Recent Textbooks
Here is a list of my recent textbooks:
1. Cardiac Perfusion and Pumping (World Scientific, 2006):
Physiomics of Coronary Perfusion and Cardiac Pumping; Quantification of Cardiac Perfusion and Function Using Nuclear Cardiac Imaging; Perfusion Depiction by SPECT Imaging, Computation of Blood Flow Pressure and Velocity Patterns Within Myocardial Regions; Left Ventricular (LV) Pressure Increase Mechanism During Isovolumic Contraction, and Determination of the Equivalent LV Myocardial Fibers Orientation; New Clinically Relevant Left Ventricular Contractility Index (based on Normalized Wall Stress); Augmented Myocardial Perfusion by Coronary Bypass Surgical Procedure: Emphasizing Flow and Shear Stress Analysis at Proximal and Distal Anastomotic Sites.
https://drive.google.com/file/d/1VspEo59KVuQgLjwk3KFCUk4oMeQRDYV3/view?usp=sharing
2. Applied Biomedical Engineering Mechanics (CRC Press, Taylor and Francis, 2009):
Uses a problem-based approach to quantify physiological processes, formulate diagnostic and interventional procedures, develop orthopedic surgical procedures, and analyze sports games to maximize competency.
Features: Incorporates material from solid mechanics, fluid mechanics, dynamics and vibrations, control systems, and mathematical modeling; Provides biomechanical guidelines for internal fixation of bone and spinal fractures as well as the treatment of herniated discs; Presents the mechanics of heart function, heart structures, noninvasive determination of aortic pressure, and characterization of left-ventricular afterload; Discusses detection of infarcted myocardial segments; Assesses the constitutive properties and degeneration of heart valves; Covers the modeling of lung ventilation, its application to lung disease diagnosis, lung gas-transfer mechanism, and indices to assess its performance; Examines how human anatomical structures and physiological processes are designed for optimal functionality.
https://drive.google.com/open?id=0BzOPlHbjWLYta3djeFV0MkRaMXc
3. Socio-economic Democracy and the World Government (World Scientific, 2004):
Serves as a valuable teaching, learning, knowledge and research resource for a holistic approach to a sustainable living environment promoting collective welfare, based on the formation of autonomous functionally-sustainable communities (FSCs). Within the FSCs, all the business corporations would be structured as cooperatives, wherein all the corporation staff would jointly own the shares of the corporation and hence be joint owners of the corporation. In this
way, the collective wealth of each FSC would be jointly owned by its people more proportionately. The FSCs would have a People’s Participatory Democratic System (PPDS) of governance , whereby the most qualified representatives of all the functional sectors of the community get elected to the local Legislature. The FSCs in each region would be structured into regional economic zones (REZs), to promote trade among the region’s FSCs, and hence promote balanced economic development within each REZ. This system of FSCs and REZs would come under the aegis of a democratically structured World Parliament comprising of elected representatives of FSCs, over-seeing the development of a comprehensive charter of human rights and social justice for all the people of the world. This would enable unification of all the FSCs of the world into one global union, with all them retaining their governance autonomy. The 2004 book was in fact far ahead of its time, as it provides solution pathway for the Occupy Financial Districts movements and the present day debilitating dictatorial democratic system.
https://drive.google.com/open?id=0BzOPlHbjWLYtUl93UTNRLTZIUkE
4. Biomedical Science, Engineering and Technology (InTech Publishers, 2012):
Cohesively integrates biomedical science (disease pathways, models and treatment mechanisms), biomaterials and implants, biomedical engineering, biotechnology, physiological engineering, and hospital management science and technology. Together, these topics are providing a pathway for incorporation of STEM into medical knowhow, procedures, and devices, towards a higher order of translational medicine applied in tertiary patient care.
Biomedical Science, Engineering and Technology, by Dhanjoo N. Ghista
Chapter 35. Physiological Nondimensional Indices in Medical Assessment: For Quantifying Physiological Systems and Analysing Medical Tests’ Data https://drive.google.com/open?id=0BzOPlHbjWLYtZ08zX0Ywa0lNX1k
5. Cardiology Science and Technology (CRC Press, Taylor and Francis, 2016):
Section 1: Left Ventricular Wall Stress, Contractility and Vector Cardiogram, with Applications in Cardiology: Left ventricular Wall Stress Compendium; Assessment of Cardiac Function in Filling and Systolic Ejection Phases; Novel Cardiac Contractility Index dσ*/dt (max); Cardiomyopathy effect on Left ventricle (Shape, Wall stress and Contractility) and Improvement after Surgical Ventricular Restoration; Cardiac Contractility Measures for Left Ventricular Systolic Functional Assessment in Normal and Diseased Hearts; Analysis for Left Ventricular Pressure Increase during LV Isovolumic Contraction Phase, due to Activation of the Myocardial Fibers: Computation of LV Myocardial Wall Stresses, Myocardial Fiber Stresses and Orientation; Myocardial Infarct Induced Left Ventricular Shape Remodeling, and Surgical Ventricular Restoration to restore LV Shape and Cardiac Contractility; Vector Cardiogram Theory and Clinical Application.
Section II: ECG Signal Analysis and Cardiac Pumping (Intra-Ventricular, Aortic and Coronary Flow), with Applications in Cardiology and Cardiac Surgery: ECG and Heart Rate Variability Signal Processing and Analysis to detect Cardiac Arrhythmias; Left Ventricular Blood Pump Analysis and Outcome: Intra-LV Flow and Pressure Distributions to determine Candidacy for Coronary Bypass Surgery; Cardiac Perfusion Analysis and Quantification by Nuclear Cardiac Imaging and Computation of Intra-Myocardial Blood Flow Velocity and Pressure Patterns; Determination of Arterial Pulse Wave Propagation Velocity and Arterial Properties; Blood Flow in Patient-Specific Coronary Arteries: Causes of Atheromas at Arterial Curvatures and Bifurcations based on Hemodynamic Parameters; Intra-Left Ventricular Diastolic and Systolic Flow Distributions, based on Colour Doppler Echo Velocity Flow Mapping of Normal subjects and Heart Failure Patients; Coronary Blood Flow Analysis and Coronary Artery Bypass Graft Flow and Design; Coupled Sequential Anastomotic Bypass Graft (SABG) Design.
https://drive.google.com/file/d/1Tw2WVLElwLLIbIazb8S-GPXh8Y_hwI10/view
6. Computational and Mathematical Methods in Cardiovascular Physiology (World Scientific, 2018):
This book has literally transformed Cardiovascular Physiology into a STEM discipline, involving (i) quantitative formulations of heart anatomy and physiology, (ii) technologies for imaging the heart and blood vessels, (iii) fluid mechanics and computational analysis of blood flow in the heart, aorta and coronary arteries, (iv) design of heart valves, percutaneous valve stents, and ventricular assist devices. We will now describe the main features of the chapters of the book.
So how is this mathematically and computationally configured landscape going to impact cardiology and even cardiac surgery? We are now entering a new era of mathematical formulations of anatomy and physiology, leading to technological formulations of medical and surgical procedures towards more precision medicine and surgery. This will even entail reformatting of (i) the medical MD curriculum and courses, so as to educate and train a new generation of physicians who are conversant with medical technologies for applying into clinical care, as well as (ii) structuring of MD-PhD (Computational Medicine and Surgery) Program, to train competent medical and surgical specialists in precision medical care and patient-specific surgical care.
This book is providing a gateway for this new emerging scenario of (i) science and engineering based medical educational curriculum, and (ii) technologically oriented medical and surgical procedures. As such, this book can be usefully employed as a textbook for courses in (i) cardiovascular physiology in both the schools of engineering and medicine of universities, as well as (ii) cardiovascular engineering in biomedical engineering departments world-wide.
https://www.worldscientific.com/worldscibooks/10.1142/10996
The book provides detail biomedical engineering analyses of pancreas, lung, and kidney organ systems as well as their medical applications, for (i) precision diagnostics of diabetes, lung diseases, and kidney failure, often in the form of non-dimensional indices, and (ii) treatment systems, namely automated insulin infusion system for lowering blood glucose, hemodialysis and peritoneal dialysis.
Section I: Pancreatic System and Glucose-Insulin Regulatory System Engineering and Medical Assessment, provides rigorous analyses of (i) Pancreatic regulatory physiology, and medical assessment of pancreatic function. (ii) Detection of subjects who are diabetic and at the risk of being diabetic, based on the Oral Glucose Tolerance Test modelling of the glucose-insulin regulatory system, culminating in the formulation of Diabetes Nondimensional Index. (iii) Glucose-Insulin Control system design for lowering the glucose concentration after a meal, by application of insulin infusion based on the monitored blood glucose response. (iv) Diabetes technology for optimizing diabetes management: continuous glucose monitoring systems, smart insulin pens, insulin pumps.
Section II: Respiratory and Pulmonary System Engineering and Medical Assessment, provides in depth analyses of (i) Lung respiratory mechanics modelling to determine respiratory flow resistance and lung elastance, and lung gas transfer process modelling to determine the end-capillary O2 and CO2 partial pressures and contents. (ii) Lung ventilation modelling for development of a non-invasive ventilatory index for lung disease detection. (iii) Respiratory control system modelling to enable diffusion of O2 and CO2 across the alveolar-capillary membrane, and provide oxygenated blood to the pulmonary veins for the left atrium. (iv) Analysis of gas transfer between lung alveoli and pulmonary capillaries, and formulation of gas transfer index for clinical usage.
Section III: Renal System Engineering and Medical Assessment, provides comprehensive analyses of (i) Renal Physiology and functional assessment. (ii) Determining Kidney obstructions by Renogram data modelling, in the form of urine flow rate index. (iii) Hemodialysis and Peritoneal dialysis mechanisms and technology for kidney failure patients. (iv) Renal Regulatory Physiology Control system modelling of acid base balance and body fluid balance, useful for clinical decision making.
Key Features
• The book portrays a new format of Organ Systems Engineering, constituting Translational biomedical engineering and STEM format of medicine.
• It can serve as a textbook for upper-level undergraduate courses and graduate level courses in (i) Organ Systems Engineering in Biomedical Engineering departments, and (ii) Quantitative Physiology in Medical schools.
• It can also be employed to offer a novel MD-PhD (Biomedical Engineering) Program in Medical Schools. It can even serve as a reference for Physicians and Biomedical Engineers working in hospitals on medical assessment of pancreatic, lungs and kidney functions.
These books can be employed as course textbooks in many of the courses of the Educational Programs in Biomedical Engineering (BME), Computational Medicine and Surgery, Political Science and Economics, and MD-PhD (BME).
