Kirjallisuutta

Kryoniikkaa käsittelevää kirjallisuutta englanniksi. Sähköiset versiot saatavilla.

Engines of Creation by K. Eric Drexler. The book that introduced the word “nanotechnology” to the world. As riveting today as when it was published in 1986. Contains a chapter on cryonics. Highly recommended. A second edition (2007) is also available for free download, but you need to register and fill out a questionnaire.
Nanomedicine Volume I: Basic Capabilities by Robert A. Freitas. A detailed technical examination of nanotechnology applied to medicine.
Nanomedicine Volume IIA: Biocompatibility by Robert A. Freitas. A detailed look at potential responses of the human body to the introduction of artificial medical nanodevices.
The Prospect of Immortality by Robert Ettinger. The book that started the cryonics movement in 1964.
The Scientific Conquest of Death - Essays on Infinite Lifespans, edited by the Immortality Institute.
The First Immortal by James Halperin (MS Word document). A fictional story of a family surviving and reuniting after a century of cryopreservation.
Formerly Brandewyne by Jude Liebermann (there is a link to obtain a PDF file). A fictional story of a middle-aged executive waking as a young woman in 2078 after a "fatal" car accident in 1999.

Alla mainitut julkaisut eivät ole välttämättä vapaasti saatavilla. Voit kysellä niitä esim. Helsingin yliopiston kirjastosta tai yhdistyksen tapaamisissa.

Katsausartikkeleita.

Best BP, in: Rejuvenation Research (2008 Apr;11(2)), "Scientific justification of cryonics practice". pg. 493-503. PDF here.
Paynter SJ, in Brain Res Bull. (2008 Jan 31;75(1)) "Principles and practical issues for cryopreservation of nerve cells". pg. 1-14.

Merkittäviä julkaisuja.

Ensimmäinen artikkeli, jossa kuvataan kaniinin munuaisen jäähdyttäminen -135 °C:een ja sen toimiminen sulatuksen jälkeen eläimen ainoana munuaisena. Fahy GM, Wowk B, Pagotan R, Chang A, Phan J, Thomson B, Phan L, "Physical and biological aspects of renal vitrification", in: Organogenesis (2009 vol. 5), pg. 167-175.
Kryoniikan etiikasta. Shaw David, in Bioethics (2009 Nov; 23 (9)) "Cryoethics: seeking life after death". pg. 515-521.
First paper showing recovery of brain electrical activity after freezing to -20°C. Suda I, Kito K, Adachi C, in: Nature (1966, vol. 212), "Viability of long term frozen cat brain in vitro", pg. 268-270.
First demonstration that both the viability and structure of complex neural networks can be well preserved by vitrification: Pichugin Y, Fahy GM, Morin R, in: Cryobiology, (2006, vol. 52), "Cryopreservation of rat hippocampal slices by vitrification", pg. 228-240. PDF here.
First paper showing good ultrastructure of vitrified/rewarmed mammalian brains and the reversibility of prolonged warm ischemic injury in dogs without subsequent neurological deficits, and setting forth the present scientific evidence in support of cryonics: Lemler J, Harris SB, Platt C, Huffman T, in: Annals of the New York Academy of Sciences, (2004 vol. 1019), “The Arrest of Biological Time as a Bridge to Engineered Negligible Senescence", pg. 559-563.
First discussion of cryonics in a major medical journal: Whetstine L, Streat S, Darwin M, Crippen D, in: Critical Care, (2005, vol. 9), "Pro/con ethics debate: When is dead really dead?", in press.

First paper to propose cryonics by neuropreservation: Martin G, in: Perspectives in Biology and Medicine (1971, vol. 14), “Brief proposal on immortality: an interim solution”, pg. 339.
First paper showing recovery of a mammalian organ after cooling to -196°C (liquid nitrogen temperature) and subsequent transplantation: Hamilton R, Holst HI, Lehr HB, in: Journal of Surgical Research (1973, vol 14), "Successful preservation of canine small intestine by freezing", pg. 527-531.
First paper showing partial recovery of brain electrical activity after 7 years of frozen storage: Suda I, Kito K, Adachi C, in: Brain Research (1974, vol. 70), “Bioelectric discharges of isolated cat brain after revival from years of frozen storage", pg. 527-531.
First paper suggesting that nanotechnology could reverse freezing injury: Drexler KE, in: Proceedings of the National Academy of Sciences (1981, vol. 78), "Molecular engineering: An approach to the development of general capabilities for molecular manipulation", pg. 5275-5278.
First paper showing that large organs can be cryopreserved without structural damage from ice: Fahy GM, MacFarlane DR, Angell CA, Meryman HT, in: Cryobiology (1984, vol. 21), "Vitrification as an approach to cryopreservation", pg. 407-426.
First paper showing that dogs can be recovered after three hours of total circulatory arrest (“clinical death”) at 0°C (32°F). This supports the reversibility of the hypothermic phase of cryonics: Haneda K, Thomas R, Sands MP, Breazeale DG, Dillard DH, in: Cryobiology (1986, vol. 23), "Whole body protection during three hours of total circulatory arrest: an experimental study", pg. 483-494.
First detailed discussion of the application of nanotechnology to reverse human cryopreservation: Merkle RC, in: Medical Hypotheses (1992, vol. 39), "The technical feasibility of cryonics", pg. 6-16.
First successful application of vitrification to a relatively large tissue of medical interest: Song YC, Khirabadi BS, Lightfoot F, Brockbank KG, Taylor MJ, in: Nature Biotechnology (2000, vol. 18), "Vitreous cryopreservation maintains the function of vascular grafts", pg. 296-299.
First report of the consistent survival of transplanted kidneys after cooling to and rewarming from -45°C: Fahy GM, Wowk B, Wu J, Phan J, Rasch C, Chang A, Zendejas E, in: Cryobiology (2004 vol. 48), "Cryopreservation of organs by vitrification: perspectives and recent advances", pg. 157-78.
Rigorous demonstration of memory retention following profound hypothermia, confirming theoretical expectation and clinical experience. Alam HB, Bowyer MW, Koustova E, Gushchin V, Anderson D, Stanton K, Kreishman P, Cryer CM, Hancock T, Rhee P, in: Surgery (2002, vol. 132), "Learning and memory is preserved after induced asanguineous hyperkalemic hypothermic arrest in a swine model of traumatic exsanguination", pg. 278-88.