2025

1.Homma-Takeda S, Fujishiro H, Tanaka I, Yakumaru H, Taguchi H, Ayama K , Oikawa M, Himeno S. Phosphorus and potassium distributions in the kidneys of mice administered with renal tubular invasion heavy metals by micro-PIXE. Eur. Phys. J. Plus, 2025, in press. 

2. Jubayar AM, Khan S, Sadi J, Goni O, Khatun M, Siddique AE, Kabir E, Timi RK, Beauty SA, Rossi KN, Abedin F, Sarder SJ, Islam S, Sarker K, Hossain S, Sumi D, Saud ZA, Barchosly A, Wahed As, Himeno S, Hossain K. Novel evidence of arsenic-related excess adiposity and its implication in the risk of cardiometabolic diseases. Environ. Res., 2025, Vol.15, 121059.

3.Sumitomo K, Nakayama R, Fujishiro H, Sumi D. Arsenite suppresses IL-2‒ and IL-12‒induced cytokine production in natural killer cells. Fundamental Toxicological Sciences, 2025, Vol.12, No.4, 103-108.

4.Fujishiro H, Matsumoto K, Umemoto H, Tsuneyama K, Matsukawa T, Kubota A, Himeno S, Sumi D. Dynamic intra-renal changes in cadmium distribution detected by LA-ICP-MS in mice administered cadmium–metallothionein. 2025, Metallomics, accept. 

5.Nakayama R, Fujishiro H, Sumi D.  Autocrine inhibition of differentiation in HL-60 cells by secreted proteinase 3. BPB Reports, 2025, Vol.8, No.3, 80-85.

 2024

1. Taguchi H, Sumi D, Uemura A, Matsumoto K, Fujishiro H. Cisplatin caused highly delayed cytotoxicity in the immortalized cells derived from S3 segment of mouse kidney proximal tubules. Toxicol Appl Pharmacol. 2025 Jan;494:117171. doi: 10.1016/j.taap.2024.117171. Epub 2024 Nov 24. PMID: 39592085. 

2. Taguchi H, Fujishiro H , Sumi D. Arsenite increases sialic acid levels on the cellular surface through the inhibition of sialidase activity. Biochem Biophys Res Commun. 2024 Dec 20;739:150973. doi: 10.1016/j.bbrc.2024.150973. Epub 2024 Nov 9. PMID: 39541927.

3.Taguchi H,Sumi D, Himeno S,Fujishiro H. Ferroptosis is involved in cisplatin sensitivity of the S3 segment of immortalized proximal tubule cells.Toxicology. 2024 Aug;506:153840. doi: 10.1016/j.tox.2024.153840. Epub 2024 Jun 1. PMID: 38830481.

4. Khatun M, Haque N, Siddique AE, Wahed AS, Islam MS, Khan S, Jubayar AM, Sadi J, Kabir E, Shila TT, Islam Z, Sarker MK, Banna HU, Hossain S,Sumi D, Saud ZA, Barchowsky A, Himeno S, Hossain K. Arsenic Exposure-Related Hypertension in Bangladesh and Reduced Circulating Nitric Oxide Bioavailability. Environ Health Perspect. 2024 Apr;132(4):47003. doi: 10.1289/EHP13018. Epub 2024 Apr 4. PMID: 38573329; PMCID: PMC10993991.

5. Nishito Y,Fujishiro H, Nagamatsu S, Kambe T. Reduced Mn uptake of pleiotropic ZIP8 SNP is caused by its loss of Mn-responsive accumulation on the cell-surface. Biosci Biotechnol Biochem. 2024 Aug 26;88(9):1019-1026. doi: 10.1093/bbb/zbae076. PMID: 38821503.

 2023

1, Sumi D, Nakamura Y, Takeuchi K, Okamoto Y, Fujishiro H. Effects of methylation of arginine residue 83 on the enzymatic activity of human arsenic (+3 oxidation state) methyltransferase. Toxicol. in vitro, 2023; 105707. 

2. Sumi D, Taguchi H, Takeuchi K, Fujishiro H. CHAC1 exacerbates arsenite cytotoxicity by lowering intracellular glutathione levels. J Toxicol Sci. 2023;48(9):487-494. doi: 10.2131/jts.48.487. PMID: 37661365.

3. Khatun M, Siddique AE, Wahed AS, Haque N, Tony SR, Islam J, Alam S, Sarker MK, Kabir I, Hossain S, Sumi D, Saud ZA, Barchowsky A, Himeno S, Hossain K. Association between serum periostin levels and the severity of arsenic-induced skin lesions. PLoS One.2023 Jan 4;18(1):e0279893. doi: 10.1371/journal.pone.0279893. PMID: 36598904; PMCID: PMC9812306.

 2022

1.Tony SR, Haque N, Siddique AE, Khatun M, Rahman M, Islam Z, Islam MS, Islam J, Hossain S, Hoque MA, Saud ZA,Sumi D, Wahed AS, Barchowsky A, Himeno S, Hossain K. Elevated serum periostin levels among arsenic-exposed individuals and their associations with the features of asthma. Chemosphere. 2022 Mar 9;298:134277. doi: 10.1016/j.chemosphere.2022.134277. Epub ahead of print. PMID: 35278445.

2. Himeno, S.,Fujishiro, H.,Sumi, D. Chapter 6: Bismuth. in “Handbook on the Toxicology of Metals, Volume II. Fifth Edition” (Eds. Nordberg, G. and Costa, M.) Elsevier, 2022.

3.Fujishiro, H., Miyamoto, S.,Sumi, D., Kambe, T., Himeno, S. Effects of individual amino acid mutations of zinc transporter ZIP8 on manganese- and cadmium-transporting activity.Biochem. Biophys. Res. Commun. (2022), 616: 6-32. https://doi.org/10.1016/j.bbrc.2022.05.068

4.Fujishiro, H., Sumino, M.,Sumi, D., Umemoto, H., Tsuneyama, K., Matsukawa, T., Yokoyama, K., Himeno, S. Spatial localization of cadmium and metallothionein in the kidneys of mice at the early phase of cadmium accumulation.J Toxicol Sci.2022;47(12):507-517. doi: 10.2131/jts.47.507. PMID: 36450495.

5. Sarker, M. K., Tony, S. R., Siddique, A. E., Haque, N., Islam, M. S., Hossain, F., Islam, Z., Hossain, S., Hoque, M. A., Saud, Z. A.,Sumi, D., Himeno, S., Hossain, K. Gender differences in the risk of metabolic syndrome among chronic arsenic-exposed individuals in Bangladesh.Expo Health14, 595–608 (2022). https://doi.org/10.1007/s12403-021-00437-1

 2021

1. Ogawa ,M., Okamoto, Y., Himeno, S., Suzukawa,K.,Sumi, D. Arsenite suppresses the transcriptional activity of EVI1 through the binding to CCHC-type Zn finger domain.Biochem Biophys Res Commun.2020 Sep 3;529(4):910-915. doi: 10.1016/j.bbrc.2020.07.024. Epub 2020 Jul 29.

2.Sumi,D., Tsuyama, H., Ogawa,T., Ogawa, M., Himeno, S.Arsenitesuppresses IL-2-dependent tumoricidal activities of natural killer cells.Toxicol Appl Pharmacol.2021 Feb 1;412:115353. doi: 10.1016/j.taap.2020.115353. Epub 2020 Dec 8.

3. Rahman, A., Islam, M. S.,Tony, S. R., Siddique, A. E., Mondal, V., Hosen, Z., Islam, Z., Hossain, M. I., Rahman,M.,Anjum,A., Paul, S. K., Hossen, F.,Sarker, M. K., Hossain, S., Salam, K. A., Haque, A.,Hoque, M. A.,Saud, Z. A., Xin, L.,Sumi,D., Himeno,S., Hossain, K. T helper 2-driven immune dysfunction in chronic arsenic-exposed individuals and its link to the featuresof allergic asthma.Toxicol Appl Pharmacol.2021 Apr 9;115532. doi: 10.1016/j.taap.2021.115532.

4. Himeno, S.,Fujishiro, H. Roles of Zinc Transporters That Control the Essentiality and Toxicity of Manganese and Cadmium.Yakugakuzasshi141 (5), 2021. doi: 10.1248/yakushi.20-00243-5. PMID: 33952754.

5.Fujishiro, H., Taguchi, H., Hamamo, S., Sumi,D., Himeno, S. 41. Comparisons of segment-specific toxicity of platinum-based agents and cadmium using S1, S2, and S3 cells derived from mouse kidney proximal tubules.Toxicology in vitro, 75: 105179. 2021 doi:10.1016/j.tiv.2021.105179. PMID: 33905841.

6.藤代瞳、姫野誠一郎　「第6章 攪乱 第1節　腎臓におけるカドミウムとマンガンの輸送とその攪乱」生命金属ダイナミクス: 生体内における金属の挙動と制御　城　宜嗣、津本浩平　監修（エヌ・ティー・エス出版）2021年, pp313-319. 2021.

7.角 大悟，姫野誠一郎 「環境化学物質および医薬品としてのヒ素化合物」生命金属ダイナミクス: 生体内における金属の挙動と制御　城 宜嗣・津本浩平　監修，（エヌ・ティー・エス出版）2021年，pp. 334-340. 2021.

8. Homma-Takeda,S.,Fujishiro,H., Tanaka,I., Yakumaru,H., Ayama,K., Uehara, A., Oikawa, M., Himeno, S., Ishihara, H. Single-Cell Imaging for Studies of Renal Uranium Transport and Intracellular Behavior.Minerals11 (2), 191, 2021 https://doi.org/10.3390/min11020191

9. Sarker, MK., Tony, SR., Siddique, AE., Karim, MR., Haque, N., Islam, Z., Islam MS., Khatun, M., Islam, J., Hossain, S., Alam, Saud Z., Miyataka, H.,Sumi, D., Barchowsky, A., Himeno, S., Hossain, K. Arsenic Secondary Methylation Capacity Is Inversely Associated with Arsenic Exposure-Related Muscle Mass Reduction.Int J Environ Res Public Health.2021 Sep 15;18(18):9730. doi: 10.3390/ijerph18189730. PMID: 34574656; PMCID: PMC8472591.

 2020

1.Fujishiro, H., Yamamoto, H., Otera, N., Oka, N., Jinno, M., Himeno, S. In vitro evaluation of the effects of cadmium on endocytic uptakes of proteins into cultured proximal tubule epithelial cells.Toxics8(2), E24 (2020) PMID: 32244724 PMCID: PMC7356949 DOI: 10.3390/toxics8020024

 2019

1.Sumi, D., Yoshino, Y., Kameda, R., Himeno, S. Chronic exposure to submicromolar arsenite promotes the migration of human esophageal Het1A cells induced by heparin-binding EGF-like growth factor.Arch. Toxicol. 93(12), 3523 - 3534. (2019) [PubMed]

2.Fujishiro, H., Hamao, S., Isawa, M., Himeno, S. Segment-specific and direction-dependent transport of cadmium and manganese in immortalized S1, S2, and S3 cells derived from mouse kidney proximal tubules.J. Toxicol. Sci. 44(9), 611-619. (2019)　[PubMed]

3.Fujishiro, H., Himeno, S. Gene expression profiles of immortalized S1, S2, and S3 cells derived from each segment of mouse kidney proximal tubules.Fund. Toxicol. Sci.6(4), 117-123. (2019) [J-STAGE]

4. Tsuyama, H.,Fujishiro, H., Himeno, S.,Sumi, D.Arsenite suppresses NO production evoked by lipopolysaccharide and poly(I:C) via the suppression of interferon-β expression in RAW264.7 cells.J. Toxicol. Sci.44(2), 83-92. (2019) [PubMed]