Research

Research interest

Research Interest:

Work Area:

ü  Properties and characterization of biopolymer (Carrageenan, agar, gelatin, chitosan, poly(vinyl alcohol), carboxymethyl cellulose, cellulose nanofiber, etc.) and bioplastic (poly(lactic acid), poly(butylene adipate-co-terephthalate), etc.) nanocomposite films for active packaging application.

ü  Preparation of intelligent pH sensor film for monitoring freshness of food using natural colorant (anthocyanin, shikonin, curcumin, alizarin, etc.) and various biopolymers-based matrices.

ü  Preparation and characterization of bio-based sustainable edible cutlery using a combination of various flours and bioactive functional compounds.

ü  Preparation and characterization of nanocellulose fiber from wood pulp (hard and soft type) using TEMPO oxidation and aqueous counter collision (ACC) technique.

ü  Fabrication of polysaccharides-polysaccharides and polysaccharides-protein-based binary functional composite film.

ü  Surface modification of halloysite nanotube and its use in fabrication of active packaging film.

ü  Biosynthesis of metallic nanoparticles (Ag, CuO, ZnO, CuS, ZnS, Au, CdS) and their characterization using different biophysical and biochemical techniques.

ü  Effect of metal and metal oxide, sulfide nanoparticles (Ag, CuO, ZnO, ZnS, CuS) on the physical, mechanical, and antimicrobial properties of biopolymer film.

ü  Effect of natural bioactive functional materials (melanin, curcumin, grape seed extract, etc.) on the physical, UV-barrier, mechanical, antioxidant, and antimicrobial properties of biopolymer and bioplastic film.

ü  The study on the effect of biosynthesized metallic nanoparticles on fungi, bacterial cells, and human cell lines.

ü  Investigation of interaction between metallic nanoparticles and biomolecules (Protein, DNA) using spectroscopic techniques.

ü  Investigation of interaction between organic synthetic compounds and biomolecules (Protein, DNA) by different spectroscopic techniques and docking methods.

ü  Synthesis of conducting polypyrrole-metal oxide (V2O5, TiO2, Fe3O4, ZnO) nanocomposite: a study of structural, optical, and electrical properties.

 

Summary of doctoral research work:

The primary focus of my work was microbial biosynthesis of metallic nanoparticles. I had worked on the biosynthesis of silver, gold, and cadmium sulfide nanoparticle using a fungal strain Aspergillus foetidus. I have also studied the antimicrobial (antifungal and antibacterial) activity of the prepared nanoparticles against several Aspergillus Sp. and E. coli and S. Aureus. Furthermore, I worked on the effect of silver nanoparticles (AgNP) and gold nanoparticles (GNP) on human cell line and cytotoxicity, cell viability study conducted. In addition, I worked on the effect of biosynthesized AgNP on the growth and some biochemical parameters of A. foetidus. Additionally, I had studied the interaction between biosynthesized metallic nanoparticles (silver, gold) and biomolecules (Protein, DNA, Amino acids) using the multi-spectroscopic approach. What is more, I had also studied the interaction of different biologically active organic synthetic compounds (Phosphorous heterocycles, spiro-pyrimidines, etc.) and biomolecule (Bovine serum albumin and calf thymus DNA) using different spectroscopic (Fluorescence, Circular dichroism, UV-vis, etc.) and docking method.


Summary of 1st postdoctoral research work:

The main aim of the work was the preparation and characterization of inorganic-organic hybrid conducting polymer composite materials. I had worked on synthesis and characterization of conducting polymer and metal oxide nanocomposite using a simple chemical synthesis route and its application. I had prepared conducting polypyrrole-metal oxide (ZnO, V2O5, TiO2, etc.) nanocomposite using a simple fabrication process and studied the structural, optical, and electrical properties. Electrical conductance and dielectric behavior of the electrical phenomena of the sample have also been investigated. In addition, I have worked on the synthesis and characterization of silicon nanowire using metal-induced etching. Furthermore, I had also studied the investigation on the interaction of nanoparticles/organic compounds with protein (BSA, Lysozyme), and DNA (calf thymus DNA) using a multi-spectroscopic and docking approach.


Summary of 2nd postdoctoral research work:

The primary goal of the work was the preparation of biopolymer-based composite film with improved physical and functional properties. Various biopolymer (Carrageenan, agar, gelatin, chitosan, CMC, polyvinyl alcohol, alginate, etc.) and bioplastic (PLA, PBAT) have been used to prepare the biopolymer-based composite film, and the physical and functional properties have been studied by the reinforcement of various materials such as metal nanoparticles (Ag), metal oxide nanoparticles (ZnO, CuO), metal sulfide (CuS), organic nanoparticles (Melanin) and natural product (Curcumin, Grapefruit seed extract). Different nanoparticles used for the preparation of nanocomposite film have also been synthesized using the simple and eco-friendly method. All the prepared environmentally friendly, biodegradable, and biocompatible bio-nano composite film with enhanced physical and functional properties are expected to be well suited for active food packaging as well as biomedical applications.


Summary of 3rd postdoctoral research work:

I worked on the preparation of cellulose nanofiber (CNF) based functional composite film. The CNF was extracted from hardwood pulp using a combination of chemical (TEMPO) and physical methods (Aqueous counter collision technique). The melanin nanoparticles (MNP) and synthetic melanin-like nanoparticle (MLNP) was synthesized and used to fabricate biopolymers-based (CNF, chitosan) nanocomposite film. Fabrication CNF-based active packaging film integrated with ZnO nanorod and grapefruit seed extract.  Development of functional bio-nanocomposite film using chitosan and TiO2 nanoparticles. Additionally, I have also worked on the synthesis of lignin-derived epoxy resin and preparation of film specimen and its reinforcement in CNF filament to make a future composite of long filament fiber. 


Summary of 4th postdoctoral research work:

I worked on the preparation of smart pH sensitive and functional biopolymer-based composite film with improved physical and functional properties. Various biopolymer and bioplastic have been used to prepare the biopolymer-based composite film, and the physical and functional properties have been studied by the reinforcement of various materials such as (ZnS, CuS, CNC, Melanin, nano clay etc.) and natural product (Curcumin, grapefruit seed extract, limonene, quercetin, rutin, propolis extract, essential oils, etc.). Pickering essential oil (cove, tea tree oil etc.) emulsion was prepared using nanocellulose fiber as solid matrix and utilized for making active packaging film. In addition, as color indicators, shikonin, anthocyanin, and alizarin have been used. The nanoparticles used (CNC, ZnS, CuS, Melanin, Nanoclay) for the preparation of biopolymer-based nanocomposite film have also been synthesized using the simple and ecofriendly method. All the prepared environmentally friendly, biodegradable, and biocompatible bio-nano-composite film with enhanced physical and functional properties are expected to be well suited for active food packaging as well as biomedical applications. The smart color indicator film could be utilized for detecting the freshness indicator of the food products.