LIST OF PUBLICATIONS

Tropone-Enabled Pd-Catalyzed C(sp2)H Functionalization of Phenylalanine: Switchable Access to Indoline and Olefinate. S. S. Nayak A. Patnaik; C. K. Jena and Sharma N. K.* Org. Lett. 2025 (Accepted).

https://doi.org/10.1021/acs.orglett.5c03211

PIDA-mediated synthesis of kynurenine derivatives by oxidative fragmentation of the tryptophan scaffold. C. K. Jena; A. Patnaik; S. S. Nayak; S. Kumari; A. Panda; M. Dixit. and Sharma N. K.* Org. Biomol. Chem.. 2025, 23, 3208-3223.

https://doi.org/10.1039/D5OB00057

Recent Advances in Chalcogenation of α-Amino Acids/Peptides: Synthetic and Mechanistic Aspects. R. Bag; M. Kar; N. K. Sharma,* Eur. J. Org. Chem. 2024.

https://doi.org/10.1002/ejoc.202400513

Synthesis and DNA Cleavage studies of Rationally Designed Metallopeptides from N-Salicyl-AA-Picolamide (SAP) and Cu(II) Ion. Subhashree S. Panda, Supriya Kumar, M. Dixit. and Sharma N. K.* New J. Chem. 2024, 48,19188-19194.

Ag(I)-Mediated Site-Selective C(sp2)-H Chalcogenation of Tryptophan-Peptides with Dichalcogenides at Room Temperature. Bag, R; Kar, M. and Sharma N. K.* J. Org. Chem. 2024.

https://doi.org/10.1021/acs.joc.4c01730

Pd(II)-Catalyzed Conversion Of N-Troponyl-Amino Acid Derivatives Into Cationic Troponyl-Oxazolidines, Jena, C. K. and Sharma N. K.* Er. J. Org. Chem. 2024, 28, e202401002.

https://doi.org/10.1002/ejoc.202401002, 10127-10147

Non-benzenoid N-aryl oxalamide: synthesis of troponyl-oxalamide peptides by Pd(ii)-catalyzed C(sp3)–H functionalization of glycinamides Chinmay K. Jena and Sharma N. K.* Org. Biomol. Chem. 2024, 22, 6822-6832.

Pd-Catalyzed Picolinamide-Directed C(sp2)-H Sulfonylation of Amino Acids/Peptides with Sodium Sulfinates. Bag, R. and Sharma N. K.* J. Org. Chem. 2024, 89, 10127-10147.

tRu(II)-Catalyzed C(sp2)–H Activation Annulation: Synthesis of Fluorescent Benzoisoquinolonyl Acetate/Peptides from N-Arylamides and Ethyne at Room Temperature, Gupta, M.; Panda, A. and Sharma N. K.* J. Org. Chem. 2024, 89, 7485-7495 .

Synthesis of R-GABA Derivatives via Pd(II) Catalyzed Enantioselective C(sp3 )-H Arylation and Virtual Validation with GABAB1 Receptor for Potential leads .; Smitha Mohanlal, S.; Saha, D.; Pandey, S.: Acharya, R. and Sharma N. K.* Chemistry-An Asian Journal. 2024, (Accepted). (http://dx.doi.org/10.1002/asia.202400064.)

Fluorescent 2’-deoxyuridine (dU) Analog: Tropolonyl triazolyl-dU (tt-dU) Exhibits Solvatochromism/HeLa Cell Internalization and Its Triphosphate (tt-dUTP) enzymatically incorporates into DNA .; Meher, S.; Gade, C. R. and Sharma N. K.* Synlett. 2023, (Accepted). (https://www.thiemeconnect.com/products/ejournals/abstract/10.1055/a-2201-3756)

Pd-Catalyzed Picolinamide-Directed Late-Stage Chalcogenation of Tryptophan-Containing Peptides, Bag, R.; and Sharma N. K.* J. Org. Chem. 2023, ASAP (https://pubs.acs.org/doi/10.1021/acs.joc.3c01657)

N-Salicyl-AAn-Picolamide Foldameric Peptides Exhibit Quorum Sensing Inhibition of Pseudomonas aeruginosa (PA14), Panda, S. S.; Kumari, S.; Dixit, M. and Sharma N. K.* ACS Omega. 2023, 8, 30349-30358 (https://doi.org/10.1021/acsomega.3c03404 )

Synthesis of N-Isoindolinonyl Peptides via Pd-Catalyzed C(sp2)-H Olefination/activation and Their Conformational Studies, Gupta, M. K.; Panda, A.; Panda, S. and Sharma N. K.* Org. Biomol. Chem. 2023, 21, 5104-5116. (https://doi.org/10.1039/D3OB00742A)

Azulene tethered N-aryl nucleobases: synthesis, morphology and biochemical evaluations, Meher, S. and Sharma N. K.* New. J. Chem. 2023, 47, 5593-5597. (https://doi.org/10.1039/D2NJ06272K)

New Transient Directing Group: Diethoxyethyl-L-Proline Facilitate ortho-Arylation at Aryl-Amines/-Amino acids via Pd-Catalyzed C(sp2)-H Activation, Panda, S. S. and Sharma N. K.* Org. Biomol. Chem. 2023, 21, 1468-1477. (https://doi.org/10.1039/D2OB02145E)

Pd-Catalyzed site selective C(sp2)-H chalcogenation of amino acids and peptides using picolinamide auxiliary, Bag, R. and Sharma, N. K.* Org. Chem. Front (RSC), 2023, 10, 1252-1262. (https://doi.org/10.1039/D2QO01876D)

Tropolone Conjugated DNA: Fluorescent Thymidine Analogue Exhibit Solvatochromisim, Enzymatic Incorporation into DNA and HeLa Cell-Internalization, Meher, S.; Gade, C. R.; Sharma, N. K* ChemBioChem, 2022, (https://doi.org/10.1002/cbic.202200732 ).

One-pot synthesis of cyclic-aminotropiminium carboxylate derivatives with DNA binding and anticancer properties, Palai, B. B., Patel, S. A., Sharma, N. K.* and Dixit, M.* Commun Chem (Nature Portfolio), 2022, 5, 179. (https://doi.org/10.1038/s42004-022-00798-x).

New Amino acid, Hybrid Peptides and BODIPY Analogs: Synthesis and Evaluation of 2-Aminotroponyl-L-Alanine (ATA) Derivatives, Gupta, M. K. and Sharma N. K,* Org. Biomol. Chem. 2022, 20, 9397-9407.(doi.org/10.1039/D2OB01905A )

Synthesis of Aminotroponyl-/Difluoroboronyl aminotropnyl Deoxyuridine Phosphoramidites, Palai, B. B; Panda, S. S.; Sharma, N. K.* Current Protocols, 2022, 2(12), e609.(doi.org/10.1002/cpz1.609 )

Cu-Catalyzed Synthesis of Alkylaminotroponyl Sulfones as Pseudomonas Aeruginosa Quorum Sensing Inhibitors Targeting lasI/R QS Circuitry, Meher, S.; Kumari, S.; Dixit, M.*; Sharma, N. K.* Chemistry-An Asian Journal, 2022, 17, e202200866 (https://doi.org/10.1002/asia.202200866)

Fluorescent DNA Analog: 2-Aminotroponyl-Pyrrolyl-2’-Deoxyuridinyl DNA Oligo Enhance Fluorescence in DNA-duplex as compared to 2-Aminotroponyl-Ethynyl-2’-Deoxyuridinyl DNA Oligo, Bollu, A.; Panda, S. S.; Sharma, N. K.* Nucleosides Nucleotides Nucleic Acids.2022, Aug 24,1-15, (doi.org/10.1080/15257770.2022.2111442 )

Nonbenzenoid BODIPY Analogues: Synthesis, Structural Organization, Photophysical Studies, and Cell Internalization of Biocompatible N-Alkyl-Aminotroponyl Difluoroboron (Alkyl-ATB) Complexes, Palai, B. B.; Kumari, S.; Dixit, M.; and Sharma, N. K.* ACS Omega, 2022, 7, 27334–27346.(https://doi.org/10.1021/acsomega.2c02379)

Novel Cinnamic Acid Analogues: Synthesis of Aminotroponyl Acrylates by Pd(II)-Catalysed C(sp2)-H Olefination, Jena, C. K.; Sharma, N. K. Chem. Commun. 2022, 58, 8077-8080(https://doi.org/10.1039/D2CC02276A)

4-Aminopyrazolonyl Amino Acid Comprising Tri-Peptides Forms Organogel With Co-Solvent (EtOAc:Hexane), Bollu, A.; Giri, P.; Dalabehera, N. R.; Asmi, A. R.; Sharma, N. K. Frontiers in Chemistry, 2022, 10, 821971(https://doi.org/10.3389/fchem.2022.821971 )

Syntheses and Structural Analyses of Ethylenediprolyl Peptides and Their Metal Complexes with Cu(II) Ion, Gupta, M. K.; Jena, C. K.; Balachandra, C.; Sharma, N. K. J. Org. Chem, 2021, 86, 16327–16336.(https://doi.org/10.1021/acs.joc.1c01676 )

Pd-Catalyzed C(sp2)-H Olefination: Synthesis of N-alkylated Isoindolinone Scaffolds from Arylamide of Amino acid esters, Gupta, M. K.; Jena, C. K.; Sharma, N. K. Org. Biomol. Chem. 2021, 19, 10097-10104.(https://doi.org/10.1039/D1OB01997J)

N-Arylated peptide: troponyl residue influences the structure and conformation of N-troponylated-(di/tri)-peptides, Palai, B. B.; Sharma, N. K.* CrystEngComm, 2021, 23, 131-139 (https://doi.org/10.1039/D0CE01386B)

The 2’-caged-tethered-siRNA Shows Light-Dependent Temporal Controlled RNAi activity for GFP gene into HEK293T cells, Bollu, A., Hassan, M. K, Dixit, M. Sharma, N*. Bioorg. Med. Chem. 2020, (DOI:10.1016/j.bmc.2020.115932)

Instability of Amide Bond With TFA (20%): Synthesis, Conformational Analysis and Mechanistic Insights of Cleavable Amide Bond Comprising β-Troponylhydrazino Acid, N. Dalabehera, N.; Meher, S; Palai, B. B.; Sharma, N. K.* ACS Omega, 2020, 5, 26141–26152.(https://doi.org/10.1021/acsomega.0c03729)

Biased Photo Cleavage of N1-/N6-Nitrobenzyl from 2’-hydroxyethyl-Adenosine and their DNA/RNA Caged-Analogues, Bollu, A. Sharma, N. K*. J. Photochem. Photobiol. Chem-A, 2021, 440, 112864.(DOI:10.1016/j.jphotochem.2020.112864 )

Synthesis and biochemical evaluation of Aminopropanolyl-Thymine tri-Phosphate (ap-TTP), Gade, C. R. and Sharma, N. K*., Nucleosides, Nucleotides, and Nucleic Acid. 2020, 39, 730-743.(DOI:10.1080/15257770.2019.1688831)

BODIPY Analogues: Synthesis and Photophysical studies of difluoro Boron complexes from 2-Aminotropone Scaffolds through N,O-Chelation, Palai, B. B.; Soren, R.; Sharma, N. K.* Org. Biomol. Chem., 2019, 17, 6497-6505.(https://doi.org/10.1039/C9OB00915A)

Syntheses of β3-Aryl-Alaninyl Derivatives by sp3 C-H Activation with Pd(OAc)2 Catalyst/Pivalic Acid in DCE and Their Structural Studies in Solid State, Mohanlal, S. Sharma, N. K.* Chem. Select, 2019, 4, 7058-7066(https://doi.org/10.1002/slct.201901592 )

Cleavable Amide Bond: Mechanistic Insight of Cleavable 4-Aminopyrazolyloxy Acetamide at low pH, Bollu, A. Sharma, N. K.* J. Org. Chem. 2019, 84, 5596–5602.(https://doi.org/10.1021/acs.joc.9b00535 )

Tropolone conjugated DNA: pH Induced Fluorescence Enhancement of Tropolone in DNA Duplex, Bollu, A. Sharma, N. K.*, ChemBioChem 2019, 20, 1-10. (https://doi.org/10.1002/cbic.201800822)