of LysoPC-levels in Patients with Cancer

      SLC Transporter: The metabolic gate of Immune cells

      Striatal blood-brain barrier permeability fluctuates perinatally

      Manipulating the microbiota with vancomycin and high-fibre diet affects SCFA/FFA receptor signalling in rat caecum 

      A novel fluorescent substrate for P-Glycoprotein-mediated vesicular and cellular transport assays

      Computational Biopharmaceutics: Biopredicitve technologies in the nanomedicine design space

      MemCross: Molecular dynamics simulations of passive permeation and co-permeation"

      Expression of transporters in Alzheimer's disease: does sex matter?".

      Nanoparticles targeting solute carriers to cross the blood-brain barrier

      Targeting of hepatocytes using a virus-mimetic nanocarrier

      Brain regional drug distribution: relevance to Alzheimer’s disease treatment"

      New Concepts of Pathogenesis and Therapy of Colitis Ulcerosa

      OCTN1 and COPD - Is there a role for drug transporters in pulmonary disease

      Recent attempts to surpass the BBB to treat brain disorders

      Nanoparticle-bound doxorubicin for chemo-therapy of glioblastoma: Update on clinical trials

      Anti-HIV and anti-HCV drugs inhibit p-glycoprotein efflux activity in Caco-2 cells and precision-cut rat and human intestinal slices

      Are PLGA-based glutathione-modified nanoparticles sufficient to cross the blood-brain barrier?

      Assessing the interaction of micro-tumors with cellular barriers in a scalable microfluidic in vitro model

      Availability, Affinity and Avidity: Optimising Transcytosis Properties of Central Nervous System Delivery Systems using Computational Approaches

      Bacteria-derived vesicles show low cytotoxicity but inherent antimicrobial activity against model pathogens

      Cell Specific Effects and Mechanisms Mediated by 1, 25-dihydroxyvitamine D3 in the Protection of Alveolar-capillary Barrier

      Cell-free transport protein expression

      Changes of tricellular tight junction proteins in Crohn’s disease

      Coating of PLA-nanoparticles with cyclic, arginine-rich cell penetrating peptides enables oral delivery of liraglutide

      Combinational Nano-formulation for Increasing Therapeutic Efficacy by Targeting ABC Transporters in Cell-based Models

      Development and testing of a CNS-penetrating translationally relevant TRAIl-variant

      Efficiently targeting drug efflux through modulation of p-glycoprotein activity by small molecules: Design, Synthesis biological and computational study.

      Elucidation of possible distinct digoxin-binding sites within the substrate-binding pocket of P-glycoprotein

      Engineered Protein Capsules as drug delivery platform for treatment of CNS diseases

      Establishment and validation of a viable in vitro skin model from different species for the evaluation of cutaneous diseases

      Exploring the role of the constrictions and the central histidine in Formate-nitrate-transporters

      From human induced pluripotent stem cell to barrier-building endothelial cells - Using a realistic model of the blood-brain barrier for the identification of essential nanoparticle  characteristics as drug delivery systems

      Functional characterization of human intestinal ABC and SLC transport proteins in overexpression models and ex vivo intestinal tissue segments

      Hypergravity on Brain Blood Barrier opening : benefit or alteration ?

      Imitating Lipoproteins as Drug Delivery System - Apolipoprotein E-modified Lipid Nanoparticles

      Impact of intestinal and renal membrane transporter ABCB1 gene polymorphisms on the pharmacokinetics of digoxin in healthy Caucasian subjects

      In vitro tools to investigate creatine transport inhibition

      Investigation of apical drug transporter activity using ex vivo porcine intestine to facilitate identification of potential drug-drug-interactions at an early state of drug development

      L-type amino acid transporter 1 utilizing prodrugs: promising approach to targeted brain delivery of CNS drugs

      Measurement of intracellular unbound drug concentrations

      Monitoring Penetration of Target Specific Active Ingredients by Using a Depth Profiling Approach

      Monocarboxylate Transporter 8 Expression Profile: Constant Protein Abundance in Barriers of the CNS versus Developmental Decline of Neuronal Expression

      Multidrug resistance protein 4 (MRP4) excretes paracetamol glutathione and cysteine conjugates from liver and kidney

      Novel Developments and Challenges of Blood-Brain Barrier in vitro Models

      Organ-on-a-Chip technology: 3D human blood-brain-barrier, kidney, and gut models for high-throughput barrier and transport measurements

      Peptide conjugation of glycopeptide antibiotics leads to conjugates that overcome all types of resistance P-gp inhibition in human stem-cell derived brain endothelial cells by Group B Streptococcus

      PLGA nanoparticles for oral drug delivery: Influence of polymer end groups and particle size on permeability in the Caco-2 model

      Self-assembled α-tocopherol transfer protein nanoparticles promote vitamin E delivery across an endothelial barrier

      SLC26A9 as an alternative epithelial Cl- channel in muco-obstructive lung diseases

      Species differences of hNTCP and mNtcp in transport characteristics and the inhibitory potential of selected drugs and pesticides

      Suggestions for improved experimental design of small molecule transfer and transport studies with two compartment cell culture models

      The Aη peptide Impairs LRP-1 dependent clearance of Amyloid β at the BBB

      The blood-brain barrier in obesity – tracing leptin through the endothelial cell

      The blood-saliva barrier: Establishment of in vitro models of the human salivary gland and further characterization of isolated colonies.

      The in vitro evaluation of inhibitory potency of anti-HIV and anti-HCV drugs on P-glycoprotein; impact on digoxin intestinal absorption

      The role of LRP1 in stroke therapy with Actilyse

      Transport of glucose-derived ß-carboline alkaloids across the Caco-2 cell monolayer

      Transport of nucleoside-derived antivirals across the rat and human placental barrier: roles of nucleoside and ATP-binding cassette drug efflux transporters