Publications
81. Insights into E. coli Cyclopropane Fatty Acid Synthase (CFAS) towards Enantioselective Carbene Free Biocatalytic Cyclopropanation.
Iman Omar, Michele Crotti, Chuhan Li, Krisztina Pisak, Blazej Czemerys, Salvatore Ferla, Aster van Noord, Caroline E. Paul, Kersti Karu, Cagakan Ozbalci, Ulrike Eggert, Richard Lloyd, Sarah M. Barry and Daniele Castagnolo, Angew. Chem., Int. Ed. 2024, in press
80. Liposome-siderophore conjugates loaded with moxifloxacin serve as a model for drug delivery against Mycobacterium tuberculosis
Camila Maringolo Ribeiro, Cesar Augusto Roque-Borda, Maria Carolina Franzini, Karyn Fernanda Manieri, Fernanda Manaia Demarqui, Débora Leite Campo, Rachel Temperani Amaral Machado, Isabel Cristiane da Silva, Marcela Tavares Luiz, Leonardo Delello Di Filippo, Patrícia Bento da Silva, Márcia Cristina Oliveira da Rocha, Sônia Nair Báo, Domiziana Masci, Guilherme F.S. Fernandes, Daniele Castagnolo, Marlus Chorilli and Fernando Rogério Pavan, Int. J. Pharm. 2024, in press
79. BacPROTACs targeting Clp protease: a promising strategy for anti-mycobacterial drug discovery
Andressa Francielli Bonjorno, Aline Renata Pavan, Guilherme F. S. Fernandes, Cauê Benito Scarim, Daniele Castagnolo, Jean Leandro Dos Santos, Front. Chem. 2024, 12, Sec. Medicinal and Pharmaceutical Chemistry, in press
78. Development of novel membrane disrupting lipoguanidine compounds sensitizing Gram-negative bacteria to antibiotics
Seong-Heun Kim, Charlotte K. Hind, Guilherme F. S. Fernandes, Jingyue Wu, Dorothy Semenya, Melanie Clifford, Caleb Marsh, Silvia Anselmi, A. James Mason, Kenneth D. Bruce, J. Mark Sutton, Daniele Castagnolo, ACS Med. Chem. Lett. 2024, in press
77. Discovery and rational mutagenesis of methionine sulfoxide reductase (MsrA) biocatalysts to expand the substrate scope of the kinetic resolution of chiral sulfoxides
Silvia Anselmi, Alexandra Carvalho, Angela Serrano-Sanchez, Jose L. Ortega-Roldan, Jill Caswell, Iman Omar, Gustavo Perez-Ortiz, Sarah M. Barry, Thomas S. Moody and Daniele Castagnolo, ACS Catal. 2023, in press
76. Biocatalytic and chemo-enzymatic synthesis of quinolines and 2-quinolones by monoamine oxidase (MAO-N) and horseradish peroxidase (HRP) biocatalysts
Haoyue Xiang, Salvatore Ferla, Carmine Varricchio, Andrea Brancale, Nicola L. Brown, Gary W. Black, Nicholas J. Turner, Daniele Castagnolo, ACS Catal. 2023, in press
75. Oxazolidinones as Versatile Scaffolds in Medicinal Chemistry
Guilherme Felipe Santos Fernandes, Cauê Benito Scarim, Seong-Heun Kim, Jingyue Wu and Daniele Castagnolo, RSC Med. Chem. 2023, in press
74. Pyrimidine derivatives with antitubercular activity
Vladimir Finger, Martin Kufa, Ondrej Soukup, Daniele Castagnolo, Jaroslav Roh, Jan Korabecny, Eur. J. Med. Chem. 2023, 246, 114946
73. Chemoenzymatic Cascades for the Enantioselective Synthesis of β-Hydroxysulfides Bearing a Stereocentre at the C−O or C−S Bond by Ketoreductases
Fei Zhao, Kate Lauder, Siyu Liu, James D. Finnigan, Simon B. R. Charnock, Simon J. Charnock, Daniele Castagnolo, Angew. Chem., Int. Ed. 2022, 61, e202202363
72. Tuberculosis Drug Discovery: Challenges and New Horizons
Guilherme F. S. Fernandes, Andrew M. Thompson, Daniele Castagnolo, William A. Denny, Jean L. Dos Santos, J. Med. Chem. 2022, 65, 7489-7531
71. Tapping into the antitubercular potential of 2,5-dimethylpyrroles: a structure-activity relationship interrogation
Dorothy Semenya, Meir Touitou, Domiziana Masci, Camila Maringolo Ribeiro, Fernando Rogerio Pavan, Guilherme Felipe Dos Santos Fernandes, Beatrice Gianibbi, Fabrizio Manetti, Daniele Castagnolo, Eur. J. Med. Chem. 2022, 237, 114404
70. Structural rigidification of N-aryl-pyrroles into indoles active against intracellular and drug-resistant mycobacteria
Dorothy Semenya, Meir Touitou, Camila Maringolo Ribeiro, Fernando Rogerio Pavan, Luca Pisano, Vinayak Singh, Kelly Chibale, Georg Bano, Anita Toscani, Fabrizio Manetti, Beatrice Gianibbi, Daniele Castagnolo, ACS Med. Chem. Lett. 2022, 13, 63-69
69. Biocatalysis, an Introduction. Exploiting Enzymes as Green Catalysts in the Synthesis of Chemicals and Drugs
Domiziana Masci and Daniele Castagnolo in "Sustainable Organic Synthesis: Tools and Strategies" 2022, Chapter 4, Eds Stefano Protti, Alessandro Palmieri, RSC.
68. Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses
Anita Toscani, Rossana Denaro, Sergio Fernando Castillo Pacheco, Matteo Biolatti, Silvia Anselmi, Valentina Dell’Oste, Daniele Castagnolo, Molecules 2021, 26, 4927
67. Antimicrobial drugs bearing guanidine moieties: a review
Seong-Heun Kim, Dorothy Semenya, Daniele Castagnolo, Eur. J. Med. Chem. 2021, 216, 113293
66. Development of photoactivable phenanthroline-based manganese(I) CO-Releasing Molecules (PhotoCORMs) active against ESKAPE bacteria and bacterial biofilms
Anita Toscani, Charlotte Hind, Melanie Clifford, Seong-Heun Kim, Antonia Gucic, Charlotte Woolley, Naima Saeed, Khondaker Miraz Rahman, J. Mark Sutton and Daniele Castagnolo, Eur. J. Med. Chem. 2021, 213, 113172
65. A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent
Silvia Anselmi, Siyu Liu, Seong-Heun Kim, Sarah M. Barry, Thomas S. Moody and Daniele Castagnolo, Org. Biomol. Chem. 2021, 19, 156-161
64. Propargylamines: recent advances in asymmetric synthesis and use as chemical tools in organic chemistry
Fei Zhao, Seong Heun Kim, Daniele Castagnolo in "Methodologies in Amine Synthesis: Challenges and Applications" 2021, Chapter 4, Eds. Alfredo Ricci, Luca Bernardi, Wiley.
63. Unconventional biocatalytic approaches for the synthesis of chiral sulfoxides
Silvia Anselmi, Nandini Aggarwal, Thomas S. Moody, Daniele Castagnolo, ChemBioChem 2020, 22, 298-307.
62. Biocatalytic and Chemo-Enzymatic Approaches for the Synthesis of Heterocycles
Fei Zhao, Domiziana Masci, Elena Tomarelli, Daniele Castagnolo, Synthesis 2020, 52, 2948-2961.
61. Monoamine Oxidase (MAO-N) Biocatalyzed Synthesis of Indoles from Indolines Prepared via Photocatalytic Cyclization/Arylative Dearomatization
Fei Zhao, Domiziana Masci, Salvatore Ferla, Carmine Varricchio, Andrea Brancale, Serena Colonna, Gary W. Black, Nicholas J. Turner, Daniele Castagnolo, ACS Catal. 2020, 10, 6414-6421.
60. Enantioselective synthesis of α-thiocarboxylic acids via nitrilase biocatalysed dynamic kinetic resolution of α-thionitriles.
Kate Lauder, Silvia Anselmi, James D. Finnigan, Yuyin Qi, Simon J. Charnock and Daniele Castagnolo, Chem. Eur. J. 2020, 26, 10422-10426.
59. Photo-biocatalytic cascades for the synthesis of volatile sulphur compounds and chemical building blocks.
Kate Lauder and Daniele Castagnolo, Synlett 2020, 31, 737-744. Synpact article
58. Improving the potency of N-aryl-2,5-dimethylpyrroles against multidrug-resistant and intracellular mycobacteria.
Meir Touitou, Fabrizio Manetti, Camila Maringolo Ribeiro, Fernando Rogerio Pavan, Nicolò Scalacci, Katarina Zrebna, Neelu Begum, Dorothy Semenya, Antima Gupta, Sanjib Bhakta, Timothy D. McHugh, Hanoch Senderowitz, Melina Kyriazi and Daniele Castagnolo, ACS Med. Chem. Lett. 2020, 11, 638-644.
Special issue dedicated to the memory of Prof. Maurizio Botta
57. Design, synthesis and discovery of novel N,N’-carbazoyl-aryl-urea inhibitors of Zika NS5 methyltransferase and virus replication
Sharon Spizzichino, Giulio Mattedi, Kate Lauder, Coralie Valle, Wahiba Aouadi, Bruno Canard, Etienne Decroly, Suzanne J.F. Kaptein, Johan Neyts, Carl Graham, Zakary Sule, David J. Barlow, Romano Silvestri and Daniele Castagnolo, ChemMedChem 2020, 15, 385-390.
56. A facile and regioselective multicomponent synthesis of chiral aryl-1,2-mercaptoamines in water followed by monoamine oxidase (MAO-N) enzymatic resolution
Kate Lauder, Domiziana Masci, Anita Toscani, Aya Al Mekdad, Gary W. Black, Nicola L. Brown, Nicholas J. Turner, Renzo Luisi and Daniele Castagnolo, Org. Biomol. Chem. 2019, 17, 8982-8986
55. Chemo-Enzymatic Metathesis/Aromatization Cascades for the Synthesis of Furans: Disclosing the Aromatizing Activity of Laccase/TEMPO in Oxygen-Containing Heterocycles
Caterina Risi, Fei Zhao and Daniele Castagnolo, ACS Catal. 2019, 9, 7264-7269
54. Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents.
Venkatesan Jayaprakash, Daniele Castagnolo, Yusuf Ozkay, CRC Press, 2019, 1st Edition
53. Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: Structure-activity relationships and mode of action studies
Domiziana Masci, Charlotte Hind, Mohammad K. Islam, Anita Toscani, Melanie Clifford, Antonio Coluccia, Irene Conforti, Meir Touitou, Siham Memdouh, Xumin Wei, Giuseppe La Regina, Romano Silvestri, J. Mark Sutton and Daniele Castagnolo, Eur J. Med. Chem. 2019, 178, 500-514.
52. Synthesis, Biological Evaluation and Mode of Action Studies of Novel Amidinourea Inhibitors of Hepatitis C Virus (HCV)
Andrea Magri, Omar Mokrane, Kate Lauder, Arvind H. Patel and Daniele Castagnolo, Bioorg. Med. Chem. Lett. 2019, 29, 724-728.
51. Monoamine oxidase (MAO-N) whole cells biocatalyzed aromatization of 1,2,5,6-tetrahydropyridines into pyridines
Anita Toscani, Caterina Risi, Gary W. Black, Nicola L. Brown, Ali Shaaban, Nicholas J. Turner, and Daniele Castagnolo, ACS Catal. 2018, 8, 8781-8787
50. An Iron Catalyzed Reductive Amination of Aldehydes in Isopropyl Alcohol l/Water media as Hydrogen Sources
Elena Petricci, Niccolò Santillo , Daniele Castagnolo, Elena Cini, Maurizio Taddei, Adv. Synth. Catal. 2018, 360, 2560-2565.
49. Photo-biocatalytic one-pot cascades for the enantioselective synthesis of 1,3-mercaptoalkanol volatile sulfur compounds
Kate Lauder, Anita Toscani, Yuyin Qi, Jesmine Lim, Simon J. Charnock, Krupa Korah, and Daniele Castagnolo, Angew. Chem., Int. Ed. 2018, 57, 5803-5807.
48. Synthesis and reactivity of propargylamines in organic chemistry
Kate Lauder, Anita Toscani, Nicolὸ Scalacci, and Daniele Castagnolo, Chem. Rev. 2017, 117, 14091-14200.
47. Synthesis and biological evaluation of amidinourea and triazine congeners as inhibitors of MDA-MB-231 human breast cancer cell proliferation
Rosemary Bass, Sarah Jenkinson, Jennifer Wright,Tora Smulders-Srinivasan, Jamie C. Marshall, Daniele Castagnolo, ChemMedChem 2017, 12, 1-5.
46. Unveiling the biocatalytic aromatizing activity of monoamino oxidases MAO-N and 6-HDNO: development of chemoenzymatic cascades for the synthesis of pyrroles
Nicolo Scalacci, Gary W. Black, Giulio Mattedi, Nicola L. Brown, Nicholas J Turner, Daniele Castagnolo, ACS Catal. 2017, 7, 1295-1300.
45. Synthesis and SAR evaluation of novel thioridazine derivatives active against drug-resistant tuberculosis
Nicolò Scalacci, Alistair K. Brown, Fernando R. Pavan, Camila M. Ribeiro, Fabrizio Manetti, Sanjib Bhakta, Arundhati Maitra, Darren L. Smith, Elena Petricci, Daniele Castagnolo, Eur. J. Med. Chem.2017, 127, 147-158
44.Enyne metathesis reactions in the synthesis of small ring heterocycles
Daniele Castagnolo, in "Targets in Heterocyclic Systems - Volume 20", 2016, Eds. O.A.Attanasi, P.Merino, D.Spinelli, Italian Society of Chemistry.
43. Microwave assisted domino reactions of propargylamines with isothiocyanates: selective synthesis of 2-aminothiazoles and 2-amino-4-methylenethiazolines
Nicolò Scalacci, Chiara Pelloja, Marco Radi, Daniele Castagnolo, Synlett 2016, 27, 1883-1887
42. Design and synthesis of 1-((1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N'-((E)-3,7-dimethyl-octa-2,6-dienyl)-ethane-1,2-diamine (SQ109) pyrrole hybrid derivatives: discovery of potent anti-tubercular agents effective against multi-drug resistant mycobacteria
Sanjib Bhakta, Nicolò Scalacci, Arundhati Maitra, Alistair K. Brown, Saiprasad Dasugari, Dimitrios Evangelopoulos, Timothy D. McHugh, Parisa N. Mortazavi, Alexander Twist, Elena Petricci, Fabrizio Manetti, Daniele Castagnolo, J. Med. Chem. 2016, 59, 2780-2793.
41. A microwave-assisted multicomponent protocol for the synthesis of benzofuran-2-carboxamides
Paolo Vincetti, Anna Brianza, Nicolò Scalacci, Gabriele Costantino, Daniele Castagnolo, Marco Radi, Tetrahedron Letters 2016, 13, 1464–1467
40. A multicomponent pharmacophore fragment-decoration approach to identify selective LRRK2-targeting probes
Sabrina Tassini, Daniele Castagnolo, Nicolò Scalacci, Miroslava Kissova, Jorge I. Armijos-Rivera, Federica Giagnorio, Giovanni Maga, Gabriele Costantino, Emmanuele Crespan, Marco Radi, Med. Chem. Comm. 2016, 7, 484-494
39. Rethinking the old antiviral drug moroxydine: discovery of novel analogues as anti-hepatitis C virus (HCV) agents
Andrea Magri, Roisin Reilly, Nicolo Scalacci, Marco Radi, Michael Hunter, Manon Ripoll, Arvind Patel, Daniele Castagnolo, Bioorg. Med. Chem. Lett. 2015, 25, 5372-5376
38. Discovery of multi-target antivirals acting on both the dengue virus NS5-NS3 interaction and the host Src/Fyn kinases
Paolo Vincetti, Fabiana Caporuscio, Suzanne Keptein, Antimo Gioiello, Valentina Mancino, Youichi Suzuki, Naoki Yamamoto, Emmanuele Crespan, andrea Lossani, Giovanni Maga, Giulio Rastelli, Daniele Castagnolo, Johan Neyts, Pieter Leyssen, Gabriele Costantino, Marco Radi, J. Med. Chem. 2015, 58, 4964-4975.
37. Synthesis of 1,2,3-substituted pyrroles from propargylamines via a one-pot tandem enyne cross metathesis – cyclization reaction
Helene Chachignon, Nicolo' Scalacci, Elena Petricci, Daniele Castagnolo, J. Org. Chem. 2015, 80, 5287-5295.
36. Enantioselective carbolithiation of S-alkenyl-N-aryl thiocarbamates: kinetic and thermodynamic control
Daniele Castagnolo, Leonardo Degennaro, Renzo Luisi, Jonathan Clayden, Org. Biomol. Chem. 2015, 13, 2330-2340
35. The Fight against the Influenza A Virus H1N1: Synthesis, Molecular Modeling, and Biological Evaluation of Benzofurazan Derivatives as Viral RNA Polymerase Inhibitors
Mafalda Pagano, Daniele Castagnolo, Martina Bernardini, Anna Lucia Fallacara, Ilaria Laurenzana, Davide Deodato, Ulrich Kessler, Beatrice Pilger, Lilli Stergiou, Stephan Strunze, Cristina Tintori, Maurizio Botta, ChemMedChem 2014, 9, 129–150
34. Intramolecular arylation of amino acid enolates
Rachel C. Atkinson, Daniel J. Leonard, Julien Maury, Daniele Castagnolo, Nicole Volz, Jonathan Clayden, Chem. Commun. 2013, 49, 9734-9736
33. Carbolithiation of S-Alkenyl-N-aryl Thiocarbamates: Carbanion Arylation in a Connective Route to Tertiary Thiols
Daniele Castagnolo, Daniel J. Foley, Hatice Berber, Renzo Luisi, Jonathan Clayden, Org. Lett. 2013, 15, 2116-2119
32. Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species
Maurizio Sanguinetti, Stefania Sanfilippo, Daniele Castagnolo, Dominique Sanglard, Brunella Posteraro, Giovanni Donzellini, Maurizio Botta, ACS Med. Chem. Lett. 2013, 4, 852–857
31. Discovery and synthesis of novel benzofurazan derivatives as inhibitors of influenza A virus
Ulrich Kessler, Daniele Castagnolo, Mafalda Pagano, Davide Deodato, Martina Bernardini, Beatrice Pilger, Charlene Ranadheera, Maurizio Botta, Bioorg. Med. Chem. Lett. 2013, 23, 5575-5577
30. Studies on the acylation of 4-(2-aminoethylthio)-7-nitrobenzofurazan: the role of bases in promoting the formation of fluorescent S-acyl derivatives through S–N Smiles rearrangement
Daniele Castagnolo, Mafalda Pagano, Martina Bernardini, Maurizio Botta, Tetrahedron Lett. 2012, 53, 5008-5011
29. Chemistry and biological properties of amidinoureas: strategies for the synthesis of unique bioactive hit compounds
Daniele Castagnolo, in “New Strategies in Chemical Synthesis andCatalysis”, 2012, Chapter 5, Ed. Bruno Pignataro, Wiley-VCH
28. Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors
Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, Bonaventura Clotet, José A. Esté, Maurizio Botta, ChemMedChem 2012, 7, 883-896
27. Guanylated Diamines, Triamines, and Polyamines: Chemistry and Biological Properties
Daniele Castagnolo, Silvia Schenone, Maurizio Botta, Chem. Rev. 2011, 111, 5247-5300
26. Src Kinase Inhibitors: An Update on Patented Compounds
Silvia Schenone, Chiara Brullo, Francesca Mosumeci, Marco Radi, Daniele Castagnolo, Curr. Med. Chem. 2011, 18, 5061-5078
25. Iron catalyzed cross coupling between 1-bromoalkynes and Grignard-derived organocuprate reagents
Daniele Castagnolo, Maurizio Botta, Eur. J. Org. Chem. 2010, 17, 3224-3228
24. From Taxuspine X to Structurally Simplified Taxanes with Remarkable P-Glycoprotein Inhibitory Activity
Daniele Castagnolo, Lorenzo Contemori, Giorgio Maccari, Stanislava I. Avramova, Annalisa Neri, Gianpietro Sgaragli, Maurizio Botta, ACS Med. Chem. Lett. 2010, 1, 416-421
23. Synthesis of new linear guanidines and macrocyclic amidinourea derivatives endowed with high antifungal activity against Candida spp. and Aspergillus spp.
Fabrizio Manetti, Daniele Castagnolo, Francesco Raffi, Alessandra T. Zizzari, Suvi Rajamäki, Silvia D’Arezzo, Paolo Visca, Alessandra Cona, Maria Enrica Fracasso, Denise Doria, Brunella Posteraro, Maurizio Sanguinetti, Giovanni Fadda, Maurizio Botta, J. Med. Chem. 2009, 52, 7376-7379
22. Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels–Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles
Marco Radi, Vincenzo Bernardo, Beatrice Bechi, Daniele Castagnolo, Mafalda Pagano, Maurizio Botta, Tetrahedron Lett. 2009, 47, 6572-6575
21. Domino Alkylation-Cyclization Reaction of Propargyl Bromides with Thioureas/Thiopyrimidinones: A New Facile Synthesis of 2-Aminothiazoles and 5H-Thiazolo[3,2-a]pyrimidin-5-ones
Daniele Castagnolo, Mafalda Pagano, Martina Bernardini, Maurizio Botta, Synlett 2009, 2093-2096
20. Synthesis biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: Part 2. Synthesis of rigid pyrazolones.
Daniele Castagnolo, Fabrizio Manetti, Marco Radi, Beatrice Bechi, Mafalda Pagano, Alessandro De Logu, Rita Meleddu, Manuela Saddi, Maurizio Botta, Bioorg. Med. Chem. 2009, 17, 5716-5721
19. Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis
Daniele Castagnolo, Marco Radi, Filippo Dessì, Fabrizio Manetti, Manuela Saddi, Rita Meleddu, Alessandro De Logu, Maurizio Botta, Bioorg. Med. Chem. Lett. 2009, 19, 2203-2205
18. Stereoselective protecting group free synthesis of d,l-gulose ethyl glycoside via multicomponent enyne cross metathesis—hetero Diels–Alder reaction
Daniele Castagnolo, Lorenzo Botta, Maurizio Botta, Carbohydr. Res. 2009, 11, 1285-1288
17. Copper mediated alkyne-enolether cross-metathesis in aqueous medium: direct access to 3-substituted crotonaldehydes
Daniele Castagnolo, Lorenzo Botta, Maurizio Botta, J. Org. Chem. 2009, 74, 3172-3174
16. One Pot Multicomponent Synthesis of 2,3-Dihydropyrans: New Access to furanose-pyranose 1,3-C-C- linked-Disaccharides
Daniele Castagnolo, Lorenzo Botta, Maurizio Botta, Tetrahedron Lett. 2009, 14, 1526-1528
15. Macrocyclization of Di-Boc-guanidino-alkylamines Related to Guazatine Components: Discovery and Synthesis of Innovative Macrocyclic Amidinoureas
Daniele Castagnolo, Francesco Raffi, Gianluca Giorgi, Maurizio Botta, Eur. J. Org. Chem. 2009, 334-337
14. Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis
Daniele Castagnolo, Alessandro De Logu, Marco Radi, Beatrice Bechi, Fabrizio Manetti, Matteo Magnani, Sibilla Supino, Rita Meleddu, Lorenza Chisu, Maurizio Botta, Bioorg. Med. Chem. 2008, 16, 8587-8591
13. Direct Kinetic Formation of Nonanomeric [6.5]-Spiroketals in Aqueous Media
Daniele Castagnolo, Irene Breuer, Petri M. Pihko, J. Org. Chem. 2007, 72, 10081-10087
12. A Versatile Route to C-6 Arylmethyl-Functionalized S-DABO and Related Analogues
Marco Radi, Lorenzo Contemori, Daniele Castagnolo, Raffaella Spinosa, Josè A. Estè, Silvio Massa, Maurizio Botta, Org. Lett. 2007, 9, 3157-3160
11. Synthesis of enantiomerically pure α-[4-(1-substituted)-1,2,3-triazol-4-yl]-benzylacetamides via microwave-assisted click chemistry: towards new potential antimicrobial agents
Daniele Castagnolo, Filippo Dessì, Marco Radi, Maurizio Botta, Tetrahedron: Asymmetry 2007, 11, 1345-1350
10. Pratical syntheses of enantiomerically pure N-acetyl-benzhydrylamines
Daniele Castagnolo, Gianluca Giorgi, Raffaella Spinosa, Federico Corelli, Maurizio Botta, Eur. J. Org. Chem. 2007, 22, 3676-3686
9. Crotylation versus Propargylation: Two Routes for the Synthesis of the C13-C18 Fragment of the Antibiotic Branimycin
Wolfgang Felzmann, Daniele Castagnolo, Daniela Rosenbeiger, Johann Mulzer, J. Org. Chem. 2007, 72, 2182-2186
8. Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J
Maurizio Botta, Silvia Armaroli, Daniele Castagnolo, Gabriele Fontana, Paula Pera, Ezio Bombardelli, Bioorg. Med. Chem. Lett. 2007, 17, 1579-1583.
7. Studies Toward the Synthesis of Byciclic 3,8-Secotaxane Diterpenoid System via Ring Closing Metathesis Strategy
Michela L. Renzulli, Luc Rocheblave, Stanislava I. Avramova, Elena Galletti, Daniele Castagnolo, Federico Corelli, Maurizio Botta, Tetrahedron 2007, 63, 497-509
6. Toward the Synthesis of the Antibiotic Branimycin: Novel Approaches to Highly Substituted cis-Decalin Systems
Johann Mulzer, Daniele Castagnolo, Wolfgang Felzmann, Stefan Marchart, Christian Pilger, Valentine S. Enev, Chem. Eur. J. 2006, 12, 5992-6001
5. Ligand-Based Virtual Screening, Parallel Solution-Phase and Microwave-Assisted Synthesis as Tools to Identify and Synthesize New Inhibitors of Mycobacterium Tuberculosis
Fabrizio Manetti, Matteo Magnani, Daniele Castagnolo, Laura Passalacqua, Maurizio Botta, Federico Corelli, Manuela Saddi, Delia Deidda, Alessandro De Logu, ChemMedChem 2006, 1, 973-989
4. A Pharmacophore Modeling Approach to Design New TaxolMimics: Towards the Synthesis of Potential Anticancer and MDR-Reversing Agents
Michela L. Renzulli, Luc Rocheblave, Stanislava I. Avramova, Elena Galletti, Daniele Castagnolo, Laura Maccari, Stefano Forli, Fabrizio Manetti, Federico Corelli, Maurizio Botta, Arkivoc, 2006, viii, 111-130
3. Antioxidant properties of propargylamine derivatives: assessment of their ability to scavenge peroxynitrite
Stefania Dragoni, Valentina Porcari, Massimiliano Travagli, Daniele Castagnolo, Massimo Valoti, J. Pharm. Pharmacol. 2006, 58, 561-565
2. Microwave-assisted ethylene–alkyne cross-metathesis: synthesis of chiral 2-(N-1-acetyl-1-arylmethyl)-1,3-butadienes
Daniele Castagnolo, Michela L. Renzulli, Elena Galletti, Federico Corelli, Maurizio Botta, Tetrahedron: Asymmetry 2005, 16, 2893-2896
1. Enantioselective synthesis of 1-aryl-2-propenylamines: a new approach to a stereoselective synthesis of the Taxol® side chain
Daniele Castagnolo, Silvia Armaroli, Federico Corelli, Maurizio Botta, Tetrahedron: Asymmetry 2004, 15, 941-949.
