From independent research at IISER (all Kalia lab members' names are shown in bold)
27) Anand, S, Bandyopadhyay, S., Bhoge, P. R., Toraskar, S., Kalia, J*, and Kikkeri, R.* (2025) Activation of the Voltage-Gated Potassium Channel by Amphiphilic Glycopeptides. Chem. Eur. J. 31: e202403943.
26) Bandyopadhyay, S., Mishra, S., and Kalia, J.* (2025) Peptide toxins as tools in ion channel biology. Curr. Opin. Chem. Biol. 84: 102568.
25) Roy, S., Majee, P., Sudhakar, S., Mishra, S., Kalia, J., Pradeepkumar. P. I., and Srivatsan, S. G. (2024) Structural elucidation of HIV-1 G-quadruplexes in a cellular environment and their ligand binding using responsive 19F-labeled nucleoside probes. Chem. Sci. 15: 7982-7991.
24) Singh, Y., Sarkar, D., Duari, S., Shashaank, G., Guru, P. K. I., Hrishikesh, M. V., Singh, D., Bharadwaj, S., and Kalia, J.* (2023) Dissecting the contributions of membrane affinity and bivalency of the spider venom protein DkTx to its sustained mode of TRPV1 activation. J. Biol. Chem. 299: 104903.
23) Khatik, S. Y., Sudhakar, S., Mishra, S., Kalia, J., Pradeepkumar, P. I., and Srivatsan, S. G. (2023) Probing juxtaposed G-quadruplex and hairpin motifs using a responsive nucleoside probe: a unique scaffold for chemotherapy. Chem. Sci. 14: 5627–5637. Press coverage here.
22) Dixit, A. and Kalia, J.* (2023) Protein-Metabolite Interactions: Discovery and Significance. ChemBioChem 24: e202200755.
21) Sarkar, D., Mishra, S., Nisal, R., Majhi, S., Shrivas, R., Singh, Y., Anusree, V. S., and Kalia, J.* (2022) Site-specific fluorescent labeling of the cysteine-rich toxin, DkTx, for TRPV1 ion channel imaging and membrane binding studies. Bioconjugate Chem. 33: 1761–1770.
20) Dixit, A., Jose, G. P., Shanbhag, C., Tagad, N., and Kalia, J.* (2022) Metabolic labeling-based chemoproteomics establishes choline metabolites as protein function modulators. ACS Chem. Biol. 17: 2272–2283.
19) Umar, D., Das, A., Gupta, S., Chattopadhyay, S., Sarkar, D., Mirji, G., Kalia, J., Arimbasseri, G. A., Durdik, J. M., Rath, S., George, A., and Bal, V. (2020) Febrile temperature change modulates CD4 T cell differentiation via a TRPV channel-regulated Notch-dependent pathway. Proc. Natl. Acad. Sci., USA 117: 22357–22366.
18) Sarkar, D., Singh, Y., and Kalia J.* (2018) Protein-lipid interfaces can drive the functions of membrane-embedded protein-protein complexes. ACS Chem. Biol. 13: 2689–2698.
17) Nisal, R., Jose, G. P., Shanbhag, C., and Kalia, J.* (2018) Rapid and reversible hydrazone bioconjugation in cells without the use of extraneous catalysts. Org. Biomol. Chem. 16: 4304–4310.
16) Kalia, J., Milescu, M., Salvatierra, J., Wagner, J., Klint, J. K., King, G. F., Olivera, B. M., and Bosmans, F. (2015) From foe to friend: Using animal toxins to investigate ion channel function. J. Mol. Biol. 427: 158–175.
15) Gilchrist, J., Dutton, S., Diaz-Bustamante, M., McPherson, A., Olivares, N., Kalia J., Escayg, A., and Bosmans, F. (2014) Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents. ACS Chem. Biol. 9: 1204–1212.
From PhD and postdoctoral work
14) Bae, C., Anselmi, C., Kalia, J., Jara-Oseguera, A., Schwieters, C. D., Krepkiy, D., Lee, C. W., Kim, E-H., Kim, J. I., Faraldo-Gómez, J. D., and Swartz, K. J. (2016) Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin. eLife. 5. pii: e11273. doi: 10.7554/eLife.11273.
13) Marshall, C., Agarwal, N., Kalia, J., Grosskopf, V., McGrath, N., Abbott, N. L., Raines, R. T., and Shusta, E. V. (2013) Facile chemical functionalization of proteins through intein-linked yeast display. Bioconjugate Chem. 24: 1634–1644.
12) Kalia, J. and Swartz K. J. (2013) The design principles of paddle motifs in voltage sensors. Nat. Struct. Mol. Biol. 20: 534–535.
11) Kalia, J. and Swartz, K. J. (2013) Exploring structure-function relationships between TRP and Kv channels. Sci. Rep. 3: 1523.
10) Kalia, J. and Swartz K. J. (2013) Common principles of voltage-dependent gating for Hv and Kv channels. Neuron, 77: 214–216.
9) Bae, C., Kalia, J., Song, I., Yu, J. H., Kim, H. H., Swartz, K. J., and Kim, J. I. (2012) High yielding production and refolding of the double-knot toxin, an activator of TRPV1 channels. PLoS One 7: e51516.
8) Kalia, J.. and Swartz, K. J. (2011) Elucidating the mechanism of action of a classical drug: Guanidine compounds as inhibitors of voltage-gated potassium channels. Mol. Pharmacol., 80: 1085–1095.
7) Kalia, J. and Raines, R. T. (2010) Advances in bioconjugation. Current Organic Chemistry. 14: 138–147.
6) Kalia, J. and Raines, R. T. (2009) 1,9-Bis(2-pyridyl)-1,2,8,9-tetrathia-5-oxanone. Molbank. M642.
5) Kalia, J. and Raines, R. T. (2008) Hydrolytic stability of hydrazones and oximes. Angew. Chem. Int. Ed. Engl. 47: 7523–7526.
4) Bertics, P. J., Ozer, B. H., Wiepz, G. J., Guadarrama, A. G., Abbott, N. L., Lowe, A. M., Bai, Y., Shusta E. V., Agrawal, N., Raines, R. T., and Kalia, J. (2007) Liquid crystal-based analytic technology: Enabling a molecular view of cancer. BIOforum Europe 11: 42–45.
3) Kalia, J. and Raines, R. T. (2007) Catalysis of imido-group hydrolysis in a maleimide conjugate. Bioorg. Med. Chem. Lett. 17: 6286–6289.
2) Kalia, J., Abbott, N. L., and Raines, R. T. (2007) General method for site‑specific protein immobilization by Staudinger ligation. Bioconjugate Chem. 18: 1064–1069.
1) Kalia, J. and Raines, R. T. (2006) Reactivity of intein thioesters: Appending a functional group to a protein. ChemBioChem 7: 1375–1383.
2) Bosmans F. and Kalia, J. Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels. U.S. Patent US9771335 (filed July 31, 2015; issued September 26, 2017).
1) Raines, R. T. and Kalia, J. Reagents and methods for appending functional groups to proteins. U.S. Patent US8242058 (filed July 23, 2007; issued August 14, 2012).