Publications

2019

Gabelica, V.; Shvartsburg, A. A.; Afonso, C.; Barran, P.; ... Kim, H. I.; ...; Valentine, S. J.; Wyttenbach T. "Recommendations for reporting ion mobility Mass Spectrometry measurements" Mass. Spectrom. Rev., 2019, in press., (doi: 10.1002/mas.21585)

Choi, T. S.; Seo, J.; Kim, H. I.;"IM-MS for Supramolecular Systems: Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase" Comprehensive Analytical Chemistry, 2019, 83, 197-236.

2018

Lee, S.-S.; Lee, J.-U.; Oh, J. H.; Park, S.; Hong, Y.; Min, B. K.; Lee, H. H. L.; Kim, H. I.; Kong, X.; Lee, S.; Oh, H. B. "Chiral differentiation of D and L-isoleucine using permethylated β-cyclodextrin: infrared multiple photon dissociation spectroscopy, ion-mobility mass spectrometry, and DFT calculations" Phys. Chem. Chem. Phys. 2018, 20, 30428-30436.

Lee, H. H. L.; Heo, C. E.; Seo, N; Yun, S. G.; An, H. J.; Kim, H. I. "Accurate Quantification of N-glycolylneuraminic Acid in Therapeutic Proteins Using Supramolecular Mass Spectrometry" J. Am. Chem. Soc., 2018, 140, 16528-16534.

Wongkongkathep, P.; Han, J. Y.; Choi, T. S.; Yin, S.; Kim, H. I.; Loo, J. A. "Native Top-Down Mass Spectrometry and Ion Mobility MS for Characterizing the Cobalt and Manganese Metal Binding of α-Synuclein Protein" J. Am.Soc. Mass Spectrom. 2018, 29, 1870-1880.

Lee, J. W.; Lee, H. H. L.; Davidson, K. L.; Bush, M. F.; Kim, H. I. "Structural Characterization of Small Molecular Ions by Ion Mobility Mass Spectrometry in Nitrogen Drift Gas: Improving the Accuracy of Trajectory Method Calculations" Analyst, 2018, 143, 1786-1796

Choi, T. S.; Han, J. Y.; Heo, C. E.; Lee, S. W.; Kim, H. I. "Electrostatic and hydrophobic interactions of lipid-associated α-synuclein: The role of a water-limited interfaces in amyloid fibrillation" BBA-biomembr., 2018, 1890, 1854-1862

Heo, C. E.; Choi, T. S.; Kim, H. I. "Competitive Homo- and Hetero- Self-assembly of Amyloid-β 1-42 and 1-40 in the Early Stage of Fibrillation" Int. J. Mass. Spectrom., 2018, 428, 15-21

Choi, T. S.; Lee, J. Y.; Han, J. Y.; Jeong, B. C.; Wongkongkathep, P.; Loo, J. A.; Lee, M. J.; Kim, H. I. "Supramolecular Modulation of Structural Polymorphism in Pathogenic α-Synuclein Fibrils Using Cu(II) Coordination" Angew. Chem. Int. Ed., 2018, 57, 3099-3103

Han, J. Y.; Choi, T. S.; Kim, H. I. "Molecular Role of Ca²⁺ and Hard Divalent Metal Cations on Accelerated Fibrillation and Interfibrillar Aggregation of α-Synuclein" Sci. Rep. 2018, 8, 1895.

2017

Lee, J. W.; Davidson, K. L.; Bush, M. F.; Kim, H. I. "Collision Cross Sections and Ion Structures: Development of a General Calculation Method via High-quality Ion Mobility Measurements and Theoretical Modeling" Analyst, 2017, 142, 4289-4298

Choi, T. S.; Lee, H. J.; Han, J. Y.; Lim, M. H.; Kim, H. I. "Molecular Insights into Human Serum Albumin as a Receptor of Amyloid-β in the Extracellular Region" J. Am. Chem. Soc., 2017, 139, 15437-15445.

Lee, H. H. L.; Kim, H. I. "Supramolecular Analysis of Monosaccharide Derivatives Using Cucurbit[7]uril and Electrospray Ionization Tandem Mass Spectrometry" Isr. J. Chem., 2018, 58, 472-478.

Choi, T. S.; Lee, H.H.; Ko, Y. H.; Jeong, K. S.; Kim, K.; Kim, H. I. "Nanoscale Control of Amyloid Self-Assembly Using Protein Phase Transfer by Host-Guest Chemistry" Sci. Rep., 2017, 7, 5710.

Hong, A.; Lee, H. H.; Heo, C. E.; Cho, Y.; Kim, S.; Kang. D.; Kim, H. I. "Distinct Fragmentation Pathways of Anticancer Drugs Induced by Charge-Carrying Cations in the Gas Phase" J. Am. Soc. Mass Spectrom. 2017, 28, 628-637.

2016

Jang, I.; Lee, S. Y.; Hwangbo, S.; Lee, H. K.; Kim, H. I.; Kang, D. J.; Moon, B. J.; Oh, H. B. "TEMPO-assisted free radical initiated peptide sequencing mass spectrometry (FRIPS MS) in Q-TOF and orbitrap mass spectrometers: single-step peptide backbone dissociations" J. Am. Soc. Mass Spectrom. 2016, 28, 154-163

Han, J.Y.; Choi, T. S.; Kim, S.; Lee, J. W.; Ha, Y.; Jeong, K. S.; Kim, H.; Choi, H. C.; Kim, H. I. "Probing Distinct Fullerene Formation Processes from Carbon Precursors of Different Sizes and Structures" Anal. Chem. 2016, 88, 8232-8238.

Kim, K.T.; Choi, T. S.; Kim, K. Y.; Kim, H. I.; Kim, B. H. "Disassembly of Chromophore-Guided DNA Duplexes Through Site-Selective Binding of Coralyne to Pyrene-Modified Adenine Bases " ChemPlusChem 2016, 81, 590-593.

Lee, S.J. C.#; Choi, T. S.#; Lee, J. W.#; Lee, H. J.; Mun, D.-G.; Akashi, S.; Lee, S.-W.; Lim, M. H.; Kim, H. I. "Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper" Chem. Sci. 2016, 7, 5398-5406. #Authors with equal contribution

Lee, H. H. L.; Lee, J. W.; Jang, Y.; Ko, Y. H.; Kim, K.; Kim, H. I. "Manifesting Subtle Differences of Neutral Hydrophilic Guest Isomers in a Molecular Container by Phase Transfer" Angew. Chem. Int. Ed. 2016, 55, 8249-8253.

Lee, J. W.; Park, M. H.; Ju. J. T.; Choi, Y. S.; Hwang, S. M.; Jung, D. J.; Kim, H. I. "Stabilization of Compact Protein Structures by Macrocyclic Hosts Cucurbit[n]urils in the Gas Phase" Mass Spectrom. Lett. 2016, 7, 16-20.

Lee, H. H.; Hong, A.; Cho, Y.; Kim, S.; Kim, W. J.; Kim, H. I. "Structural Characterization of Anticancer Drug Paclitaxel and Its Metabolites Using Ion Mobility Mass Spectrometry and Tandem Mass Spectrometry" J. Am. Soc. Mass Spectrom. 2016,27, 329-338.

2015

Lee, J. W.#; Shin, M. H.#; Mobley, W.; Urbach, A. R.; Kim, H. I. "Supramolecular Enhancement of Protein Analysis via the Recognition of Phenylalanine with Cucurbit[7]uril" J. Am. Chem. Soc. 2015, 137, 15322-15329. #Authors with equal contribution

Lee, J. W.; Kim, H. I. "Solvent-Induced Structural Transitions of Lysozyme in an Electrospray Ionization Source" Analyst 2015, 140, 3573-3580.

Lee, J. W.#; Lee, H. H. L.#; Ko, Y. H.; Kim, K.; Kim, H. I. "Deciphering the Specific High-Affinity Binding of Cucurbit[7]uril to Amino Acids in Water" J. Phys. Chem. B 2015, 119, 4628-4636. #Authors with equal contribution

Lee, J.; Park, J.; Lee, H. H.; Park, H.; Kim, H. I.; Kim, W. J. "Fluorescence Switch for Silver Ion Detection Utilizing Dimerization of DNA-Ag Nanoclusters" Biosens. Bioelectron. 2015, 68, 642-647.

Lee, J. W.; Kim, H. I. "Investigating Acid-Induced Structural Transitions of Lysozyme in an Electrospray Ionization Source" Analyst 2015,140, 661-669.

2014

Choi, T. S.; Lee, J. W.; Jin, K. S.; Kim, H. I. "Amyloid Fibrillation of Insulin under Water-limited Condition" Biophys. J. 2014, 107, 1939-1949.

Kim, K.; Lee, J. W.; Chang, T.; Kim, H. I. "Characterization of Polylactides with Different Stereoregularity Using Electrospray Ionization Ion Mobility Mass Spectrometry" J. Am. Soc. Mass Spectrom. 2014, 25, 1771-1779.

Lee, H. H.#;Choi, T. S.#; Lee, S. J. C.; Lee, J. W.; Park, J.; Ko, Y. H.; Kim, W. J.; Kim, K.; Kim, H. I. " Supramolecular Inhibition of Amyloid Fibrillation by Cucurbit[7]uril" Angew. Chem. Int. Ed. 2014, 53, 7461-7465. Highlighted on the inside back cover. #Authors with equal contribution

Ahmed , A.; Cho , Y.; Riches , E.; , Giles , K.; Lee, J. W.; Kim , H. I. ; Choi , C. H.; Kim, S. " Elucidating molecular structures of non-alkylated and short-chain alkyl (n<5, (CH2)n) aromatic compounds in crude oils by a combination of ion mobility and ultrahigh-resolution mass spectrometries and theoretical collisional cross-section calculations" Anal. Chem. 2014, 86, 3300-3307.

Lee , J.; Park, J.; Lee, H. H.; Kim, H. I. ; Kim, W. J. "DNA-templated silver nanoclusters as label-free, sensitive detection probes for potassium ion and nitric oxide" J. Mater. Chem. B 2014, 2, 2616-2621.

Lee, S. J. C.; Lee, J. W.; Choi, T. S.; Jin, K. S.; Lee, S.; Ban, C.; Kim, H. I. "Probing Conformational Change of Intrinsically Disordered α-Synuclein to Helical Structures by Distinctive Regional Interactions with Lipid Membranes" Anal. Chem. 2014, 86, 1909–1916.

Litwińczuk, A; Ryu, S. R.; Nafie, L. A.; Lee, J. W.; Kim, H. I. ; Jung, Y. M.; Czarnik-Matusewicz, B. "The Transition from the Native to the Acid-state Characterized by Multi-spectroscopy Approach: Study for the Holo-form Bovine Alpha-lactalbumin" BBA Proteins and Proteomics, 2014, 1844, 593-606.

Noh, D. H.; Lee, S. J. C.; Lee, J. W.; Kim, H. I. "Host-Guest Chemistry in the Gas Phase: Complex Formation of Cucurbit[6]uril with Proton-bound Water Dimer" J. Am. Soc. Mass Spectrom. 2014, 25, 410-421.

2013

Lee, J.; Park, H.; Kwon, H.; Kwon, G.; Jeon, A.; Kim, H. I. ; Sung, B. J.; Moon, B.; Oh, H. B. "One-Step Peptide Backbone Dissociations in Negative-Ion Free Radical Initiated Peptide Sequencing (FRIPS) Mass Spectrometry" Anal. Chem. 2013, 85, 7044-7051.

Lee, S. J. C; Lee, J. W.; Lee, H. H.; Seo, J.; Noh, D. H.; Ko, Y. H.; Kim, K.; Kim, H. I. "Host-Guest Chemistry from Solution to the Gas Phase: An Essential Role of Direct Interaction with Water for High-Affinity Binding of Cucurbit[n]urils" J. Phys. Chem. B 2013, 117, 8855-8864.

Lee, J. W.#; Heo, S. W.#; Lee, S. J. C.; Ko, J. Y.; Kim, H.; Kim, H. I. "Probing Conformational Changes of Ubiquitin by Host-Guest Chemistry Using Electrospray Ionization Mass Spectrometry" J. Am. Soc. Mass Spectrom. 2013, 24, 21-29. #Authors with equal contribution

2012

Shin, Y. S.; Choi, T. S.; Kim, H.; Beauchamp, J. L.; Heath, J. R.; Kim, H. I. "'A Microfluidic Based Bubble Generation Enables Analysis of Physical Property Change in Phospholipid Surfactant Layers by Interfacial Ozone Reaction" Lab. Chip, 2012, 12, 5243-5248.

Choi, T. S.; Ko, J. Y.; Heo, S. W.; Ko, Y. H.; Kim, K. M.; Kim, H. I. "Unusual Complex Formation and Chemical Reaction of Haloacetate Anion on the Exterior Surface of Cucurbit[6]uril in the Gas-phase" J. Am. Soc. Mass Spectrom. 2012, 23, 1786-1793.

Campuzano, I. D. G.; Bush, M. F.; Robinson, C. V.; Beaumont, C.; Richardson, K.; Kim, H.; Kim, H. I. "Structural Characterization of Drug-like Compounds by Ion Mobility Mass Spectrometry: Comparison of Theoretical and Experimentally Derived Nitrogen Collision Cross-sections" Anal. Chem. 2012, 84, 1026-1033.

Ko, J. Y.; Choi, S. M.; Rhee, Y. M.; Beauchamp, J. L.; Kim, H. I. "Studying Interfacial Reactions of Cholesterol Sulfate in an Unsaturated Phosphatidylglycerol Layer with Ozone Using Field Induced Droplet Ionization Mass Spectrometry" J. Am. Soc. Mass Spectrom. 2012,23, 141-152.

2011

Ko, J. Y.; Heo, S. W.; Lee, J.; Oh, H.; Kim, H.; Kim, H. I. "Host-Guest Chemistry in the Gas Phase: Complex Formation with 18-Crown-6 Enhances Helicity of Alanine-Based Peptides" J. Phys.Chem. A 2011, 115, 14215-14220.

Heo, S. W.; Choi, T. S.; Park, K. M.; Ko, Y. H.; Kim, S. B.; Kim, K.; Kim, H. I. "Host-Guest Chemistry in the Gas Phase: Selected Fragmentations of CB[6]-Peptide Complexes at Lysine Residue and Its Utility to Pobe the Structures of Small Proteins" Anal. Chem.2011, 83, 7916-7923.

Sokol, E.; Noll, R. J.; Cooks R. G.; Beegle L. W.; Kim, H. I. ; Kanik, I. “Miniature mass spectrometer equipped with electrospray and desorption electrospray ionization for direct analysis of organics from solids and solutions" Int. J. Mass Spectrom. 2011, 306, 187-195.

2010

Kim, H. I. ; Kim, H.; Shin, Y.; Beegle, L. W.; Heath, J. R.; Goddard, W. A.; Kanik, I.; Beauchamp, J. L. “Time Resolved Studies of Interfacial Reactions of Ozone with Pulmonary Phospholipid Surfactants Using Field Induced Droplet Ionization Mass Spectrometry,” J. Phys. Chem. B 2010, 114, 9496-503.

Kim, H. I. ; Kim, H.; Shin, Y.; Neidholdt, E. L.; Beegle, L. W.; Jang, S.; Heath, J. R.; Goddard, W. A.; Kanik, I.; Beauchamp, J. L. “Interfacial Reaction of Ozone with Surfactant Protein B in Model Surfactant System,” J. Am. Chem. Soc. 2010, 132, 2254-2263.

Before 2010

Kim, H. I.; Kim, H.; Pang, E.; Ryu, E. K.; Beegle, L. W.; Loo, J. A.; Kanik, I. “Structural Characterization of Unsaturated Phosphatidylcholines Using Traveling Wave Ion Mobility Spectrometry in N2” Anal. Chem. 2009, 81, 8289-8297.

Kim, H. I. ; Beauchamp, J. L. *“The Route 66 Method for Locating Disulfide Bonds in Peptides: Selective Cleavages of S-C Bonds Initiated with an Alkali and Alkaline Earth Metal Enolate Complexes at Cysteine” J. Am. Soc. Mass. Spectrom. 2009, 20, 157-166. *J. Am. Soc. Mass Spectrom. Jan. Issue Cover Article

Kim, H*; Kim, H. I.*; Beegle, L. W.; Johnson, P. V.; Beauchamp, J. L.; Goddard, W. A.; Kanik, I. “An Experimental and Theoretical Investigation into the Correlation between Mass and Ion Mobility for Choline and Other Ammonium Cations in N2” Anal. Chem. 2008,80, 1928-1936. *Authors with Equal Contribution.

Kim, H. I. ; Beauchamp, J. L. “Identifying the Presence of a Disulfide Linkage in Peptides by the Selective Elimination of Hydrogen Disulfide from Collisionally Activated Alkali and Alkaline Earth Metal Complexes” J. Am. Chem. Soc. 2008, 130, 1245-1257.

Kim, H. I. ; Beauchamp, J. L. “Cluster Phase Chemistry: Collisions of Vibrationally Excited Cationic Dicarboxylic Acid Clusters with Water Molecules Initiate Dissociation of Cluster Components” J. Phys. Chem. A 2007, 111, 5954-5967.

Johnson, P. V.; Beegle, L. W.; Kim, H. I. ; Eiceman, G. A.; Kanik, I, “Ion Mobility Spectrometry in Space Exploration; A Review Article” Int. J. Mass. Spectrom. 2006, 262, 1-15.

Kim, H. I. ; Goddard, W. A.; Beauchamp, J. L. “Cluster Phase Chemistry: Anionic Sodium Salts of Dicarboxylic Acid Clusters with Water Molecules” J. Phys. Chem. A 2006, 110, 7777-7786.

Kim, H. I. ; Johnson, P. V.; Beegle, L. W.; Beauchamp, J. L.; Kanik, I. “Electrospray ionization ion mobility spectrometry of carboxylate anions: Ion mobilities and a mass-mobility correlation” J. Phys. Chem. A 2005, 109, 7888-7895.

Johnson, P. V.; Kim, H. I. ; Beegle L. W.; Kanik I. “Electrospray ionization ion mobility spectrometry of amino acids: Ion mobilities and a mass-mobility correlation” J. Phys. Chem. A 2004, 108, 5785-5792.