Infant brain MRI

To understand how premature birth affects longterm brain development we need to be able to measure growth and volumes of different brain structures at different time-points, specificaly at birth, 1 year, 2 years and 6 years. The volume measurements of different populations of children will enable clinicians to answer questions, such as: Does the abnormal white matter and basal ganglia in neonates result in abnormal growth later on? Does the proportion of cortex to white matter follow the rules it should? During my PhD at Imperial College London I concentrated on accurate segmentation of brain structures in MRI at 1 and 2 years of age.

Relevant publications:

Segmentation of Brain MRI in Young Children. M Murgasova, L Dyet, AD Edwards, MA Rutherford, JV Hajnal, D Rueckert, Academic Radiology, 14(11), 2007.[pdf]

Robust segmentation of brain structures in MRI. M Murgasova, J Hajnal, AD Edwards, D Rueckert, ISBI 2009

Template-based bias correction: Application to paediatric brain MRI. M Murgasova, J Hajnal, S Counsell, AD Edwards, D Rueckert. ISMRM 2009, 4672.

PhD thesis:

Segmentation of brain MRI during early childhood. M Murgasova. Imperial College London, 2009.