Adult Language and Disorders

Definition

Aphasia

An acquired neurogenic language disorder resulting from an injury to the brain—most typically, the left hemisphere. Aphasia involves varying degrees of impairment in four primary areas:

  • Spoken language expression

  • Spoken language comprehension

  • Written expression

  • Reading comprehension


Aphasia is a language disorder that happens when you have brain damage.

A person with aphasia may have trouble understanding, speaking, reading, or writing.

https://www.asha.org/practice-portal/clinical-topics/aphasia/

https://www.asha.org/public/speech/disorders/aphasia/#about


How Does Aphasia Affect the Brain?

Fluent Aphasia

Patient is able to produce connected speech. Sentence structure is relatively intact but lacks meaning Language comprehension relatively intact. Posterior Lesions, short utterances, many paraphasia's, lexical retrieval deficits.

  • Wernicke's Aphasia- repetition of words/phrases poor, characterized by fluent speech that does not make sense

  • Conduction Aphasia- word finding difficulties; difficulty repeating phrases, main impairment is in the inability to repeat words or phrases. Considered a mild form of aphasia and is relatively rare.

  • Anomic Aphasia- repetition of words/phrases good; word finding difficulties; uses generic fillers (e.g., “thing”) or circumlocution. mild form of aphasia in which the individual has difficulty with word-finding, or naming items.

  • Transcortical Sensory Aphasia- repetition of words/phrases good; may repeat questions rather than answering them (“echolalia”). Produce connected, flowing speech. However, that speech is likely to lack meaning due to word errors and invented words.



Types of Aphasia

Non-Fluent Aphasia

Non-fluent Speech production is halting and effortful Grammar is impaired; content words may be preserved Language comprehension relatively intact. Anterior lesions, preserved articulatory functioning, prosody, melody, and grammar.

  • Broca's Aphasia- repetition of words/phrases poor, the person knows what they want to say but is unable to produce the words or sentence.

  • Global Aphasia- severe expressive and receptive language impairment; may be able to communicate using facial expression, intonation, and gestures. Most severe form of aphasia. In global aphasia, all language modalities are affected – speaking, comprehension, reading, and writing.

  • Transcortical Motor Aphasia- strong repetition skills; may have difficulty spontaneously answering questions. The result of a stroke or brain injury that is NEAR Broca’s area. impairment in spoken language.

  • Mixed Transcortical Aphasia- uncommon type of aphasia. Mixed transcortical aphasia has also been called isolation aphasia. It is considered a more severe form of aphasia. It is similar to global aphasia, with the exception of more functional repetition skills.


**The following are considered “exceptional aphasias,” as they do not fit neatly within this or other common classification systems. **

Crossed Aphasia- Occurs when a person demonstrates language impairment after suffering damage to the hemisphere on the dominant side of the body, rather than the alternate side. Thus, a right handed person who develops aphasia following a right hemisphere stroke exhibits crossed aphasia. Crossed aphasia can be classified into 2 basic types; one is the “mirror image type” and the other is the “anomalous type”. The former is similar to typical left brain damage aphasic profiles and the latter is similar to typical left brain damage profiles in addition to being crossed.

Subcortical Aphasia- results from damage to subcortical regions of the brain (e.g., thalamus or basal ganglia), and symptoms can mirror those that arise from cortical lesions.

Primary Progressive Aphasia (PPA)—despite its name—is a type of dementia. It is characterized by gradual loss of language function in the context of relatively well-preserved memory, visual processing, and personality until the advanced stages.

Alexia- Reading comprehension difficulties.

Agraphia- Written expression difficulties.

https://www.asha.org/practice-portal/clinical-topics/aphasia/#collapse_2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309387/pdf/arm-35-949.pdf

https://www.asha.org/siteassets/practice-portal/aphasia/common-classifications-of-aphasia.pdf

**Aphasia symptoms vary in severity of impairment and impact on communication, depending on factors such as the location and extent of damage and the demands of the speaking situation.

**A person with aphasia often experiences both receptive and expressive spoken language difficulties—each to varying degrees. He or she may have similar difficulties in written language (i.e., reading comprehension and written expression). As with spoken language, written language difficulties can vary in degree.

Paraphasias

Verbal/Semantic: word errors that are related to the target semantically

Literal/Phonemic: word errors that relate to the target phonemically

Perseveration: atypical repetition of words, phrases, topics


Anomia

Naming impairment within all aphasia types


https://nyu.app.box.com/s/qtk0mdq5ssr48rqwiccai6o7qnoa3t58/file/856982783907

https://www.asha.org/practice-portal/clinical-topics/aphasia/#collapse_2

Signs and Symptoms

Agrammatism

Relying on content words

Reduction of function words


Reduced Semantic Richness

Use High frequency words

Substitute with "Thing" or "Stuff"

Spoken Language Expression

  • Having difficulty finding words (anomia)

  • Speaking haltingly or with effort

  • Speaking in single words (e.g., names of objects)

  • Speaking in short, fragmented phrases

  • Omitting smaller words like the, of, and was (i.e., telegraphic speech)

  • Making grammatical errors

  • Putting words in the wrong order

  • Substituting sounds or words (e.g., “table” for bed; “wishdasher” for dishwasher)

  • Making up words (e.g., jargon)

  • Fluently stringing together nonsense words and real words, but leaving out or including an insufficient amount of relevant content


Agraphia- Written Expression

  • Having difficulty writing or copying letters, words, and sentences

  • Writing single words only

  • Substituting incorrect letters or words

  • Spelling or writing nonsense syllables or words

  • Writing run-on sentences that don't make sense

  • Writing sentences with incorrect grammar


Spoken Language Comprehension

  • Having difficulty understanding spoken utterances

  • Requiring extra time to understand spoken messages

  • Providing unreliable answers to “yes/no” questions

  • Failing to understand complex grammar (e.g., “The dog was chased by the cat.”)

  • Finding it very hard to follow fast speech (e.g., radio or television news)

  • Misinterpreting subtleties of language (e.g., taking the literal meaning of figurative speech such as “It's raining cats and dogs.”)

  • Lacking awareness of errors


Alexia- Reading Comprehension

  • Having difficulty comprehending written material

  • Having difficulty recognizing some words by sight

  • Having the inability to sound out words

  • Substituting associated words for a word (e.g., “chair” for couch)

  • Having difficulty reading non-content words (e.g., function words such as to, from, the)


Common Causes of Aphasia

  • Stroke

    • Ischemic—caused by a blockage that disrupts blood flow to a region of the brain

    • Hemorrhagic—caused by a ruptured blood vessel that damages surrounding brain tissue

  • Traumatic brain injury

  • Brain tumors

  • Brain surgery

  • Brain infections

  • Progressive neurological diseases (e.g., dementia)

Etiologies


Aphasia is most often caused by stroke. However, any type of brain damage can cause aphasia. This includes brain tumors, traumatic brain injury, and brain disorders that get worse over time.


**Aphasia is caused by damage to the language centers of the brain. In most people, these language centers are located in the left hemisphere,


**Aphasia can also occur as a result of damage to the right hemisphere; this is often referred to as crossed aphasia, to denote that the right hemisphere is language dominant in these individuals.






https://www.asha.org/practice-portal/clinical-topics/aphasia/#collapse_3

https://www.asha.org/public/speech/disorders/aphasia/#signs

Case History



Pre-Diagnosis

  • Medical History

  • Neurological Exam

  • Family History

  • Social History

  • Education

  • Occupation

  • Cultural Background

  • Current Medications


Post-Diagnosis


  • What difficulties are there with functional communication?

  • What is the impact of the diagnosis on the individual and family?

  • What is the impact on social interactions?

  • What is the impact on the individual's job?

  • What is the Quality of life for the individual?










https://nyu.app.box.com/s/qtk0mdq5ssr48rqwiccai6o7qnoa3t58/file/856982783907

https://www.yumpu.com/en/image/facebook/26486767.jpg

Assessment Information


Standardized and non-standardized methods are used to screen:

  • Oral motor functions

  • Speech production skills

  • Comprehension and production of spoken and written language

  • Cognitive aspects of communication

Hearing


Tasks may include:

Formulaic Expressions

  • Conversational/social speech formulae


Recited Speech

  • Pledge of Allegiance

  • Humpty Dumpty

  • Religious Prayers


Automatic speech:

  • Counting

  • Reciting days of the week

  • Reciting months of the year

  • Sentence completions for common phrases

  • Producing greetings

Screening

Screening is conducted in the language(s) used by the person, with sensitivity to cultural and linguistic diversity.


Things to consider which might have an impact on screening:

  • Concurrent motor speech impairment such as dysarthria or apraxia


  • Hearing loss and auditory agnosia

(inability to process sound meaning)


  • Language(s) spoken


  • Concurrent cognitive impairment

(e.g., executive function, memory)


  • Visual acuity deficits, visual agnosia, and visual field cuts


  • Upper extremity hemiparesis

(may affect ability to write)


  • Presence of chronic pain from either preexisting or new conditions


  • Poststroke depression


  • Endurance and fatigue

(testing may need to be broken into shorter sessions)

Screening may result in

  • Recommendation for re-screening

  • Recommendation for comprehensive speech, language, swallowing, or cognitive-communication assessments

  • Referral for other examinations or services

(ASHA, 2021) (Bridges, 2021)

Standardized/ Norm-Referenced Tests

The 'cookie-theft' picture

From the Boston Diagnostic Aphasia Examination -Goodglass & Kaplan, 1983

Boston Naming Test

Visual Confrontation Image example from the Boston Naming Test (BNT)

Tables/Skills typically assesed


ERRORS IN SPOKEN LANGUAGE EXPRESSION

  • Having difficulty finding words (anomia)

  • Speaking haltingly or with effort

  • Speaking in single words (e.g., names of objects)

  • Speaking in short, fragmented phrases

  • Omitting smaller words like the, of, and was (i.e., telegraphic speech)

  • Making grammatical errors

  • Putting words in the wrong order

  • Substituting sounds or words (e.g., “table” for bed; “wishdasher” for dishwasher)

  • Making up words (e.g., jargon)

  • Fluently stringing together nonsense words and real words, but leaving out or including an insufficient amount of relevant content


SPOKEN LANGUAGE COMPREHENSION IMPAIRMENTS

  • Having difficulty understanding spoken utterances

  • Requiring extra time to understand spoken messages

  • Providing unreliable answers to “yes/no” questions

  • Failing to understand complex grammar (e.g., “The dog was chased by the cat.”)

  • Finding it very hard to follow fast speech (e.g., radio or television news)

  • Misinterpreting subtleties of language (e.g., taking the literal meaning of figurative speech such as “It's raining cats and dogs.”)

  • Lacking awareness of errors


ERRORS IN WRITTEN EXPRESSION -AGRAPHIA

  • Having difficulty writing or copying letters, words, and sentences

  • Writing single words only

  • Substituting incorrect letters or words

  • Spelling or writing nonsense syllables or words

  • Writing run-on sentences that don't make sense

  • Writing sentences with incorrect grammar


ERRORS IN READING COMPREHENSION- ALEXIA

  • Having difficulty comprehending written material

  • Having difficulty recognizing some words by sight

  • Having the inability to sound out words

  • Substituting associated words for a word (e.g., “chair” for couch)

  • Having difficulty reading noncontent words (e.g., function words such as to, from, the)


ENVIRONMENTAL AND PERSONAL FACTORS

  • Affects of impairment on the quality of life

  • Social/family support structure

  • Patient goals

STRUCTURAL AND FUNCTIONAL IMPAIRMENTS

  • Flaccidity / Spasticity

  • Co-morbidity

  • Hemiparesis/ Anosognosia/ Neglect


Aphasia (asha.org)




Norm data

STATSTICS

IMPORTANTANT FACTORS

  • The outcome of aphasia varies significantly from person to person

  • The most predictive indicator of of long -term recovery is initial aphasia severity

  • Site of the lesion and size

  • Factors that may negatively affect improvement include poststroke depression and social isolation after onset of aphasia

STASTISTICS

  • 180,000 new cases of aphasia per year in the United States

  • Approximately 1 million people, or 1 in 250 in the United States today, are living with aphasia.

  • Aphasia after stroke is more common for older adults than younger adults

  • Fifteen percent of individuals under the age of 65 experience aphasia after their first ischemic stroke; this percentage increases to 43% for individuals 85 years of age and older

  • Wernicke's aphasia and global aphasia occur more commonly in women

  • Broca's aphasia occurs more commonly in men

Aphasia (asha.org)

''Psychosocial is important!"

Non-Standardized

Language Samples

-Naming

-Constructing Sentences

-Yes/No Questions

-Naturalistic Discourse

-Story Telling (Tell me about your childhood....)

(Bridges, 2021)

Auditory Comprehension

Pointing To An Object.

Ex; Can you point to the object that hits nails?

Yes/No Questions.

Ex; Do you like working with tools?

Multi-step Directions.

Ex; How do you build a treehouse?

Sentence Structuring.

Ex; Can you finish this sentence?

(Bridges, 2021)


Associated Behavioral Systems

-Sensorimotor (fine motor functions, oral motor movements, gross motor functions and auditory functions)

-Cognition (memory, function, attention, language and visusospatial)

-Psychosocial (overall emotional state, family and friends support and everyday living enviroment )


**Narrative Writing in patients with dementia is one of the most common assessment methods for assessing a patients’ writing capabilities. The goal is to have the patient write a sentence, or a description of a picture. These two different methods have been proven to show where patients have the biggest areas of impairment.

**The National Adult Reading Test (NART) is the most commonly used assessment to determine premorbid ability. For the NART, it is an oral reading test that consists of 50 single-words. The words are considered irregular words, such as chord, because they do not follow standard grapheme-phoneme rules. The purpose of using irregular words is to remove the guesswork of creating the correct production because it promotes and forces the patient to tap into previous knowledge.

(Nelson, National Adult Reading Test)

Differential Diagnosis


Aphasia Vs. Dysarthria

Dysathria-The muscles used for speech are too weak to control, this often occurs in slurred or delayed speech.

-Level of pitch varies

-Tremors in speech

with stops or flaps

-Distorted vowels

and incorrect production of consonants

-Hyper/Hypo-nasality

-Usage of

incorrect articulation

-Stress vowels

used inaccurately

-Dysarthria

patients have difficulty understanding sentence structures and words

-Dysarthria

patients have difficulty with grammar

-Dysarthria

patients have difficulty comprehending and using written/oral communication

(ASHA, Dysarthria in Adults 2021)

Aphasia Vs. Apraxia

Apraxia, a deficit in the planning and arrangement of speech, is differentiated by:

-decreased rate of speech

-Even stress placed across syllables

-Additions, distortions and substitutions of phoenemes

Apraxia is not characterized by:

-Mastery of grammatical structure

-Mastery of words and meaning

-Mastery of words needed to express thoughts

-Ability to produce written texts

(ASHA, ACQUIRED APRAXIA 2021)

Assessment Summary

  • Diagnosis

    • Type of Aphasia

    • Auditory Comprehension

    • Verbal Expression

    • Presence of Paraphasias, Perseverations, problems with Naming and word finding (Anomia)

    • Word repetition, phrases, and sentences

    • Agrammatism, or grammatical errors

    • Fluent vs. Nonfluent speech

    • Pragmatic deficiencies or Prosodic features of speech

    • Reading (alexia or dyslexia) and/or writing concerns (agraphia or dysgraphia)

    • Difficulty using or understanding gestures

    • If Bilingual, are impairments present in both languages.

  • Contributing factors

  • Medical diagnosis

  • Pharmacological factors

  • Intelligence and Cognition

  • Age and gender

  • Primary Language

  • Motivation and concerns

  • Cognition concerns

Shipley, K. G., & McAfee, J. G. (2016)

Treatment


Lexical Retrieval

Approach will depend on:

  • Severity of impairment

  • Time of injury relative to time of treament (chronic vs. New onset)

  • Treatment time available

  • Characteristics of the client (e.g., Level of motivation, Employment status, What they do for a living... etc.)

  • Language use and needs (e.g., public speaker or lawyer)

  • NOTE: for severe word - retrieval impairments (e.g., global aphasia) may need a different approach to elicit language.

RESTORE FUNCTION:

  • Tasks that focus on accessing the semantic or phonologic system of word retrieval.

  • engage the cognitive mechanishms underlying word retrieval in a different way: trying to restore function or change function, we want to really exercise the cognitive mechanism

  • Goal is to try to reorganize the word-retrieval process overtime; regain some function or change

VS

COMPENSATORY STRATEGIES:

  • circumvent naming impairment for funtional communication

  • circumlocution

  • gesturing

  • writing

Semantic Treatment

Based on the underlying need to strengthen the semantic system for both (1) comprehension and (2) word retrieval.

(1) Comprehension Treatment

  • Sorting pictures into categories

  • auditory word and written word-picture matching (adding category distractors)

  • y/n question verification about semantic characteristics of target pictures

  • rehearsal of words during task (phonologic component)

  • computerized version developed: with and w/o Clinician asisstance (clients can do on their own time e.g., at home.)

(2) Semantic feature analysis

  • Train points to use matrix of cue words (e.g., function, properties, category, action, etc.)

  • when asked to retrieve cued information, sometimes target word is also retrieved

  • research show generalization of retrieval of trained and untrained items


Space retreival Treatment

Producing meaningful words and giving a space of time to retrieve the target again.

  • Patient produces a small set of relevant target words with systematically increased periods between retrieval. (e.g., 30 secs, 1 min., 2, 4, 8 min.)

  • When an error occurs, step back the time of retrieval

  • When target words improve across sessions, introduce new words.

  • Strengthening connections for certain set of words initially than move into new words

  • For best results- collaborate with other professionals (e.g., PT or OT) or caregivers is crucial

  • The level of treatment intensity is intense.



Cuing Hierarchies: provide less support initially, then progress to more as needed.

TYPES:

  • Semantic Cues

  • Orthographic/phonemic cues

  • Target in a different modality

  • Providing the target and asking for repetition

  • Newly developed computerized programs


Phonologic stage treatment:

Based on phonologic representations being activated with oral reading, picture naming, and repetition.

NOTE: word repetition effectiveness is less than comprehension and cuing strategies.

Make clinical judgements in terms of phonologic information of target word corresponding to the picture/description

  • Client able to describe phonological structure of the word

  • Client correctly produced the initial sound of word and produced 2 syllables (e.g., "Hammer", says "Ha.ma")

NOTE: Efficacy - no consensus of whether semantic or phonological treatment is the most optimal

Reorganization Approach

Spelling knowledge is preserved

  • Spelling may facilitate word retrieval through phonemic self-cuing

  • Retention of print-to-sound conversion ability; train to use as a compensatory strategy

  • Can be taught to type letters into a computer to generate initial phoneme of target words (provide self-cues)

Gesture treatment

  • Using gesturing to facilitate correct word retrival (non-symbolic movement can possibly shape into language reorganization)

  • Lexical and praxis systems interact and may mediate improved word retrieval

  • Strategy: Train gesture in isolation, target word in isolation and gesture and word together.

  • Repeat and practice; gesture should elicit production

  • An effective compensatory strategy (e.g., I need "pen" - gesturing writing may elicit the target word)

PACE: Promoting Aphasic's Communicative Effectiveness) protocal

An Activity Barrier

  • Client has to indicate concepts being converyed on the target picture card

  • Client given a picture

  • suppose to communicate what's in the picture without showing you the picture (describing- Clinician does not see the picture)

  • The goal is for the client to say the target word verbally- but if not describe characteristics or gesture or even write or draw

  • Using various modalities that the client has in their toolbox of functional communication

Bridges, K. (2021)

Auditory comprehension impairment treatment

Schuell's STIMULATION APPROACH: Language system not lost/destroyed (it is uncoordinated/reduced efficiency. Idea is to build on what the client has in their disposal and make that work best)

  • Mapping Therapy: Address asyntactic comprehension impairments (common in Broca's aphasia and effective for nonfluent/mixed aphasia) Patient struggles with syntantic structures (e.g., subject/object) and semantic structures (agent/theme);

          • Target sentence typically read or spoken

          • Have client ID the action and verb

          • Have client ID the person or the agent

          • Have client ID the person or the theme (ID can include pointing to the word, writing it out or verbally stating)

Work to improve the client's abiltiy to map the syntactic and the sematic to increase comprehension of sentences.

  • Pointing Drills: Drill with a field of pictures or objects- have Client hear the word of item then point and repeat.

  • Following direction/commands: One-step to multistep; to add complexity use temporal, locative, conditional phrases, descriptive specifics

  • y/n Questions: Simple: Personal and general knowledge questions VS. Complex: Semantics discriminatory questions (e.g.,"do you cook with a hammer?") .

  • Sentence/phrase completion: "cloze procedure": Verbal demand involving production and lexical retrieval to complete sentence. Use simple common phrase or sentences with predictable answers. Complexity: vary topic, word frequence level, number of words in the sentence.

  • Open-ended questions & retelling: Client must have good verbal production with mild - moderate auditory comprehension impairment to use this treatment. (e.g., read paragraph, describe scenario- use personal relevance or interest, then ask open-ended questions to retell the story or ask client to retell the story/information.

Bridges, K. (2021)

Reading and Writing In Aphasia

CART (Copy and Recall Treatment)

  • Repeated copying and delayed recall of target words.

  • Targets should always be relevant to clients

  • If writing is to compensate for spoken language need to use "conversational writing" (e.g., shorten words or conversational tone- no need for academic writing)

MOR (Multiple Oral Reading)

PURE ALEXIA TREATMENT

  • Top-Down processing of words

  • Uses syntactic and semantic contraints

  • text-level material

  • Brief exposure of a whole word will facilitate who word retreival later.

Bridges, K. (2021)

References

ASHA. (2021).Aphasia. American Speech-Language-Hearing Association. Retrieved October 15, 2021, from https://www.asha.org/practice-portal/clinical-topics/aphasia/#collapse_5


Bridges, K. (2021,October 15). Overview of pragmatics [PowerPoint slides]. Communicative Sciences & Disorders, New York University. https://2nyu.speech.steinhardt.nyu.edu/ap/courses/943/sections/87597407-e7b6-4efb-967a-cefea788daf5/coursework/module/8438ebc8-72a3-4ada-be9d-8eb95d5c0db1/segment/2f47ea67-c084-414a-927a-1444c0631e41


Bridges, K. (2021,October 15). What is Aphasia? [PowerPoint slides]. Communicative Sciences & Disorders, New York University.

https://2nyu.speech.steinhardt.nyu.edu/ap/courses/943/sections/87597407-e7b6-4efb-967a-cefea788daf5/coursework/module/8438ebc8-72a3-4ada-be9d-8eb95d5c0db1/segment/2f47ea67-c084-414a-927a-1444c0631e41


Bridges, K. (2021) Adult Language Disorders. [PowerPoint Slides]. 2NYU. Retrieved on October 14, 2021 from https://2nyu.speech.steinhardt.nyu.edu/ap/courses/943/sections/e9071d35-07d3-49a2-a646-2d1760c32ccb/coursework/courseModule/ed4938c4-0120-4397-86bd-9cfd1965124f


Impedovo, D., Pirlo, G., Vessio, G., & Angelillo, M. T. (2019). A handwriting-based protocol

for assessing neurodegenerative dementia. Cognitive Computation, 11(4). https://doi.org/10.1007/s12559-019-09642-2

Nelson, H. E. (1982). The national adult reading test (NART): Test Manual. Windsor, UK:

NFER-Nelson, 124(3).


Shipley, K. G., & McAfee, J. G. (2016). Assessment in speech-language pathology: A resource manual (6th ed.). Boston, MA: Cengage.


Whitworth, A., Webster, J. & Howard, D. (2014). A Cognitive NeuropsyhologicalApproach to Assessment and Intervention in Aphasia: A clinician's guide. (2nd ed.) New York, NY: Psychology Press.