Publications

Book Chapter 书籍章节

Keren Chen, Yi Hong Ong, Clement Yuen, Quan Liu, “Intradermal surface enhanced Raman scattering”, in Imaging in Dermatology, edited by Michael R Hamblin and Pinar Avci, Elsevier (2016) (ISBN: 978-0-12-802838-4), 141-154.

Patent and invention disclosure 专利及发明公开

US Patent Application No. US17/689,834, Mar. 9, 2022, “Diagnostic Device Based On Surface-Enhanced Raman Scattering”, Quan Liu, Clement Yuen.


China Patent Application No. 中国发明专利申请号 2022102238305,Mar. 9, 2022,“基于表面增强拉曼散射的诊断装置”,刘泉和阮健文Quan Liu, Clement Yuen


Singapore Provisional Patent Application No.  10202102374P, March 9, 2021, “A platform for diagnosing malaria infection”, Quan Liu, Clement Yuen.


US Patent No. 9671347, June 6, 2017, "Method Of Diagnosing Malaria Infection In A Patient By Surface Enhanced Resonance Raman Spectroscopy", Quan Liu, Clement Yuen.


US Utility Patent Application No. 13/442,594, Apr. 9, 2012, "Rapid Malaria Diagnosis using Magnetic Nanoparticles", Quan Liu, Clement Yuen.


US Provisional Patent Application, ETPL ref: SRC/P//1670/US, "Zinc Oxide Thin-Film Random Lasers on Silicon Substrate”, S.F. Yu, Clement Yuen, S.P. Lau, H. W. Lee.   

Peer-Reviewed Journal Publications 杂志论文

Yi Zhang, Mohammad O. A. Malik, Jian Kang, Clement Yuen, and Quan Liu, “Sequency encoding single pixel spectroscopy based on Hadamard transform”, Opt. Express 30(17), 30121-30134 (2022).


Wensong Wang, Zesheng Zheng, Chuanshi Yang, Zhongyuan Fang, Shaomeng Wang, Clement Yuen, Kai Tang, Quan Liu, Peter Preiser, and Yuanjin Zheng, "Laser-Induced surface acoustic wave sensing based Malaria parasite detection and analysis",  IEEE Trans. Instrum. Meas., 71, 1-9 (2022).


Clement Yuen, Xiaohong Gao, James Jia Ming Yong, Prem Prakash, Chalapathy Raja Shobana, Perera Adhikarige Taniya Kaushalya, Yuemei Luo, Yanru Bai, Charles Yang Chun, Peter R Preiser, and Quan Liu, "Towards malaria field diagnosis based on surface-enhanced Raman scattering with on-chip sample preparation and near-analyte nanoparticle synthesis", Sensors and Actuators B, 343, 130162 (2021).


Wai Hon Chooi, Quanbin Dong, Jeremy Zhi Yan Low, Clement Yuen, Jiah Shin Chin, Junquan Lin, Liu Quan, and Sing Yian Chew, "Cell membrane-coated electrospun fibers enhance keratinocyte growth through cell-type specific interactions", ACS Applied Bio Materials, 4, 4079 - 4083 (2021).


YanRu Bai, Clement Yuen, and Quan Liu, “A modified least-squares method for quantitative analysis in Raman spectroscopy”, IEEE Journal of Selected Topics in Quantum Electronics, 27(4), 1 - 9 (2021). 


Keren Chen, Clement Yuen, Aniweh Yaw, Peter Preiser and Quan Liu, "Towards ultra-sensitive malaria diagnosis using surface enhanced Raman spectroscopy," Scientific Reports, 6, 20177. (2016).


Clement Yuen, and Quan Liu, "Hollow agarose microneedle with silver coating for intradermal surface-enhanced Raman measurements: a skin-mimicking phantom study", J. Biomed. Opt. 20, 061102 (2015).


Shuo Chen, Xiaoqian Lin, Clement Yuen, Saraswathi Padmanabhan, Roger W. Beuerman, and Quan Liu, "Recovery of Raman spectra with low signal-to-noise ratio using Wiener estimation", Opt. Exp. 22, 12102-12114 (2014).


Clement Yuen, and Quan Liu, "Towards in vivo intradermal surface enhanced Raman scattering (SERS) measurements: silver coated microneedle based SERS probe", J. Biophotonics 7, 683 (2014).


Clement Yuen, and Quan Liu, "Optimization of Fe3O4@Ag nanoshells in magnetic field-enriched surface-enhanced resonance Raman scattering for malaria diagnosis", Analyst 138, 6494 (2013).


Clement Yuen, and Quan Liu, "Magnetic field enriched surface enhanced resonance Raman spectroscopy for early malaria diagnosis", J. Biomed. Opt. 17, 017005 (2012).


Clement Yuen, Wei Zheng, and Zhiwei Huang, "Low-level detection of anti-cancer drug in blood plasma using microwave-treated gold-polystyrene beads surface-enhanced Raman scattering substrates", Biosens. Bioelectron. 26, 580 (2010).


Y. Liu, T. P. Chen, S. F. Yu, Z. X. Li, L. Ding, M. Yang, J. I. Wong, C. Y. Ng, and Clement Yuen, "Si-based light-emitting structure synthesised with low-energy ion implantation at a low dosage", J. Nanosci. Nanotechnol. 10, 595 (2010).


Clement Yuen, Wei Zheng, and Zhiwei Huang, "Optimization of extinction efficiency of gold-coated polystyrene beads substrates improves surface-enhanced Raman scattering effects by post-growth microwave heating treatment", J. Raman Spectrosc. 41, 374 (2009).


Clement Yuen, Wei Zheng, and Zhiwei Huang, "Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with post-growth microwave treatment", J. Biomed. Opt. 13, 064040 (2008).


Clement Yuen, Wei Zheng, and Zhiwei Huang, "Surface-enhanced Raman scattering: principles, nanostructures, fabrications and biomedical applications", J. Innovative Opt. Health Sci. 1, 267 (2008).


Clement Yuen, S. F. Yu, E.S.P. Leong, S.P. Lau, K. Pita, H.Y. Yang, and T.P. Chen, "Room temperature deposition of p-type Arsenic doped ZnO polycrystalline films by laser-assist filtered cathodic vacuum arc technique", J. Appl. Phys. 101, 094905 (2007).


Y. Liu, T. P. Chen, L. Ding, M. Yang, J. I. Wong, C. Y. Ng, S. F. Yu, Z. X. Li, Clement Yuen, F. R. Zhu, M. C. Tan, and S. Fung, "Influence of charge trapping on electroluminescence from Si-nanocrystal light emitting structure", J. Appl. Phys. 101, 104306 (2007).


Clement Yuen, S. F. Yu, S. P. Lau, and George C. K. Chen, "Design and fabrication of ZnO light-emitting devices using filtered cathodic vacuum arc technique", J. Cryst. Growth 287, 204 (2006).


A.P. Abiyasa, S.F. Yu, Clement Yuen and S.P. Lau, "Influence of surface roughness on the lasing performance of highly disordered ZnO films", IEEE Photonics Technology Letters 18, 2380 (2006).


S. P. Lau, H. Y. Yang, S. F. Yu, Clement Yuen, Eunice S. P. Leong, H. D. Li, and H. H. Hng, "Flexible ultraviolet random lasers based on nanoparticles", Small 1, 956 (2005).


H. D. Li, S. F. Yu, A. P. Abiyasa, Clement Yuen, S. P. Lau, H. Y. Yang, and Eunice S. P. Leong, "Strain dependence of lasing mechanisms in ZnO epilayers", Appl. Phys. Lett. 86, 261111 (2005).


C. X. Xu, X. W. Sun, Clement Yuen, B. J. Chen, S. F. Yu, and Z.L. Dong, "Ultraviolet amplified spontaneous emission from self-organized network of zinc oxide nanofibers", Appl. Phys. Lett. 86, 011118 (2005).


Clement Yuen, S. F. Yu, S. P. Lau, Rusli, and T. P. Chen, "Fabrication of n-ZnO:Al/p-SiC(4H) heterojunction light-emitting diodes by filtered cathodic vacuum arc technique", Appl. Phys. Lett. 86, 241111 (2005).


Clement Yuen, S. F. Yu, Eunice S. P. Leong, H. Y. Yang, S. P. Lau and H. H. Hng, "Formation conditions of random laser cavities in annealed ZnO epilayers", IEEE J. Quantum Electron. 41, 970 (2005).


Clement Yuen, S. F. Yu, Eunice S. P. Leong, H. Y. Yang, S. P. Lau, N. S. Chen, and H. H. Hng, "Low-loss and directional output ZnO thin-film ridge waveguide random lasers with MgO capped layer", Appl. Phys. Lett. 86, 031112 (2005).


Clement Yuen, S. F. Yu, X. W. Sun, C. X. Xu, Eunice S. P. Leong, S. P. Lau, and C. K. Chen, "Ultraviolet lasing phenomenon of zinc oxide hexagonal microtubes", Jpn. J. Appl. Phys. 43, 5273 (2004).


S. F. Yu, Clement Yuen, S. P. Lau, W. I. Park, and Gyu-Chul Yi, "Random laser action in ZnO nanorod arrays embedded in ZnO epilayers", Appl. Phys. Lett. 84, 3241 (2004).


S. F. Yu, Clement Yuen, S.P. Lau, and H.W. Lee, "ZnO thin-film random lasers on silicon substrate", Appl. Phys. Lett. 84, 3244 (2004).


S. F. Yu, Clement Yuen, S. P. Lau, and W. J. Fan, "Design and fabrication of zinc oxide thin-film ridge waveguides on silicon substrate with ultraviolet amplified spontaneous emission", IEEE J. Quantum Electron. 40, 406 (2004).


X. W. Sun, S. F. Yu, C. X. Xu, Clement Yuen, B. J. Chen, and S. Li, "Room-temperature ultraviolet lasing from zinc oxide microtubes", Jpn. J. Appl. Phys. 42, L1229 (2003).


Y. G. Wang, Clement Yuen, S. P. Lau, S. F. Yu, and B. K. Tay, "Ultraviolet lasing of ZnO whiskers prepared by catalyst-free thermal evaporation", Chem. Phys. Lett. 377, 329 (2003).


S. F. Yu, Clement Yuen, S. P. Lau, Y. G. Wang, H. W. Lee, and B. K. Tay, "Ultraviolet amplified spontaneous emission from zinc oxide ridge waveguides on silicon substrate", Appl. Phys. Lett. 83, 4288 (2003).



Peer-Reviewed Conference Publications 会议论文

Quan Liu, Clement Yuen, Keren Chen, Jian Ju, Aoli Xiong, and Peter Preiser, “Surface enhanced Raman spectroscopy for malaria diagnosis and intradermal measurements” Plasmonics in Biology and Medicine XV 10509, Photonics West, 27Jan-01Feb, 2018, San Francisco, California, U.S.A.


Keren Chen, Aoli Xiong, Clement Yuen, Peter Preiser, and  Quan Liu, “Investigation of surface enhanced Raman spectroscopy for hemozoin detection in malaria diagnosis” Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, Photonics West, Feb 13-18, 2016, San Francisco, California, U.S.A.


Keren Chen, Aoli Xiong, Clement Yuen, Peter Preiser, and  Quan Liu, “Towards field malaria diagnosis using surface enhanced Raman spectroscopy” Biophotonics: Photonic Solutions for Better Health Care V, Photonics Europe, April 04-07, 2016, Brussels, Belgium.


Clement Yuen, and Quan Liu, “Towards a multi-functional disposable microneedle based probe” Plasmonics in Biology and Medicine XI, Photonics West, Feb 01-06, 2015, San Francisco, California, U.S.A.


Shuo Chen, Xiaoqian Lin, Clement Yuen, Saraswathi Padmanabhan, Roger W. Beuerman, and Quan Liu, "Noise removal of Raman spectra with extremely low signal to noise ratio", Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, Photonics West, Feb 07-12, 2015, San Francisco, California, U.S.A.


Keren Chen, Clement Yuen, and Quan Liu, "Towards early malaria diagnosis using surface enhanced Raman spectroscopy", Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII, Photonics West, Feb 07-12, 2015, San Francisco, California, U.S.A.


Clement Yuen, and Quan Liu "A biocompatible microneedle-based probe for in vivo intradermal surface-enhanced Raman scattering measurements", Plasmonics in Biology and Medicine IX, Feb 1 - 6, 2014, San Francisco, California, U.S.A.


Clement Yuen, and Quan Liu "Investigation of magnetic field enriched surface enhanced resonance Raman scattering performance using Fe3O4@Ag nanoparticles for malaria diagnosis", Colloidal Nanoparticles for Biomedical Applications IX, Feb 1 - 6, 2014, San Francisco, California, U.S.A.


Clement Yuen, and Quan Liu "Ag coated microneedle based surface enhanced Raman scattering probe for intradermal measurements", European Conference on Biomedical Optics 2013, May 12 - 16, 2013, Munich.


Clement Yuen, and Quan Liu "A magnetic-field enriched surface-enhanced resonance Raman spectroscopy strategy towards the early diagnosis of malaria", Plasmonics in Biology and Medicine IX, Jan 22 - 24, 2012, San Francisco, California, U.S.A.


Quan Liu, and Clement Yuen "Effect of magnetic field in malaria diagnosis using magnetic nanoparticles", European Conference on Biomedical Optics 2011, May 24 - 26, 2011, Munich.


Clement Yuen, Quan Liu, "Malaria diagnosis using magnetic nanoparticles", Photonics Global Conference 2010, Dec. 14 - 16, 2010, Singapore.


Clement Yuen, W. Zheng, and Z. Huang, "A specially modified surface-enhanced Raman spectroscopy (SERS) substrate for biomedical applications", Conference on Plasmonics in Biology and Medicine V, Jan. 21 - 22, 2008, San Jose, California, U.S.A. (sponsored by Lee Foundation, Singapore)


Clement Yuen, W. Zheng, and Z. Huang, "Saliva analysis using surface-enhanced Raman spectroscopy technique", Conference on Optics in Health Care and Biomedical Optics III, Nov. 12 - 15, 2008, Beijing, China.


Clement Yuen, W. Zheng, and Z. Huang, "Improving surface-enhanced Raman scattering (SERS) effect using post-growth microwave SERS substrate", Optics Within Life Sciences, 10, Jul. 2 - 4, 2008, Singapore.


C. X. Xu, X. W. Sun, Clement Yuen, S. F. Yu, G. P. Zhu, and Y. P. Cui, "Fabrication and laser action of nanostructual ZnO", 13th International Conference on Advanced Laser Technologies, Sep. 3 - 6, 2005, Tianjin, China.


Clement Yuen, S. F. Yu, S. P. Lau, Rusli, T. P. Chen, H. D. Li, A. P. Abiyasa, N. S. Chen, T. S. Herng, X. H. Ji, S. P. Leong, and H. Y. Yang, "Fabrication of n-ZnO:Al/p-SiC (4H) heterojunction light-emitting diodes by filtered cathodic vacuum arc (FCVA) technique", 3nd International Conference on Materials for Advanced Technologies & IUMRS and 9th International Conference on Advanced Materials, Jun. 3 - 8, 2005, Singapore.


Clement Yuen, S. F. Yu, Eunice S. P. Leong, S. P. Lau, and H.Y. Yang, "Zinc oxide coherent and incoherent random laser from heterolayers on silicon", The 3rd International Workshop on ZnO and Related Materials, Oct. 5 - 8, 2004, Sendai, Japan.


S. F. Yu, Eunice S. P. Leong, S. P. Lau and Clement Yuen, "Formation of Random Laser Action in ZnO Thin Films", 5th International Conference on Thin Film Physics and Application (TFPA2004), May 31 - Jun. 2, 2004, Shanghai, China.


Y. Liu, T. P. Chen, S. F. Yu, Z. X. Li, L. Ding, M. Yang, J. Y. Wong, C. Y. Ng, and Clement Yuen, "Si-based light-emitting structure synthesized with low-energy ion implantation at a very low dosage" The 3rd International Conference on Technological Advances of Thin Films & Surface Coatings, Dec. 11 - 15, 2004, Singapore.


S. P. Lau, H. Y. Yang, S. F. Yu, Clement Yuen, and E. S. P. Leong, "Optically pumped flexible ultraviolet random laser", The 3rd International Workshop on ZnO and Related Materials, Oct. 5 - 8, 2004, Sendai, Japan.


X. W. Sun, S. F. Yu, C. X. Xu, Clement Yuen, and B. J Chen, "UV light-source from a zinc oxide microtube", 8th Asian Symposium on Information Display, Feb. 14 - 17, 2004, Nanjing, China.


S. F. Yu, X. W. Sun, Clement Yuen and S. P. Lau, "Investigation of the ultraviolet lasing characteristics of zinc oxide hexagonal microtubes", IEEE/LEOS International Conference on "Numerical Simulation of Semiconductor Optoelectronic Devices (NUSOD)", Oct. 13 - 16, 2003, Tokyo, Japan.


S. F. Yu, Clement Yuen, Daniel Lau Shu Ping and Tay Beng Kang "Optical pumped ZnO thin film UV resonators on silicon substrate", 2nd International Conference on Materials for Advanced Technologies & IUMRS - International Conference in Asia 2003, Jun. 29 - Jul. 4, 2003, Singapore.