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EDUCATION
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PhD in Computational Systems Biology, Norwegian University of Science and Technology, 2009-2012.(Defended in April 2013). [ Thesis title: Integrative systems approaches to study plant stress responses. ] Click here to access the PhD thesis electronically
M.Sc. in Bioinformatics, University of Madras, India. 2004-2006, First Class.
B.Sc. (Hons.), B. Barooah College, Gauhati University, India 2000-2003, First class with University Rank, Distinction.
Higher Secondary (Science), North Lakhimpur College, Assam, India 1998-2000, First division.
HSLC, Borbali Higher Secondary School, Assam, India 1998, First division, with star marks.
Core professional competency :
Computational Biology/ Bioinformatics
Mathematical modelling (stochastic and deterministic modelling of gene circuits, metabolic pathways, flux based modelling)
Molecular Biology, High throughput biology (OMICs)
Data analysis and integration
Computational Systems Biology
Network Biology
Protein structures
Multi Omics data integration (Genomics, Transcriptomics, Metabolomics, Proteomics, Next Gen Sequencing)
Gene-Ontology
Climate adaptation
Systems Medicine
Computational and bioinformatics skills:
Environment: Windows, UNIX / LINUX, IRIX, MAC.
Programming : PERL, MySQL, and HTML, CGI
Statistical Packages: MATLAB and R
Other Bioinformatics Tools and Packages: R-Bioconductor,Genome Analysis Toolkit (GATK), Burrows-Wheeler Aligner (BWA), Picard tools, ENCODE data portal, Ensembl, WGCNA, FASTX-Toolkit, cBioPortal for Cancer Genomics, RSAT -- Regulatory Sequence Analysis Tools, Pymol, SwissPDBV, Exome, Gromacs, VMD, AutoDock, Geno-Cluster, AMBER, PHYLIP, MEGA, GCG, Pajek, Cytoscape, Copasi, CellDesigner etc.
Working experience with Silicon Graphics Altix machine, Cluster and parallel computing.
Specialized Wet-lab Trainings:
Microarray - Hands on training on sample preparation, labeling, hybridization, scanning and data analysis using Affymetrix Gene Chip, Illumina Bead arrays, Agilent, Nimblegen.
High through put next generation sequencing : Whole Genome, Exome, Methylome ans Chip-seq
NMR and Mass Spectrometry for metabolite profiling: Hands on training on LC-MS, GC-MS, HPLC, MALDI-TOF, 2D NMR, In-vivo NMR with animal models.
Yeast two hybrid experiment and RNAi in C.elegans
Synthetic biology: Golden Gate cloning, CRISPR Cas9 Genome Editing, Gibson Assembly.
X-ray crystallography (demo)
Journey from a small village in Assam to the exciting world of science!
I was born in a small and remote village named Borbali [GPS Coordinates:27°02'44.0"N 93°51'30.7"E] in Assam, situated in the beautiful north-eastern part of India on the foothills of the Himalayas. Since my childhood, I have always been inclined towards the beauty and organisational complexity of the nature. I often used to go out to the wild for taking pictures, joining senior researchers in their field trips, writing popular science articles in local newspapers and magazines, visiting schools and villages to organise awareness camps for conservation of nature etc. Owing to my tremendous curiosity for nature, I have chosen biology as my field of studies.
I started my early education as a classical biologist with core training in Zoology, Botany and Chemistry. During my bachelor’s education, I was thrilled to read about the advancement in the genome technologies. I developed an interest to explore the world of modern genome technology. I shifted my discipline to bioinformatics and biotechnology. During my masters (University of Madras), I received interdisciplinary training in both molecular biology and computational biology. I did my masters project in two world class institutes in India (National Centre for Biological Sciences and Indian Institute of Sciences in Bangalore). It was an excellent opportunity for me to get exposure to the cutting edge research areas in the field of modern biology. During my masters internship, I worked on protein sequence, structure, function and evolution in highly divergent protein families. That was the turning point in my scientific career.
After completing my masters, I worked in a software company and in two national research laboratories in India for three years. Initially I worked as a Junior Research Fellow (JRF) at the Bioinformatics Centre, University of Pune for a year with a fellowship granted by the Department Biotechnology, Govt. of India.
Later, I moved to the Mathematical Modelling and Computational Biology Group at the Center for cellular and Molecular Biology, Hyderabad. I was successful in receiving a Senior Research Fellowship (SRF) in trans-disciplinary areas from the Council of Scientific and Industrial Research, Government of India.
The field of systems biology was evolving very fast. I received an offer from Norwegian Universityof Science & Technology to join as a PhD fellow in an exciting systems biology project (ERA-NET MultiStress) being a part of several universities in Europe. I worked closely with experimental biologist in a mega scale project. I received training in modern omics technologies, as well as computational modelling tools during this period. I have visited reputed labs, universities, institutes in more than 15 countries in Europe and USA interacting with researchers from diverse backgrounds.
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