Optical Tweezers
The extremely high gradient electric field (produced near the beam waist of a tightly focused laser beam) creates forces sufficient to trap
micron-sized dielectric particles in three dimensions.
The technique enables particles to be picked up and moved at will using a beam of visible light and hence was christened optical tweezers.
Initially applicable to trap only large size objects (large viruses like the tobacco mosaic virus.) This is due to the diffraction limits affecting the
size of an optical beam. The latter allows to trap viruses 25 nm in size.
In contrast, plasmonic trapping takes advantage of local field enhancement in the vicinity of nanometer sized apertures in metal sheets to
overcome the diffraction limit.
Steven Chu, and Nobel Prize in Physics 1997
Claude Cohen-Tannoudji "for development of methods to cool and trap atoms with laser light."
William D. Phillips
Arthur Ashkin, Nobel Prize in Physics 2018
Gérard Mourou "for groundbreaking inventions in the field of laser physics"
Donna Strickland One half to Arthur Ashkin "for the optical tweezers and their application to biological systems",
the other half to G. Mourou and D. Strickland "for their method of generating high-intensity, ultra-short optical pulses."
J. E. Molloy and M. J. Padgett; Lights, action: optical tweezers; Contemporary Physics 43, 241 (2002).
J. Burkhartsmeyer et al, Optical Trapping, Sizing, and Probing Acoustic Modes of a Small Virus; Appl. Sci. 10, 394 (2020)
doi:10.3390/app10010394
Video Optical Tweezer Fundamentals
Metal Optics (see the last 4 slides, in particular)
Objective: High data rates AND high packing densities (nano sized) devices
Why not Electronics? Electrical interconnects become progressively limited by RC-delay (too much capacitance lowers the bandwidth.)
Why not Photonics? Light propagation is fast BUT subjected to diffraction (thus interconnects can not be made too small in size). Photonics
is diffraction- limited.
Alternative Plasmonics
Surface plasmons wavelengths can reach nanoscale at optical frequencies! (SPPs are “x-ray wavelength” with
optical frequencies.)
Plasmonics naturally interfaces with similar size electronic components
Plasmonics interfaces well with similar operating speed photonic networks
(La Rosa) Bio-applications of surface plasmons (See Section 4.5, page 36 )
Non-Linear Optics
Birefringent crystal to generate entangled photons via spontaneous parametric down-conversion.
Application: Implementation of quantum entangles states and quantum teleportation.
(La Rosa) Quantum-entanglement and Quantum-teleportation
Apparatus to produce polarization-entangled photons (see Fig.4)
Single photon interference (see Figures 1 and 2)
Jesse Catalano, "Spontaneous Parametric Down-Conversion and Quantum Entanglement" (2014). University
Honors Theses. Portland State University Paper 474. https://doi.org/10.15760/honors.474
Multiple-entangled photons from a spontaneous parametric down-conversion source
Diffraction Limited Resolution
Conventional Optical Microscopy (also called Far-field Optical Microscopy.)
Illumination spot size can not be made smaller than the wavelength; hence the name diffraction limited resolution.
High Resolution imaging
Eric Betzig Nobel Prize in Chemistry 2014
Stefan W. Hell "for the development of super-resolved fluorescence microscopy."
William E. Moerner
Near-field Scanning Optical Microscopy. (An alternative to far-field optics; overcoming the limitations imposed by diffraction
effects.)
Eric Betzig Photo Activated Localization Microscopy (PALM)
Method for isolation of single molecules at high densities (up to~ 10E5/(micronE2) based on the serial photoactivation and
subsequent bleaching of numerous sparse subsets of photoactivatable fluorescent protein (PA-FP) molecules within a sample.
Stefan W. Hell Far-Field Optical Nanoscopy
It discusses the physical concepts that have pushed fluorescence microscopy to the nanoscale, once the
prerogative of electron and scanning probe microscopes.