anthi.katsiarimpa@ijm.fr

Background: After my studies as a Biochemist and Biotechnologist at the University of Thessaly in Greece I started in 2008 my PhD at the Department of Systemsbiology of Plants at the Technical University of Munich (TUM) in Germany. My doctoral thesis focused on the molecular characterization of two homologous deubiquitinating enzymes, called AMSH, in Arabidopsis thaliana and their impact in intracellular protein trafficking pathways, specifically in endocytosis and autophagy

My current work: I joined the Lab of Lionel Pintard as a Postdoctoral fellow in September of 2014. My current project is adressing the role of the ubiquitin system in controlling cell cycle progression in C. elegans by developing tools to identify ubiquitin modified proteins in early embryos.

Publications:

6-RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans.

Ossareh-Nazari B, Katsiarimpa A, Merlet J, Pintard L.

G3 (Bethesda). 2016 Aug 19. pii: g3.116.033043. doi: 10.1534/g3.116.033043. [Epub ahead of print].

5-The ESCRT-III-interacting deubiquitinating enzyme AMSH3 is essential for degradation of ubiquitinated membrane proteins in Arabidopsis thaliana.

Katsiarimpa A, Muñoz A, Kalinowska K, Uemura T, Rojo E, Isono E.

Plant Cell Physiol. 2014 Apr;55(4):727-36.

4-The deubiquitinating enzyme AMSH1 and the ESCRT-III subunit VPS2.1 are required for autophagic degradation in Arabidopsis.

Katsiarimpa A, Kalinowska K, Anzenberger F, Weis C, Ostertag M, Tsutsumi C, Schwechheimer C, Brunner F, Hückelhoven R, Isono E.

Plant Cell. 2013 Jun;25(6):2236-52.

3-The Arabidopsis deubiquitinating enzyme AMSH3 interacts with ESCRT-III subunits and regulates their localization.

Katsiarimpa A, Anzenberger F, Schlager N, Neubert S, Hauser MT, Schwechheimer C, Isono E.

Plant Cell. 2011 Aug;23(8):3026-40.

2-MLN4924 is an efficient inhibitor of NEDD8 conjugation in plants.

Hakenjos JP, Richter R, Dohmann EM, Katsiarimpa A, Isono E, Schwechheimer C.

Plant Physiol. 2011 Jun;156(2):527-36.

1-The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.

Isono E, Katsiarimpa A, Müller IK, Anzenberger F, Stierhof YD, Geldner N, Chory J, Schwechheimer C.

Plant Cell. 2010 Jun;22(6):1826-37.