Gene expression, chromosome heterogeneity and the fast-X effect in mammals.

Post date: Mar 9, 2015 11:37:35 AM

Your study on the fast-X is just published in Biology Letters. In this work, we propose that the high Dn/Ds of the X-linked protein-coding genes (the so-called Fast-X) could be a consequence of their low expression level. Interestingly, we also found an extensive between autosome variation in both expression level and Dn/Ds (see Figure 1).

Figure 1 Of Nguyen et al. 2015 : Relationship between chromosome-wide dN/dS and median gene expression levels (RPKM) in six species of mammals.

Nguyen L-P, Galtier N, Nabholz B (2015) Gene expression, chromosome heterogeneity and the fast-X effect in mammals. Biology Letters, 11, 20150010. [link, dataset]