Research fellow at INRIA Paris, team MUSCLEES
Applied Mathematics, Modeling of complex biological systems
Email : diane.a.peurichard@inria.fr
Office: Sorbonne Université
Laboratoire Jacques-Louis Lions, 16-26.324
4, place Jussieu, F75252 Paris Cedex 05
I am a research fellow at INRIA Paris in the team MUSCLEES (Multiscale Understanding across Scales of Complex Living Ecosystems with Emerging Structures).
I am interested in the mathematical modelling of biological systems and particularly in complex systems which develop self-organized dynamics. My methods combine analysis, asymptotic theory and multiscale numerical techniques. My research focuses on (i) the development and validation of (microscopic) agent-based models for biological applications (such as tissue morphogenesis, regeneration, wound healing, collective cell dynamics), (ii) the micro- macro- passage in models of complex systems, to establish the link between PDE and agent-based models using tools from kinetic theory.
see Scientific interests for more details
Upcoming conferences
September 29- october 3, 2025: Round Mean-field IV: Nbody sul canal grande, Venise, Italy, https://indico.math.cnrs.fr/event/14152/
News
Our paper 'From a nonlinear kinetic equation to a volume-exclusion chemotaxis model via asymptotic preserving methods' with X. Ruan and G. Estrada Rodriguez has been published in KRM! link
Our paper 'A computational model reveals an early transient decrease in fiber cross-linking that unlocks adult regeneration' with A. Pacary, L. Vaysse, P. Monsarrat, C. Bolut, A. Girel, C. Guissard, A. Lorsignol, V. Planat-Benard, J. Paupert, M. Ousset & L. Casteilla has been published in NPJ Regenerative Medicine! link
Mathematical modeling of complex systems coming from biology, microscopic models, derivation of macroscopic models, kinetic theory, Asymptotic study
From Oct 2015 to Oct 2017 I was a post doctoral researcher in applied mathematics at the faculty of mathematics in Vienna with Christian Schmeiser. We were interested in modelling the morphology and mechanics of cells crawling, the motion of which being driven by cytoskeletal dynamics. I am a former member of the Project WWTF (Modeling of Polarization and Motility of Leukocytes in Three-Dimensional Environments).
From september 2012 to august 2015, I was a PhD student in applied mathematics at Institut de Mathématiques de Toulouse (IMT) under the supervision of Pierre Degond and Fanny Delebecque. We worked in collaboration with two biologists: Louis Casteilla and Anne Lorsignol from the STROMALAB. We were interested in the modelling of adipose tissue homeostasis and I was a member of the CNRS project PEPS-MATH (Modeling Adult Tissue Homeostasis) and the project was supported by the Region Midi Pyrenees under grant APRTCN 2013.
Students:
Hiroshi Hori: Post-doc (since june 2024) on the modeling of bacteria micro-colonies. Co-supervision with S. Hecht
Suney Toste: Post-doc (january 2024 - may 2025) on the modeling of Adipose Tissue metabolism
Pauline Chassonnery : PhD student (2020-2023) in co-direction with L. Casteilla (RESTORE, Toulouse): 3D modelling of Adipose Tissues. Defended on december 19th, 2023, link
Rudio Fida Cyrille: Internship (2022). Modeling of bacteria colonies
Sara Moussaoui: TER (2022) Modélisation de particules en interaction
Agathe Yvinec-Tolmer: Internship (2021) with N. Pouradier Duteil . Modélisation multi-échelle de particules en interaction
Xinran Ruan: Post-doc (2020-2021). Volume-filling Keller-Segel models
Valeria Caliaro: PhD student (2019-2022) in co-direction with O. Chara. Mathematical modelling of Axolotl Regeneration
Sophie Hecht: Post-doc (2019-2021) in co-supervision with Marie Doumic. Modelling of early-morphogenesis of rod-shaped bacteria
Gissell-Estrada Rodriguez: Post-doc (2019-2020) in co-supervision with Luis Almeida. Modelling of Glioblastoma
Loïs Naudin: Internship (2018)with J. Clairambault 'Modelling the energetic metabolism in tumours'
Shen Zhenyu: Internship (2018) 'Coarse-graining of swimmer dynamics in a fluid filled with obstacles'
Research networks:
RESTORE, Toulouse, long-lasting collaboration on tissue homeostasis and regeneration
SysBio Group/ Technische University Dresden, Germany in the frame of Valeria Caliaro PhD (supervision with O. Chara)
WPI (University of Vienna) in the frame of the associated team 'Mathematical Modelling of Cell Motility and Autophagy' (MaMoCeMa) with M. Doumic, C. Schmeiser
HTE Program 'Modeling of Glioblastoma treatment-induced resistance and heterogeneity by multi-modal imaging' (MoGlimaging) principal investigator: COHEN-JONATHAN MOYAL
INRIA-WPI (Vienna) associated team 'Mathematical Modelling of Cell Motility and Autophagy' (MaMoCeMa) with M. Doumic, C. Schmeiser
FSMP Ambassadeur-PGSM for Austria
Talk at Journées Scientifiques Inria, Lyon june 2019 https://www.youtube.com/watch?v=S663qjHdoFw&t=97s
Talk at IMPA, Rio de Janeiro, Brazil, nov 2018 https://www.youtube.com/watch?v=SPeiCewo5ks
Talk at CEMRACS 2018, Marseille, july 2018 https://www.youtube.com/watch?v=O50CkT8n_8I&t=563s
Talk at CMM-Fields-Inria Workshop on Mathematics for Medicine, january 2018, http://www.fields.utoronto.ca/video-archive/static/2018/02/2422-18056/mergedvideo.ogv