The focus of our research lies at the interface between chemistry and biology, and is mainly oriented towards the design and synthesis of novel drug candidates for chronic and infectious diseases, trying to better understand and modulate different physiopathological processes. 

By applying modern green techniques (e.g., microwave synthesis, electrochemistry, click-chemistry, MCR etc), we explore the chemical diversity around biologically active chemical probes thus accelerating the drug-discovery process.

The synergistic collaboration with pharmacologists, biologists and clinicians all around the world has allowed us to discover new potential antiviral and anticancer drug candidates, which are the object of 5 patent applications and of several publications in high impact factor journals . 

Our ongoing research activities are focused at the integration of sustainable chemistry & in silico techniques to develop novel drug candidates for different Chronic Diseases (Cystic Fibrosis, IBDs, Hypercholesterolemia, Parkinson, Cancer) and Infective Diseases (SARS-CoV-2, Enterovirus, Flavivirus, Monkeypox, HIV).