Research

Our main goal is to understand muscle ribosome biogenesis, in health and in disease, in young and aging, in exercise and disuse. We are particularly interested in uncovering the role of muscle ribosomes during muscle hypertrophy and during muscle atrophy.  

We apply genetic modified mice models to investigate muscle ribosome biogenesis, and a series of interventions that can promote muscle hypertrophy and atrophy. We use several wet-lab techniques routinely, such as Real-Time PCR, Western blotting, Immunohistochemistry, allied with metabolic labelling, methylation and DNA analysis.