Nature of science:
Serendipity and scientific discoveries—the discovery of cyclins was accidental. (1.4)
Understandings:
Mitosis is division of the nucleus into two genetically identical daughter nuclei.
Chromosomes condense by supercoiling during mitosis.
Cytokinesis occurs after mitosis and is different in plant and animal cells.
Interphase is a very active phase of the cell cycle with many processes occurring in the nucleus and cytoplasm.
Cyclins are involved in the control of the cell cycle.
Mutagens, oncogenes and metastasis are involved in the development of primary and secondary tumours.
Applications and skills:
Application: The correlation between smoking and incidence of cancers.
Skill: Identification of phases of mitosis in cells viewed with a microscope or in a micrograph.
Skill: Determination of a mitotic index from a micrograph.
Virtual Lab: Cell cycle and Cancer
Mitosis Animation: http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter2/animation__mitosis_and_cytokinesis.html
Mitosis Onion Root lab http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/cell_cycle.html
Animation on Cell cycle: http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter2/animation__how_the_cell_cycle_works.html
Interactive simulation on the cell cycle and cancer: http://mhhe.com/biosci/genbio/virtual_labs_2K8/labs/BL_03/index.html