Publications

(23) Discovery of leaderless bacteriocins through genome mining

Alkassab D, Sampang J, Budhwani Z, Buragina J, Lussier L, Acedo JZ. 2024. Can J Chem.  https://cdnsciencepub.com/doi/10.1139/cjc-2023-0209

(22) Characterization of the novel leaderless vacteriocin, Bawcin, from Bacillus wiedmannii

Budhwani Z*, Buragina JT*, Lang J, Acedo JZ. 2023. Int J Mol Sci. 24(23):16965. (*Authors contributed equally)

(21) Unexpected methyllanthionine stereochemistry in the morphogenetic lanthipeptide SapT 

Sarksian R, Hegemann JD, Simon MA, Acedo JZ, van der Donk WA. 2022.  J Am Chem Soc. 144(14): 6373-6382.

(20) Transporter protein-guided genome mining for head-to-tail cyclized bacteriocins

Major D, Flanzbaum L, Lussier L, Davies C, Caldo KMP, Acedo JZ. 2021. Molecules. 26(23): 7218.

(19) Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways

Bobeica SC, Zhu L, Acedo JZ, Tang W, van der Donk WA. 2020. Chem Sci. 11: 12854-12870

(18) Substrate recognition by the class II lanthipeptide synthetase HalM2

Rahman IR, Acedo JZ, Liu XR, Zhu L, Arrington J, Gross ML, van der Donk WA. 2020. ACS Chem Bio. 15(6): 1486-1486.

Introducing the Authors: ACS Chem Bio. 15(7): 1724-1730.

(17) O-Methyltransferase-mediated incorporation of a β-amino acid in lanthipeptides

Acedo JZ, Bothwell I, An L, Trouth A, Frazier C, van der Donk WA. 2019. J Am Chem Soc. 141(32): 16790-16801

(16) Characterization of a dehydratase and methyltransferase in the biosynthesis of a ribosomally‐synthesized and post‐translationally modified peptides in Lachnospiraceae

Huo J, Zhao X, Acedo JZ, Estrada P, Nair S, van der Donk WA. 2019. ChemBioChem. 21(1-2): 190-199. Marked as Very Important Paper.

(15) Arabidopsis CTP:phosphocholine cytidylyltransferase is inactivated by SnRK1, bridging phosphatidylcholine biosynthesis and energy homeostasis

Caldo KMP, Xu Y, Falarz L, Jayawardhane K, Acedo JZ, Chen G. 2019.  J Biol Chem. 294(43): 15862-15874. Recommended in F1000 Prime as being of special significance in its field.

(14) The expanding structural variety among bacteriocins from Gram-positive bacteria

Acedo JZ, Chiorean S, van Belkum MJ, Vederas JC. 2018. FEMS Review. 42(6): 805-828.

(13) Insights into the draft genome sequence of bioactives-producing Bacillus thuringiensis DNG9 isolated from Algerian soil-oil slough

Daas MS*, Rosana ARR*, Acedo JZ, Nateche F, Kebbouche-Gana S, Case RJ, Vederas JC. 2018. Stand Genomic Sci. 13(25): 1-10.

(12) Draft genome sequence of Bacillus paralicheniformis F47, isolated from an Algerian salty lake

Daas MS*, Rosana ARR*, Acedo JZ, Douzane M, Nateche F, Kebbouche-Gana S, Vederas JC. 2018. Genome Announc. 6(13): e00190-18. 

(11) Bacillus amyloliquefaciens isolated from Algerian salty lake as a source of biosurfactants and bioactive lipopeptides

Daas MS*, Acedo JZ*, Rosana ARR*, Reiz B, Zheng J, Orata FD, Nateche F, Case RJ, Kebbouche-Gana S, Vederas JC. 2017. FEMS Microbiol Lett. 365(1): 1-9. (*Authors contributed equally)

(10) Identification and three-dimensional structure elucidation of carnobacteriocin XY, a class IIb bacteriocin produced by Carnobacteria

Acedo JZ, Towle KT, Lohans CT, Miskolzie M, McKay RT, Doerksen TA, Vederas JC, Martin-Visscher LA. 2017. FEBS Lett. 591(10): 1349-1459.

(9) Draft genome sequence of Enterococcus canintestini 49, a potential probiotic that produces multiple bacteriocins

Acedo JZ, Romero CI, McMullen LM, Vederas JC, van Belkum MJ. 2017. Genome Announc. 5(40): e01131-17.

(8) Diacylglycerol acyltransferase 1 is regulated by its N-terminal domain in response to allosteric effectors

Caldo KMP, Acedo JZ, Panigrahi R, Vederas JC, Lemieux MJ, Weselake RJ. 2017. Plant Physiol. 175(2): 667-680.

(7) Draft genome sequences of Bacillus cereus E41 and Bacillus anthracis F34 from Algerian salt lakes

Daas MS*, Rosana ARR*, Acedo JZ, Nateche F, Kebbouche-Gana S, Case RJ, Vederas JC. 2017. Genome Announc. 5(20): e00383-17. 

(6) The antimicrobial lipopeptide tridecaptin A1 selectively binds to Gram-negative lipid II

Cochrane SA, Findlay B, Bakhtiary A, Acedo JZ, Rodriguez-Lopez ER, Mercier P, Vederas JC. 2016. Proc Natl Acad Sci. 113(41): 11561-11566. 

(5) Solution structures of phenol-soluble modulins α1, α3 and β2, virulence factors from Staphylococcus aureus. 

Towle KM, Lohans CT, Miskolzie M, Acedo JZ, van Belkum MJ, Vederas JC. 2016. Biochemistry. 55(34): 4798-4806. 

(4) Nuclear magnetic resonance solution structures of lacticin Q and aureocin A53 reveal a structural motif conserved among leaderless bacteriocins with broad-spectrum activity

Acedo JZ, van Belkum MJ, Lohans CT, Towle KT, Miskolzie M, Vederas JC. 2016. Biochemistry. 55(4): 733-742.

(3) Solution structure of acidocin B, a circular bacteriocin from Lactobacillus acidophilus M46

Acedo JZ, van Belkum MJ, Lohans CT, McKay RT, Miskolzie M, Vederas JC. 2015. Appl Environ Microbiol. 81(8): 2910-2918.

(2) Health-promoting lipids from purslane (Portulaca oleracea L.): isolation, characterization, quantification and in vivo assay of angiogenic activity

Acedo JZ, Reyes CT, Rodriguez EB. 2012. Philipp Agric Scientist. 95(4): 362-369.

(1) Chemical composition of purslane (Portulaca oleracea L.) and anti-inflammatory activity of its lipid components

Acedo JZ, Reyes CT, Rodriguez EB. 2012. Philipp J Crop Sci. 37(2): 13-19.