Industry Experience

Roche Sequencing Solutions, Santa Clara CA

Director, Sub-Chapter Lead, Reagent Bioinformatics (04/2022 - Present)

• Lead the Reagent Bioinformatics team based in the US, Canada, and South Africa to build reagent kits for different platforms and translational applications. We provide analysis tools and data insights to advance technical improvements in novel library prep, target enrichment, automation systems, sequencing technologies, and enzyme/protein engineering.

Director, Global Medical Affairs, Pharma Services (05/2021 - 04/2022)

Senior Manager, Medical & Scientific Affairs, Oncology (11/2019 - 04/2021)

• Provided medical and scientific leadership to support commercialization of oncology CLIA services for biopharma partners

• Developed global medical strategy for NGS based testing and informatics solutions

• Provided medical input to commercial plans and run advisory boards to gather insights

• Generated and communicated scientific evidence on medical value of sequencing products (e.g., NAVIFY Mutation Profiler, AVENIO ctDNA and Tissue Analysis Kits)

• Served as scientific liaison with key customers and affiliates in various regions and countries

• Created training materials and delivered educational sessions internally and externally

• From 2017 to 2022, co-authored 13 journal publications (in Cancers, JMD, CCR, JCO PO, JTO) and 35 scientific meeting poster presentations (at ASCO, ESMO, ESHG, WCLC, AMP, ASH)

Manager, Bioinformatics (05/2019 - 10/2019)

Principal Scientist II, Bioinformatics (09/2017 - 05/2019)

Principal Scientist I, Bioinformatics (06/2015 - 08/2017)

• Led 9 direct reports across 3 sites in US and Germany to support multiple efforts, including:

  • Collaborate with experimentalists and algorithm developers to build analysis methods for innovative NGS-based end-to-end RUO and IVD products

  • Support on-market AVENIO ctDNA and Tissue Analysis Kits, and expand oncology pharma services in the Ariosa CLIA lab

  • Conduct analyses with clinical samples to showcase medical value and deliver real-world feedback

• Achievements:

  • Filed multiple invention disclosures on biomarkers and methods predicting response to therapy

  • Worked with key stakeholders to establish processes for clinical sample and data governance

  • Created several web-based tools to enable automated analyses for experimentalists

  • Supported product launch of three AVENIO ctDNA Analysis Kits and Oncology Analysis Software

  • Represented bioinformatics in global client-facing activities (early evaluation program) for AVENIO ctDNA, including site interview, selection, support, and performance evaluation

• Awards:

  • 2019 Roche Medical Value Summit Best Poster Award in "Digital Initiatives for Value Creation"

  • 2018 Roche Sequencing Solutions Team Award Runner Up for Scientific Innovation

  • 2017 Roche Sequencing Solutions Team Award Winner for Scientific Innovation

  • 2017 Roche Sequencing Solutions Team Award Runner Up for Process Innovation

  • 2016 Roche Sequencing Solutions Team Award Runner Up for Operational Innovation

Quantamerix, Cambridge MA

Co-founder (12/2011 - 05/2015)

• Co-invented a diagnostic technology for quantitating analytes with a paper-based test

• Raised $30,000 to fund R&D in a "garage lab" by winning awards in competitions, such as the MIT $100K Business Plan Competition, Harvard Innovation Lab President’s Challenge, InnoCentive Challenges sponsored by the National PKU Alliance, and grants from the MIT Legatum Center for Development and Entrepreneurship and MIT Public Service Center

• Press coverage in Boston Herald, BostInno, and Harvard Gazette

Genentech, South San Francisco CA

Intern, Late Stage Pharmaceutical & Processing Development (06/2010 - 08/2010)

• Probed biophysical properties of protein-ion binding using isothermal titration calorimetry

• Detected ion-specific binding interaction that could affect therapeutics in final formulations

Merck & Co., Inc., Rahway NJ

Intern, Analytical Development & Commercialization (06/2009 - 08/2009)

Received internship opportunity via 2009-2010 Merck Engineering & Technology Fellowship (awarded to 2 students at MIT)

• Built MATLAB scripts for real-time monitoring of spectroscopy and chemometrics of crystallization across production scales

• Received individual "Award of Excellence for a universal calibration model to support Merck’s strategy"

• Co-authored paper in the ACS journal Organic Process Research & Development

Roche Pharmaceuticals, Palo Alto CA

Intern, Non-Clinical Safety and Investigative Toxicology (06/2008 - 03/2009)

• Profiled 100 marketed and developmental drugs using 25 cell-based assays of cardiomyocyte function to evaluate safety

• Used cluster analysis to link kinase inhibition, mitochondrial function, and cardiotoxicity to build predictive models of toxicity

• Co-authored poster at the 2009 Society of Toxicology annual meeting

InVivo Therapeutics, Cambridge, MA

MIT VentureShip Program Participant and Intern (09/2006 - 05/2008)

• Assisted CEO in business strategy to address global acute spinal cord injury market

• Explored application for stem cell-polymer technology in $100M spinal cord tumor market

Agilent Technologies, Santa Clara CA

Intern, Diagnostics R&D and Marketing (05/2007 - 08/2007)

Intern, Molecular Diagnostics (06/2006 - 08/2006)

Received internship opportunity via award (to 20 students internationally) at 2006 Intel International Science & Engineering Fair

• Engineered automation workflow of diagnostic chip assay that reduced hands-on operator time by 60%

• Spearheaded new collaboration while conducting phone survey of top 100 US lab directors

• Created database of 300 genetic disorders to identify target markets for product development