Mutation
Inquiry question: How does mutation introduce new alleles into a population?
Powerpoint that we will be referring to in Module 6 IQ1 is given below:
● explain how a range of mutagens operate, including but not limited to:
– electromagnetic radiation sources
– chemicals
– naturally occurring mutagens
Mutagens are chemical compounds or forms of radiation (such as ultraviolet (UV) light or X-rays) that cause irreversible and heritable changes (mutations) in the cellular genetic material, deoxyribonucleic acid (DNA).
Source: https://www.sciencedirect.com/topics/neuroscience/mutagens
In this dot point, we need to be able to explain (cause and effect) how mutagens work (that is, how do they cause the DNA mutations to occur).
ACTIVITIES:
Read through the Module 6 powerpoint on 'Module 6 - IQ1' attached above this textbox.
Watch the videos that have been attached to this section of this Google site.
Read and complete the question on pages 295-301 of the Year 12 Pearson Biology textbook.
Complete page 6 of the Module 6 'Genetic Change Booklet'.
In class time we will perform the experiment "Does sunscreen protect my DNA?" (hard copy worksheet will be given to you in class and electronic copy is attached to this Google site).
● compare the causes, processes and effects of different types of mutation, including but not limited to:
– point mutation
– chromosomal mutation
Chromosomal alterations are mutations that change chromosome structure.
Point mutations change a single nucleotide.
Frameshift mutations are additions or deletions of nucleotides that cause a shift in the reading frame.
In this dot point, we will answer the COMPARE verb (similarities and differences) and look at describing the processes involved in these types of mutations and then comparing them.
ACTIVITIES:
Read through the Module 6 powerpoint on 'Module 6 - IQ1' attached above this textbox.
Complete pages 3-11 of the Module 6 'Genetic Change Booklet'.
Watch the videos that have been attached to this section of this Google site.
Read and complete the question on pages 288-294 of the Year 12 Pearson Biology textbook.
distinguish between somatic mutations and germ-line mutations and their effect on an organism
Germline mutations occur in sperm, eggs, and their progenitor cells and are therefore heritable.
Somatic mutations occur in other cell types and cannot be inherited by offspring. Somatic and germline mutations matter in health and disease.
ACTIVITIES:
Read through the Module 6 powerpoint on 'Module 6 - IQ1' attached above this textbox.
Complete pages 3-11 of the Module 6 'Genetic Change Booklet'.
Watch the videos that have been attached to this section of this Google site.
Read and complete the question on pages 307-310 of the Year 12 Pearson Biology textbook.
assess the significance of ‘coding’ and ‘non-coding’ DNA segments in the process of mutation
The coding regions are known as genes and contain the information necessary for a cell to make proteins.
Non-protein coding regions are not related directly to making proteins, [and] have been referred to as "junk" DNA.
This dot point uses the verb 'assess' - what does an 'assess' verb require you to do?
Assess: make a judgement and give evidence
You will need to answer the dot point as a written response.
ACTIVITIES:
Read through the Module 6 powerpoint on 'Module 6 - IQ1' attached above this textbox.
Complete pages 3-11 of the Module 6 'Genetic Change Booklet'.
Watch the videos that have been attached to this section of this Google site.
Read and complete the question on pages 303-305 of the Year 12 Pearson Biology textbook.
Construct a written response to the dot point:
Assess the significance of ‘coding’ and ‘non-coding’ DNA segments in the process of mutation
investigate the causes of genetic variation relating to the processes of fertilisation, meiosis and mutation
This dot point is asking you to look closely at the processes of:
fertilisation
meiosis
mutation
Then it is asking you to relate these directly to genetic variation.
You have already investigated all of these processes, now you are asked to link these directly to genetic variation - consider, are all of the processes necessary for genetic variation? Are they ALL necessary? Why/why not?
ACTIVITIES:
Read through the Module 6 powerpoint on 'Module 6 - IQ1' attached above this textbox.
Complete pages 14-18 of the Module 6 'Genetic Change Booklet'.
Watch the videos that have been attached to this section of this Google site.
Read and complete the question on pages 306-310 of the Year 12 Pearson Biology textbook.
evaluate the effect of mutation, gene flow and genetic drift on the gene pool of populations
What do the scientific terms mutation, gene flow, genetic drift and gene pool mean?
You will need to define each of these terms.
This dot point uses the verb 'evaluate' - what does an 'evaluate' verb require you to do?
Evaluate: make a judgement against set criteria and give evidence
You will need to answer the dot point as a written response.
ACTIVITIES:
Read through the Module 6 powerpoint on 'Module 6 - IQ1' attached above this textbox.
Complete pages 19-23 of the Module 6 'Genetic Change Booklet'.
Watch the videos that have been attached to this section of this Google site.
Read and complete the question on pages 310-311 of the Year 12 Pearson Biology textbook.
Construct a written response to the dot point:
Evaluate the effect of mutation, gene flow and genetic drift on the gene pool of populations