A PhD studentship is availble in the group (start Sept 2024) through UCL EPSRC DTP programme. Find the details and apply here

CONGRATULAITIONS to SEONG HEUN and SILVIA for succesfully passing their VIVA ! Well done Dr Seong Heun Kim and Dr Silvia Anselmi!!

CONGRATULATIONS to MEIR for successfully passing his VIVA! Well done Dr Meir Touitou!!

Check out our new works in medicinal chemistry! new antimicrobials acting against HSV and TB

We are welcoming new entries in the Group! Dr Fei Zhao and Dr Haoyue Xiang from China, Dr Guilherme Fernandes from Brazil, and Jingyue Wu, Blazej Czemerys and Chuhan Li who are starting their PhD

Seong Heun and Dorothy Review on antimicrobial guanidines is out in Eur. J. Med. Chem.

Silvia, Siyu and Seong-Heun work on sulfoxidation reactions using CALB is now available in Org. Biomol. Chem

A new review on the biocatalytic synthesis of heterocyles by Fei and Domiziana is out in SYNTHESIS

And a book chapter on propargylamine synthesis is out in Methodologies in Amine Synthesis by Bernardi and Ricci

If you are interested in chemo-enzymatic reactions and unconventional biocatalysis, read our recent reviews published in Synthesis and ChemBioChem!

Congratulations to Kate and Silvia for their work on nitrilase biocatalysed DKR of thio-nitriles now availble on Chem. Eur. J. and to Fei and Domiziana for their work on MAO-N biocatalysed aromatization of indolines now published in ACS Catalysis.

CONGRATULATIONS to KATE for successfully passing her VIVA! Well done Dr Kate Lauder!!

Our work on the development of 2,5-dimethylpyrrole antitubercular agents is out in ACS Medicinal Chemistry Letters. Congratulations to Meir, Dorothy, Nicolo' and our collaborators from Sao Paulo, Birkbeck, UCL, Siena and Tel Aviv.

The paper is dedicated to the memory of Prof. Maurizio Botta.

Our work on the design and identification of novel Zika virus inhibitors is out in ChemMedChem. Congratulation to Sharon, Giulio, Kate, Carl and Zak and our collaborators from the universities of Marseille, Leuven and Roma La Sapienza

 Dorothy won the Best Poster Award at the IC3TC 2019 Confernce in Lisbon!

A BBSRC LIDO iCASE Studensthip is availble in the group!

if interested please see details on the project and on how to apply at http://lido-dtp.ac.uk/castagnolo.html or email me at daniele.castagnolo@kcl.ac.uk  

Our last work on the synthesis of 1,2-mercaptoamines is out in Organic Biomolecular Chemistry - congratulations to Kate, Domiziana and Anita for their work and thanks to our collaboratoris Proff Gary Black and Nicholas Turner!

Our work on the chemo-enzymatic synthesis of furans using laccase enzyme and ring-closing metathesis is published in ACS Catalysis. Well done Caterina and Fei!

Our last work on the developemnt of novel antibacetrial agents has been just accepted for publication in Eur. J. Med. Chem. - the link to the paper will be  available soon in the "publications" area. Congratulation to Domiziana, Anita, Mohammad, Meir, Siham, Irene for their excellent work and a huge thanks to PHE (Mark, Charlotte and Melanie) and Prof. Silvestri's Team from University of Rome La Sapienza for the collaboration.

Daniele has been awarded with the Thieme Chemistry Journals Award 2019 - a big incentive for our research and a good start for the New Year.