Relevant laboratory research focuses on the construction of specific internal similarity in vitro cell / tissue culture models. One of the starting points is that drug development has gradually encountered bottlenecks in the past decade. The reason may be that the screening platform used can not effectively simulate the disease state in the human body. Moreover, animal experiments are quite different from humans, which leads to a waste of huge resources. Through our research, if we can successfully construct in vitro models similar to human systems, and can be more similar to the conditions of animal experiments, it can help scientist to understand the generation of diseases, assist doctors in drug treatment reference in disease treatment, and provide pharmaceutical companies as the basis for drug screening in the future.

Research topics include:

• Development of 3D in vitro tumor model 

• Development of 3D co-culture microfluidic system for drug discovery

• Characteristics of 3D tumor mechanics and migration in hydrogel

實驗室相關研究著重於建構具體內相似性的體外細胞/組織培養模型，此出發點其一是藥物開發近十幾年來逐漸遭遇瓶頸，原因或許是沿用之篩檢平台並無法有效模擬人體體內疾病狀態，且動物實驗亦與人體有相當程度的差異，進一步導致龐大資源的浪費，透過我們的研究，若能順利建構類似人體系統之體外模型，且能比動物實驗之條件更具相似性，未來將可幫助科研人員了解疾病的生成、協助醫生在疾病治療時的用藥參考、提供藥廠作爲藥物篩檢之依據。

相關的研究領域包含:

• 三維體外腫瘤模型建構 (Development of 3D in vitro tumor model) 

• 共培養微流體藥物篩檢平台開發（Development of 3D co-culture microfluidic system for drug discovery)

• 三維腫瘤在水凝膠的機械力學與爬行特性研究 （Characteristics of 3D tumor mechanics and migration in hydrogel)