個人簡介
於2009年在國立中興大學獲得生命科學學士學位,並於2014年在國立陽明大學師從連正章教授取得博士學位。他將於2016年4月在德國波恩的德茲內(DZNE)開始在Stefan Remy的實驗室進行博士後研究,並獲得科技部的博士後出國研究計畫的支持。他的願景是搭建細胞/電路基礎的神經機制與認知動物行為之間的橋樑。結合行為測試和體內記錄技術,他提出要找出海馬神經元單一位置偏好的起源。
學歷
學士:國立中興大學
博士:國立陽明大學 (Lien lab, 2009-2014)
博士後研究員:生命科學學院神經科學研究所
突觸前神經活性對齒狀迴抑制性神經訊息傳導之研究 (博士論文)
Rapid Dynamic Changes of Dendritic Inhibition in the Dentate Gyrus by Presynaptic Activity Patterns (PhD thesis) [PDF]
Hsu YT, Chang YG, Liu YC, Wang KY, Chen HM, Lee DJ, Yang SS, Tsai CH, Lien CC, Chern YJ. Enhanced Na+-K+-2Cl- cotransporter 1 underlies motor dysfunction in Huntington's disease. Mov Disord. 2019 Mar 6. [Epub ahead of print]. [PDF] [PubMed]
Huang YY, Liu YC, Lee CT, Lin YC, Wang ML, Yang YP, Chang KY, Chiou SH. Revisiting the Lamotrigine-Mediated Effect on Hippocampal GABAergic Transmission. Int J Mol Sci 2016 Jul 22; 17 (7). E1191. [PDF][PubMed]
Chen WT, Hsieh YF, Huang YJ, Lin CC, Lin YT, Liu YC, Lien CC, Cheng IH. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca2+ Accumulation. Mol Neurobiol 2014 Nov 15. [Epub ahead of print]. [PubMed]
Liu YC, Cheng JK, Lien CC. Rapid Dynamic Changes of Dendritic Inhibition in the Dentate Gyrus by Presynaptic Activity Patterns. J Neurosci 2014 Jan 22; 34(4): 1344-1357. [PDF] [PubMed]
Lee YC, Alexandra D, Majczenko K, Huang YH, Liu YC, Lien CC, Tsai PC, Ichikawa Y, Goto J, Monin ML, Li JZ, Chung MY, Mundwiller E, Shakkottai V, Liu TT, Tesson C, Lu YC, Brice A, Tsuji S, Burmeister M, Stevanin G, Soong BW. Mutations in KCND3 cause spinocerebellar ataxia type 22. Ann Neurol 2012 Dec; 72 (6): 859-69. [PDF] [Supporting Information] [PubMed]
Chiang PH*, Wu PY*, Kuo TW*, Liu YC, Chan CF, Chien TC, Cheng JK, Huang YY, Chiu CD, Lien CC. GABA is Depolarizing in Hippocampal Dentate Granule Cells of the Adolescent and Adult Rats. J Neurosci 2012 Jan 4; 32 (1): 62-67. *Co-First author [PDF] [PubMed]
Lin YC, Liu YC, Huang YY, Lien CC. High-Density Expression of Ca2+-Permeable ASIC1a Channels in NG2 Glia of Rat Hippocampus. PLoS ONE 2010 Sep 10; 5 (9): e12665-e12672. [PDF] [PubMed]
聯絡資訊
rainnyhunter@gmail.com