The Medical College Admission Test (MCAT®) is a standardized, multiple-choice exam designed to assess a prospective medical student's knowledge of natural, behavioral, and social sciences, as well as critical thinking and problem-solving skills. The MCAT covers four main sections: Biological and Biochemical Foundations of Living Systems, Chemical and Physical Foundations of Biological Systems, Psychological, Social, and Biological Foundations of Behavior, and Critical Analysis and Reasoning Skills. The MCAT® consists of 230 questions spanning 7 hours and 5 minutes. Scores range from 472-528 with an average of 500. A minimum score of 511 is considered competitive.
Medical schools require the MCAT® for admission because it provides a comprehensive measure of an applicant's readiness for the rigors of medical education. It evaluates the essential academic skills and knowledge that are foundational for success in medical school and beyond. The MCAT® helps admissions committees compare candidates from diverse educational backgrounds and ensures that all incoming students meet a consistent standard of competency.
What Does A Competitive MCAT Score Look Like?
How Is The MCAT® Configured?
Section
Test-Day Certification
Tutorial (optional)
Chemical and Physical Foundations of Biological Systems
Break (optional)
Critical Analysis and Reasoning Skills
Break (optional)
Biological and Biochemical Foundations of Living Systems
Break (optional)
Psychological, Social, and Biological Foundations of Behavior
Void Question
Total Content Time
Total "Seated" Time*
# of Questions
-
-
59
-
53
-
59
-
59
-
-
-
Time Allotted (Minutes)
4
10
95
10
90
30
95
10
95
3
375
425 (7:08 hours)
Example Questions By Section
The NADH: quinone oxidoreductase (Na⁺-NQR) is a transmembrane protein that catalyzes the reaction between NADH and ubiquinone coupled to the pumping of Na⁺ across the plasma membrane, resulting in a Na⁺ concentration gradient.
The electron transport pathway in Na+-NQR is composed of four flavins (FAD, FMNc, FMNb, and riboflavin) and a [2Fe-2S] center, with electrons flowing in the direction: NADH → FAD → [2Fe-2S] → FMNc → FMNb → riboflavin → ubiquinone. Two electrons are transferred from NADH to FAD in the first step of the cycle, but all subsequent steps are one-electron transfers.
Researchers were interested in observing whether Na⁺ has a thermodynamic effect on electron transport. Working with purified Na⁺-NQR from Vibrio cholerae, the researchers used spectroelectrochemistry to investigate the chemical changes that take place during electron transfer and how these changes are impacted by the presence of various cations. Na⁺-NQR was diluted to a final concentration of 0.75 mM in 0.150 M LiCl, NaCl, KCl, RbCl, or NH₄Cl (each solution also contained redox active mediators) and placed in a glass instrument cell with CaF₂ windows. The cell was equipped with two gold “grids,” which served as the working electrodes. The applied potential was varied from +200 mV to −400 mV in 20 mV increments, and a visible spectrum was recorded at each potential after waiting 40 minutes. A computer was necessary to simulate the data since the individual spectral transitions overlap. Redox transitions were assigned based on the spectroscopic changes that took place at each potential. Some of the results and assignments are presented in Table 1.
Question 1
The reaction between NADH and ubiquinone is exergonic, but the reaction, when catalyzed by NA+-NQR, does not generate much heat in vivo. What factor accounts for this difference?
A. is more exothermic as a result of the lower activation.
B. occurs sequentially in several small steps.
C. maintains a large separation between the reacting centers.
D. is couples to the movement of a charged particle against a concentration gradient.
Question 2
What functional group transformation occurs in the product of the reaction catalyzed by NA⁺-NQR?
A. RC(=O)R → RCH(OH)R
B. ROPO₃²⁻ → ROH + Pi
C. RC(=O)NHR' → RCOOH + R'NH₂
D. RC(=O)OR' → RCOOH + R'OH
Question 3
What is the ratio of cation to enzyme in the spectroelectrochemical experiments described in the passage?
A. 1:2
B. 2:1
C. 20:1
D. 200:1
Answers: Q1: D. Q2: A. Q3: D.
As accustomed as we have become to the idea that scientists “construct” theories and “produce” explanations, and regardless of the controversies among scientists, the fact remains that they only disclose to us a world that came into being without the sciences or other human contributions. Galileo may have conceptualized and formalized the phases of Venus, but the phases themselves had manifestly always existed. Galileo’s fabricated hypothesis simply became the acknowledged fact. By contrast, in conceptualizing technological projects, engineers produce fictions. The technology concerned does not, and by definition could not, exist, since it is in the project phase.
This tautology frees the analysis of technological proposals from the burden of confirmation necessary in the analysis of scientific hypotheses. One might argue, of course, that Diesel did not create the principles he applied in his engine any more than Galileo created the astronomical principles he observed, and some would even contend that the engine was therefore as much beyond the control of Diesel as Venus was beyond the control of Galileo. Even so, few would seriously defend the proposition that the diesel engine had always existed and needed only to be discovered. In reference to technology, Platonism is considered an extreme philosophical stance.
The rejection of Platonism means greater freedom for those who study machinery than for those who study nature. The big issues of reality and plausibility do not bother the former. Engineers may freely create fictions, since the projection of a technological possibility from the present, or from five or fifty years in the future, to a time tₓ is a part of their job. They invent a nonexistent means of transportation, with paper passengers, opportunities yet to be created, hypothetical places to be served (often to be themselves designed from scratch), new component industries, an assumed technological revolution. They are novelists, with one difference: Their project, although initially indistinguishable from a novel, will either remain a possibility in a file or be transformed into an object.
At first, projects and the objects to which they pertain are indistinguishable. The two concepts circulate from office to office in the form of plans, memos, discussions, scale models, and occasional synopses. In this stage of signs, language, and text, people influence the object. But once the project is realized and the object real, it is people, outside their offices, who are influenced by it—a Copernican revolution. The gulf between the world of symbols and the world of things is then apparent. The R-312 is no longer a fiction that carries me away in transports of delight; it is a bus that transports me along the Boulevard Saint-Michel.
Still, the creators of technology do not rigidly differentiate symbol from thing, project from object, the novel that excites speculation from the reality inscribed in the nature of things. For as the R-312 passes progressively from fiction to fact, its engineers repeatedly pass between the speculative and the practical realms. The capacity to be liberated from an exclusive concern from reality and to soar into unrealized potential is the quality that gives technological fiction a beauty that the literary novel, a form inherited from the naturalistic nineteenth century, has difficulty in approaching. Only a fiction that is capable of gaining or losing reality can do justice to engineers, those great unhonored figures of culture and history. A fiction with a variable structure—it is this flexibility to which we must aspire in tracking a technological project.
Question 1
Which of the following phrases best expresses the sense of Platonism that is conveyed in the passage (paragraph 2)?
A. The expression of the human spirit through the realm of ideas
B. The derivation of cause and effect from observable relationships
C. The preexistence of concepts that are the prototypes of real objects
D. The inseparability of physical matter and the particular form it takes
Question 2
The passage distinction between technology and science does NOT consider the:
A. role of imagination in the process of scientific discovery.
B. flexibility of technological concepts in the project stage.
C. possibility that potential objects may never be realized.
D. difference in the work done by engineers and scientists.
Question 3
According to the author's account, the experience of working on an engineering project is LEAST like that of:
A. a chef in imagining the menu for a dinner
B. a reporter in gathering facts for an article
C. a travel agent in creating a vacation package
D. an artist in making sketches for a mural
Question 4
According to social psychologists, people tend to respond to words and symbols as if they were the things to which they refer. What would the passage author be most likely to say about this tendency?
A. It must be repeatedly overcome by engineers as a project progresses towards its physical realization.
B. It accords with the distinction between the hypotheses of scientists and the proposals of engineers.
C. It explains the failure to honor great engineers who have turned projects into objects.
D. It implies an overemphasis on plans and working models in technological projects.
Answers: Q1: C. Q2: A. Q3: B. Q4: A.
The microbiome has been investigated for its possible link to non-hereditary diseases. Crohn’s disease (CD) is a non-hereditary chronic inflammatory condition that may affect any part of the gastrointestinal (GI) tract. Causes for CD have not been defined to date; however, research has shown that the profile of the GI tract microbiome is different in healthy versus CD-affected individuals. Therefore, researchers hypothesized that differences in bacterial distribution and the host immune response to GI tract bacteria might play a role in the establishment and progression of the disease.
GI tract bacteria digest dietary fibers and convert them into butyrate, propionate, and acetate. These three molecules modulate the innate immune system response by attenuating the inflammatory response to GI tract commensal bacteria. Furthermore, butyrate is a major source of energy for colonocytes.
The GI tract microbiome of healthy individuals exhibits a predominance of gram-positive bacteria Firmicutes and Bacteroidetes and a reduced amount of Proteobacteria and Actinobacteria. This is in contrast to the microbiome of individuals with CD who have an increase in the number of the gram-negative Proteobacteria, whereas the number of Firmicutes bacteria is highly reduced. Treatment with 5-aminosalicylic acid reduced Proteobacteria without affecting the number of other bacteria in CD-affected individuals. Bacterial characteristics and variations in microbiome between healthy and CD-affected individuals are summarized in Table 1.
Question 1
From Table 1, which bacteria can use galactose as an energy source?
A. Ruminococcus
B. Faecalibacterium
C. Odoribacter
D. Phascolactobacterium
Question 2
From Table 1, in which metabolic process are GI tract bacteria directly involved?
A. Conversion of PS into short chain fatty acids
B. Absorption of amino acids
C. Fermentation of dietary fibers into peptides
D. Absorption of monosaccharides
Question 3
Based on Table 1, what is the most likely associated with a reduction in gram-positive bacteria?
A. Increase in acetate production
B. Increase in use of acetate
C. Decrease in pH
D. Decrease in PS production
Question 4
Based on the passage, the microbiome of CD-affected individuals will result in which physiological change?
A. Increased polypeptide digestion
B. Slower dietary fiber absorption
C. Increased amount of propionate
D. Decreased immune tolerance
Answers: Q1: C. Q2: A. Q3: C. Q4: D.
Using both structural and ecological perspectives, researchers examined childbearing among African American adolescents in metropolitan areas of the U.S.
The structural perspective focuses on how living in low socioeconomic status (SES) neighborhoods can affect the risk of adolescent childbearing. This perspective is divided into two explanations. Structural explanation 1 posits that the shift of industrial production away from urban centers led to an outmigration of middle-class African American families and a subsequent concentration of poverty in some African American neighborhoods. Structural explanation 2 posits that residential segregation in urban areas concentrates poverty and contributes to neighborhood decline.
The ecological perspective suggests that a neighborhood’s impact on childbearing is mediated by characteristics and changes in families. The ecological perspective includes a potentiator model, which refers to correspondence between risks from the environment and those from the family, as well as a protective model, which describes how more affluent families tend to protect their adolescents from risks in the environment.
Data were obtained from the Panel Study of Income Dynamics and were based on a sample of 940 African American females born between 1953 and 1968. By age 20, 37.7% of these females experienced a premarital birth (6.6% by age 16 and 22.8% by age 18). SES was derived from Census data and measured at age 14.
Results indicated that living in a highly segregated neighborhood was associated with an elevated rate of premarital births, regardless of neighborhood SES. In addition, adolescents who lived in low-SES households, lived with one parent, had multiple siblings, or moved frequently experienced higher rates of a premarital first birth before age 20 as compared to those who did not experience these same conditions.
Question 1
The results of the study support which correlation?
A. A positive correlation between degree of neighborhood segregation and neighborhood SES.
B. A positive correlation between degree of neighborhood segregation and rate of premarital births.
C. A negative correlation between neighborhood SES and neighborhood poverty level.
D. A negative correlation between neighborhood poverty level and rate of premarital births.
Question 2
Suburbanization is most likely to be studied by researchers working with which of the four theoretical perspectives from the passage?
A. Structural explanation 1
B. Structural explanation 2
C. Potentiator model
D. Protective model
Question 3
Which combination of theories from the passage is most likely to share assumptions with the life course approach?
A. Structural explanation 1 and structural explanation 2
B. Structural explanation 1 and potentiator model
C. Structural explanation 2 and protective model
D. Potentiator model and protective model
Question 4
Due to the assertion that the local environment influences adolescents'' norms and values, the ecological perspective is most similar to which sociological theory?
A. Social strain theory
B. Disengagement theory
C. Differential association theory
D. Labeling theory
Answers: Q1: B. Q2: A. Q3: D. Q4: C.