Overview

Laboratory of Lipid Metabolism 

Three pathways of eicosanoid synthesis. 
(Modified from Dr. Guodong Zhang’s laboratory website)

Dietary consumption of ω-3 and ω-6 fatty acids changes the overall physiology of animals and humans. One of the pathways to change the overall physiology is the conversion of ω-3 and ω-6 fatty acids into epoxide derivatives via the enzymes in the epoxygenase (EPOX) pathway. The biochemistry of epoxygenases with respect to their complex interactions with ω-3 and ω-6 fatty acids is largely unknown. 

The prime research direction in our laboratory is to elucidate the biochemical function of the enzymes in the EPOX pathway and to study the biological role of the novel  ω-3 and ω-6 fatty acid epoxides. 


IMPORTANT LINKS

  • Our papers focusing on the biochemistry of EPOX enzymes and thromboxane synthase are here. Publications !!
  • We are a cohesive team of 3 graduate students and 3 undergraduates. The free flow of scientific ideas and innovation is strongly encouraged in our team. Please visit our research group page
  • Click here to see the latest happenings in our laboratory. Latest News!! 
ABOUT THE PI

Our PI, Dr. Das obtained her Ph.D at Princeton University with Prof. Michael Hecht and post-doctoral training with Prof. Stephen G. Sligar at the University of Illinois Urbana Champaign. 

Awards

• Scientist Development Award, American Heart Association (2015)

• Lightening Talk Speaker - LIPID MAPS Meeting 2015

• Lightening Talk Speaker - LIPID MAPS Meeting 2014

• NIEHS Travel Award - Winter Eicosanoid Meeting 2014

• Moog Lecture Series, Hauptman-Woodward Medical Research Institute

• ACS Travel Award

• Outstanding researched award for postdoctoral research by NSF-NU-NSEC

• FMC Corporation Graduate Fellowship, Princeton

• Dean's List for Honorific Fellowship, Princeton

• Science and Engineering First Year Princeton Graduate Fellowship

• CSIR-JRF Fellowship, India

Biography

Aditi received her undergraduate degree in chemistry from St. Stephen College, Delhi, followed by masters at Indian Institute of Technology (I.I.T.) Kanpur. She received her Ph.D in Chemistry with Dr. Michael Hecht at Princeton University. She further did her postdoctoral research with Dr. Stephen Sligar at University of Illinois Urbana Champaign (UIUC). In 2012, Aditi started her own research group in the Department of Comparative Biosciences at UIUC. She is also an affiliate faculty in the Department of Biochemistry, Department of Bioengineering and Beckman Institute for Advanced Science and Technology. 


Funding






 
              
         
 
 
 
 
 
 
 
Subpages (1): Outreach
Comments