Who?

Dr Fabien JOURDAN

INRAE research scientist (DR2)

PhD in Computer Science, Habitation (HDR)

Director of MetaboHUB

Metabolomics Society secretary

Where?

INRAE UMR1331 Toxalim

180 chemin de Tournefeuille St-Martin-du-Touch

BP 3 31931 TOULOUSE CEDEX France

- way to the lab -

Get in touch?

Mail: Fabien.Jourdan-at-inrae.fr

Tel - +33 (0)5 82 06 63 95 -

Orcid: orcid.org/0000-0001-9401-2894

Site: http://sites.google.com/site/fabienjourdan/

twitter: @metexplore

Research interests

Food toxicology: some food contaminants, like Bipshenol A, may have impact on Human Health. Our aim is to study potential metabolic effects according to different doses and during critical Human development phases (e.g. pregnancy).

Bioinformatics: developing methods to study genome-scale metabolic networks. These approaches are mainly based on graph models and constraint based models (e.g. FBA). The aim is to use experimental data like metabolomics ones in order to retrieve parts of the organism metabolism affected by genetic or environmental perturbations.

Keywords: metabolic networks, metabolomics, information visualization, food toxicology

www.metabohub.fr

Seleced publications

  • Pablo Rodríguez-Mier, Nathalie Poupin, Carlo de Blasio, Laurent Le Cam, Fabien Jourdan (2021). DEXOM: Diversity-based enumeration of optimal context-specific metabolic networks. PLoS Computational Biology 17(2):e1008730. doi: 10.1371/journal.pcbi.1008730, https://hal.archives-ouvertes.fr/hal-03154775v1. [IF: 4.475, MATHEMATICAL & COMPUTATIONAL BIOLOGY, Q1, 7/66]

  • Nathalie Poupin, Florence Vinson, Arthur Moreau, Aurélie Batut, Maxime Chazalviel, Benoit Colsch, Laetitia Fouillen, Sarah Guez, Spiro Khoury, Jessica Dalloux-Chioccioli, Anthony Tournadre, Pauline Le Faouder, Corinne Pouyet, Pierre Van Delft, Fanny Viars, Justine Bertrand Miche and Fabien Jourdan. (2020). Improving lipid mapping in Genome Scale Metabolic Networks using ontologies. Metabolomics. 16(4):44, https://dx.doi.org/10.1007/s11306-020-01663-5, https://hal.archives-ouvertes.fr/hal-02935172 [IF: 4.290, ENDOCRINOLOGY & METABOLISM, Q2, 60/145]

  • Clément Frainay, Sandrine Aros, Maxime Chazalviel, Thomas Garcia, Florence Vinson, Nicolas Weiss, Benoit Colsch, Frédéric Sedel, Dominique Thabut, Christophe Junot and Fabien Jourdan (2019). MetaboRank: network-based recommendation system to interpret and enrich metabolomics results. Bioinformatics, 35 (2), 274-283, https://dx.doi.org/10.1093/bioinformatics/bty577, https://hal.inrae.fr/hal-02627792 [IF: 6.937, MATHEMATICAL & COMPUTATIONAL BIOLOGY, Q1, 3/58]

  • Maxime Chazalviel, Clément Frainay, Nathalie Poupin, Florence Vinson, Benjamin Merlet, Benjamin Gloaguen, Ludovic Cottret and Fabien Jourdan (2018). MetExploreViz: web component for interactive metabolic network visualization. Bioinformatics, 34 (2), 312-313, https://dx.doi.org/10.1093/bioinformatics/btx588, https://hal.inrae.fr/hal-02621786 [IF: 6.937, MATHEMATICAL & COMPUTATIONAL BIOLOGY, Q1, 3/58]

  • Ludovic Cottret, Clément Frainay, Maxime Chazalviel, Floréal Cabanettes, Yoann Gloaguen, Etienne Camenen, Benjamin Merlet, Stephanie Heux, Jean-Charles Portais, Nathalie Poupin, Florence Vinson and Fabien Jourdan (2018). MetExplore: collaborative edition and exploration of metabolic networks. Nucleic Acids Research, 46 (W1), 8 p., https://dx.doi.org/10.1093/nar/gky301, https://hal.inrae.fr/hal-01886470 [IF: 16.971, BIOCHEMISTRY & MOLECULAR BIOLOGY, Q1, 4/300]

Ongoing international projects

  • ANR-DFG MetCalssNet (Coordinator) : 2020-2023. Title : New approaches to bridge the gap between genome-scale metabolic networks and untargeted metabolomics. Total funding : 928 k€

  • H2020 SAFFI (Partner) : 2020-2024 Title : Safe Food for Infants in China and the EU. Coordinatorr : Erwan Engel (INRAE, France). Total funding : 6,752 k€

  • H2020 GOLIATH (Partner, WP leader) : 2019-2023. Title : GOLIATH Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds. Coordinator : Pr. Juliette Legler (University of Utrecht, NL). Total funding : 6,761 k€.

Ongoing projects national projects

  • PIA equipex+, ANR MetEx+ (Coordinator) : 2021-2025. Title: Next generation metabolomics and fluxomics, from population to single cell. Consortium : MetaboHUB. Total funding: 5,675 k€.

  • PIA 3, ANR MetaboHUB 2.0 (Coordinator) : 2020-2024 Title: National metabolomics and fluxomics infrastructure. Consortium : MetaboHUB. Total funding : 2,900 k€.

  • ADEM Metalisabet (Partner, WP leader) : 2021-2024 Titre: Évaluation de l’impact métabolique de l’exposition environnementale, résidentielle et professionnelle aux polluants : une approche métabolomique. Coordinator : Luc Dauchet (Institut Pasteur, Lille). Total funding : 170 k€.

  • ANSES ToxMining (Coordinator) : 2019-2022. Title: Predictive toxicology approach for prioritizing the assessment of chemical agents. Total funding : 197 k€.

  • ANR Sentinel (Partner) : 2020-2023 Title: High-throughput screening tools for a reinforced chemical safety surveillance of food. Coordinator: Erwan Engel (INRAE, France). Total funding : 596 k€.

  • INCA MDM2 (Partenaire, WP leader) : 2019-2023. Title: MDM2 and serine metabolism: New therapeutic targets for liposarcomas. Coordinator: Dr Laetitia Linares (INSERM, Montpellier). Total funding : 592 k€.

  • INCA METAhCol (Partner) : 2017-2021. Title: Impact of low doses mixtures of aromatic hydrocarbon on colon carcinogenesis process : focus on energy metabolism hallmark. Coordinator: Dominique Lagadic- (INSERM, Rennes). Total funding: 657 k€

Other stuffs

  • Cycling

  • Scuba diving

  • Golfing

  • Windsurfing (not kitesurfing yet!)

  • Visiting the world ... if we can