115年國防醫學院公衛研究所及博士班熱烈招生中

PUBLICATION

2025

生成式AI打開研究新格局:實戰經驗分享,提升研究硬實力.源遠護理 19卷3期.中華民國114年11月
Shan-Wen Lui, Feng-Cheng Liu, Jun-Fu Lin, Chia-Jung Hsu, Ting-Yu Hsieh, Yu-Tien Chang. Genetic variation at rs11574891 and rs3125003 in NOTCH1 is associated with therapeutic efficacy of Janus kinase inhibitors in Taiwanese patients with rheumatoid arthritis. International Immunopharmacology. 2025 Nov 21;168(Pt 2):115825. doi: 10.1016/j.intimp.2025.115825
Chen, Hung-Yi, Feng-Cheng Liu, Hsian-Cheng Chen, Tan-Mei Liu, Fu-Chiang Yeh, and Yu-Tien Chang. Novel Variants in Arid1b, Spsb1, and Raet1-as Shape Genetic Susceptibility and Protection in Systemic Lupus Erythematosus and Lupus Nephritis. Journal of Translational Autoimmunity 11 (2025/12/01/ 2025): 100322. https://doi.org/https://doi.org/10.1016/j.jtauto.2025.100322
Ya-Mei Tzeng , Senyeong Kao , Wun-Sin Chen , Shueh-Fen Chen , Shan-Ru Li , Yu-Lung Chiu , Yu-Tien Chang* , Yaw-Wen Chang*. Examining frailty phenotypes of community-dwelling older adults in Taiwan using the falls risk for older people in the community – Taiwan version (Tw-FROP-Com). Aging (Albany NY) (2025). https://doi.org/10.18632/aging.206231
Cheng-Hsun Ho, Chia-Lin Chang, Hsyien-Chia Wen, Yu-Tien Chang, Nai-Chia Chang, and Heng-Ching Lin. Nurse's Perspective: Evaluating Importance and Satisfaction with Hospital Patient Infotainment Terminal. Applied Nursing Research 81 (2025/02/01/ 2025): 151902. https://dx.doi.org/https://doi.org/10.1016/j.apnr.2025.151902

2024

Chia-Chao Wu, Pei-Lin Yang, Li-Ting Kao, Yi-Chun Liu, Cai-Mei Zheng, Pauling Chu, Kuo-Cheng Lu, Chi-Ming Chu, Yu-Tien Chang* (2024). Sleep Duration and Kidney Function - Does Weekend Sleep Matter?. Nature and science of sleep, 16, 85–97. https://doi.org/10.2147/NSS.S427687
Huang, Yen-Sung, Kuo-Cheng Lu, Yu-Tien Chang, Shuk-Man Ka, Cheng-Yi Guo, Hsin-Yi Hsieh, Hsiu-Ming Shih, Huey-Kang Sytwu, and Chia-Chao Wu. Melatonin Alleviates Albumin-Induced Tubular Cell Injury by Activating Clock-Controlled Nuclear Enriched Abundant Transcript 1-Mediated Proliferation. ACS Pharmacology & Translational Science 7, no. 11 (2024/11/08 2024): 3607-17. https://dx.doi.org/10.1021/acsptsci.4c00495.
Yu-Tien Chang, Zhi-Jie Hong, Hsueh-Han Tsai, An-Chieh Feng, Tzu-Ya Huang, Jyh-Cherng Yu, Kuo-Feng Hsu, Chi-Cheng Huang, Wei-Zhi Lin, Chi-Ming Chu, Chia-Ming Liang, Guo-Shiou Liao. Hub Metastatic Gene Signature and Risk Score of Breast Cancer patients with Small Tumor Sizes using WGCNA. Breast Cancer (2024). https://doi.org/10.1007/s12282-024-01627-w
Kao Li-Ting, Yang, Hui-Wen, Chang Yu-Tien, Li I-Hsun, Chen Liang-Hsuan, Hu Ya-Chiao, Chen Yi-Hsien. Physician visits for psoriasis and reduced risk of adverse pregnancy outcomes: A nationwide study in Taiwan. Dermatologica Sinica. 42(2):110-119, Apr-Jun 2024.
Jason C Huang, Ming-Chun Li, I-Chieh Huang, Je-Ming Hu, Wei-Zhi Lin, Yu-Tien Chang*. Gene Co-Expression and Mirna Regulation: A Path to Early Intervention in Colorectal Cancer. Human Gene Therapy. 2024 https://www.liebertpub.com/doi/abs/10.1089/hum.2023.207.

2023

Lai, Yi-Hsuan, Yu-Tien Chang, Yu-Jia Chang, Jo-Ting Tsai, Ming-Hsien Li, and Jang-Chun Lin. 2023. "Predictive Value of the Interaction between CEA and Hemoglobin in Neoadjuvant CCRT Outcomes in Rectal Cancer Patients" Journal of Clinical Medicine 12, no. 24: 7690. https://doi.org/10.3390/jcm12247690
Yu Tien Chang, Yen-Han Lee. Associations Between Drug Use and Mental Health Service Utilization Among US Adults. Int J Ment Health Addiction (2023). https://doi.org/10.1007/s11469-023-01201-z
Je-Ming Hu, Feng-Cheng Liu, Chi-Ming Chu, Yu-Tien Chang*. Health Care Trainees’ and Professionals’ Perceptions of ChatGPT in Improving Medical Knowledge Training: Rapid Survey Study Journal of Medical Internet Research 2023;25:e49385. doi: 10.2196/49385
Ting-Yu Hsieh, Jun-Fu Lin, Feng-Cheng Liu, Hsiang-Cheng Chen, Shan-Wen Lui, Yu-Tien Chang*. Functional implications of rs9373441 with FOXP3+Treg and Tr1 for the clinical effectiveness of csDMARDs in Rheumatoid arthritis .Clinica Chimica Acta. 2023. doi: 10.1016/j.cca.2023.117612
Je-Ming Hu, Pei-Yao Liu, Ying-Chuan Chen, Wei-Zhi Lin, Yu-Ching Chou1, Wen-Chiuan Tsai, Chi-Ming Chu, Chia-Chao Wu, Yu-Tien Chang*. A co-regulatory network of SPIB, AQP8, and GUCA2B related to immune infiltration for early-stage colorectal cancer in silico and in vitro. American Journal of Cancer Research 2023 (Accepted)
Yu-Tien Chang, Zhi-Jie Hong, Jyh-Cherng Yu, Wei-Zhi Lin, Tzu-Ya Huang, Hsueh-Han Tsai, An-Chieh Feng, Kuo-Feng Hsu, Chi-Cheng Huang, Chi-Ming Chu, Chia-Ming Liang, Guo-Shiou Liao, Advancing Breast Cancer Subtyping: Optimizing Immunohistochemical Staining Classification with Insights from Real-World Taiwanese Data. American Journal of Cancer Research 2023 (Accepted)
Wei‑Hung Chan, Ching‑Huang Lai, Shu‑Jia Huang, Chung‑Chi Huang, Chung‑Yu Lai,Yi‑Chun Liu, Shiang‑Huei Jiang, Shan‑Ru Li,Ya‑Mei Tzeng, Senyeong Kao,Yu‑Tien Chang, Chia‑Chao Wu, Chao‑Yin Kuo, Kuang‑Chen Hung &Yu‑Lung Chiu, Verifying the accuracy of self-reported smoking behavior in female volunteer soldiers. Sci Rep. 2023;13(1):3438.doi: 10.1038/s41598-023-29699-2.

2022

Wu Y-S, Wang W-Y, Chan T-C, Chiu Y-L, Lin H-C, Chang Y-T, Wu H-Y, Liu T-C, Chuang Y-C, Wu J. Effect of the Nintendo Ring Fit Adventure Exergame on Running Completion Time and Psychological Factors Among University Students Engaging in Distance Learning During the COVID-19 Pandemic: Randomized Controlled Trial. JMIR serious games. 2022;10(1):e35040.
Lin W-Z, Liu Y-C, Lee M-C, Tang C-T, Wu G-J, Chang Y-T, Chu C-M, Shiau C-Y. From GWAS to drug screening: repurposing antipsychotics for glioblastoma. Journal of translational medicine. 2022;20(1):1-13. (Co-corresponding author)
Lin H. C., Shui H. A., Huang K. Y., Lin W. Z., Chang H. Y., Lee H. J., Lin Y. C., Huang Y. S., Chen G. R., Yang Y. T., Liu H. L., Wu Y. S., Cheng C. S., Ko C. L., Chang Y. T., Lee J. C., Lin C. S., Wang C. H., Chu C. M. Innovative Hybrid-Alignment Annotation Method for Bioinformatics Identification and Functional Verification of a Novel Nitric Oxide Synthase in Trichomonas vaginalis. Biology (Basel). 2022;11(8):1210.
Ko C-L, Lin W-Z, Lee M-T, Chang Y-T, Lin H-C, Wu Y-S, Lin J-F, Pan K-T, Chang Y-C, Lee K-H. Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population. Journal of Translational Medicine. 2022;20(1):1-15.
Cheng C-S, Huang Y-J, Sun C-A, An C, Chang Y-T, Chu C-M, Chang C-W. Gender-Specific Determinants of eHealth Literacy: Results from an Adolescent Internet Behavior Survey in Taiwan. International Journal of Environmental Research and Public Health. 2022;19(2):664. (Co-corresponding author)
Chang Y-T, Tsai W-C, Lin W-Z, Wu C-C, Yu J-C, Tseng VS, Liao G-S, Hu J-M, Hsu H-M, Chang Y-J. A novel IGLC2 gene linked with prognosis of triple-negative breast cancer. Frontiers in oncology. 2022;11:5761. (First author)
Chang Y-C, Lee D-J, Wei C-LH, Pa C-H, Chen C-C, Chen H-C, Chang Y-T, Wang H-E, Chu P, Lu Kc. SARS-CoV-2 versus other minor viral infection on kidney injury in asymptomatic and mildly symptomatic patients. Virulence. 2022;13(1):1349-57.

2021

Yin J. H., Peng G. S., Chen K. H., Chu C. M., Chien W. C., Kao L. T., Wu C. C., Yang C. W., Tsai W. C., Lin W. Z., Wu Y. S., Lin H. C., Chang Y. T. Long-Term Use of Statins Lowering the Risk of Rehospitalization Caused by Ischemic Stroke Among Middle-Aged Hyperlipidemic Patients: A Population-Based Study. Front Pharmacol. 2021;12:741094. (Corresponding author)
Wu C-C, Wang H-E, Liu Y-C, Zheng C-M, Chu P, Lu K-C, Chu C-M, Chang Y-T. Sleeping, Smoking, and Kidney Diseases: Evidence From the NHANES 2017–2018. Frontiers in Medicine. 2021:1671. (Corresponding author)
Tsai W-H, Wu Y-S, Cheng C-S, Kuo M-H, Chang Y-T, Hu F-K, Sun C-A, Chang C-W, Chan T-C, Chen C-W. A technology acceptance model for deploying masks to combat the COVID-19 pandemic in Taiwan (my health bank): web-based cross-sectional survey study. Journal of Medical Internet Research. 2021;23(4):e27069.
Liu Y-C, Yen L-C, Liaw F-Y, Lin M-H, Chiang S-H, Lin F-G, Lai C-H, Kao S, Chang Y-T, Wu C-C. Gender Differences in the Extended Theory of Planned Behaviour on Smoking Cessation Intention in Young Soldiers. International Journal of Environmental Research and Public Health. 2021;18(15):7834.
Li Y. K., Hsu H. M., Lin M. C., Chang C. W., Chu C. M., Chang Y. J., Yu J. C., Chen C. T., Jian C. E., Sun C. A., Chen K. H., Kuo M. H., Cheng C. S., Chang Y. T., Wu Y. S., Wu H. Y., Yang Y. T., Lin C., Lin H. C., Hu J. M., Chang Y. T. Genetic co-expression networks contribute to creating predictive model and exploring novel biomarkers for the prognosis of breast cancer. Sci Rep. 2021;11(1):7268. (Corresponding author)
Huang Y-S, Lo C-H, Tsai P-H, Hou Y-C, Chang Y-T, Guo C-Y, Hsieh H-Y, Lu K-C, Shih H-M, Wu C-C. Downregulation of AANAT by c-Fos in tubular epithelial cells with membranous nephropathy. Biochemical and Biophysical Research Communications. 2021;584:32-8.

Before 2021

Hsiao P. J., Chiu C. C., Lin K. H., Hu F. K., Tsai P. J., Wu C. T., Pang Y. K., Lin Y., Kuo M. H., Chen K. H., Wu Y. S., Wu H. Y., Chang Y. T., Chang Y. T., Cheng C. S., Chuu C. P., Lin F. H., Chang C. W., Li Y. K., Chan J. S., Chu C. M. Usability of Wearable Devices With a Novel Cardiac Force Index for Estimating the Dynamic Cardiac Function: Observational Study. JMIR Mhealth Uhealth. 2020;8(7):e15331.
Hsu H-M, Chu C-M, Chang Y-J, Yu J-C, Chen C-T, Jian C-E, Lee C-Y, Chiang Y-T, Chang C-W, Chang Y-T. Six novel immunoglobulin genes as biomarkers for better prognosis in triple-negative breast cancer by gene co-expression network analysis. Scientific reports. 2019;9(1):1-12.(Corresponding author)
PoJen Hsiao, Chih-Chien Chiu, Ke-Hsin Lin, Fu-Kang Hu, Pei-Jan Tsai, Chun-Ting Wu, Yuan-Kai Pang, Yu Lin, Ming-Hao Kuo, Kang-Hua Chen, Yi-Syuan Wu, Hao-Yi Wu, Ya-Ting Chang, Yu-Tien Chang, Chia-Shiang Cheng, Chih-Pin Chuu, Fu-Huang Lin, Chi-Wen Chang, Yuan-Kuei Li Sr, Jenq-Shyong Chan, Chi-Ming Chu (2020) Usability of Wearable Devices With a Novel Cardiac Force Index for Estimating the Dynamic Cardiac Function: Observational Study. Journal of Medical Internet Research. JMIR Mhealth Uhealth. 2020;8(7):e15331.
Yeh TC, Wang SC, Chang YT, Yeh CB. Predictors of Nicotine Dependence in Adolescents: Symptoms of Bipolar Disorder and Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology. 2017;27(4):366-73.
Shangkuan W-C, Lin H-C, Chang Y-T, Jian C-E, Fan H-C, Chen K-H, Liu Y-F, Hsu H-M, Chou H-L, Yao C-T. Risk analysis of colorectal cancer incidence by gene expression analysis. PeerJ. 2017;5:e3003.
Lu Y-L, Chien W-C, Lin F-H, Chiu Y-L, Pai L, Chang Y-T, Villarreal DS, Pan C-H, Chang S-C, Lin K-H. Long-term trends in child and youth injury mortality in Taiwan, 1989-2007. Journal of Medical Sciences. 2015;35(4):147.
Huang CS, Terng HJ, Chang CW, Chou YC, Chang YT, Chen CY, Lee WJ, Yao CT, Chou HL, Lee CY. A gene expression profile of peripheral blood in colorectal cancer. J Microb Biochem Technol. 2014;6(2):102-9.
Chu C-M, Yao C-T, Chang Y-T, Chou H-L, Chou Y-C, Chen K-H, Terng H-J, Huang C-S, Lee C-C, Su S-L. Gene expression profiling of colorectal tumors and normal mucosa by microarrays meta-analysis using prediction analysis of microarray, artificial neural network, classification, and regression trees. Disease markers. 2014;2014.
Chang Y-T, Yao C-T, Su S-L, Chou Y-C, Chu C-M, Huang C-S, Terng H-J, Chou H-L, Wetter T, Chen K-H. Verification of gene expression profiles for colorectal cancer using 12 internet public microarray datasets. World Journal of Gastroenterology: WJG. 2014;20(46):17476. (First author)
Chang Y-T, Huang C-S, Yao C-T, Su S-L, Terng H-J, Chou H-L, Chou Y-C, Chen K-H, Shih Y-W, Lu C-Y. Gene expression profile of peripheral blood in colorectal cancer. World journal of gastroenterology: WJG. 2014;20(39):14463.
Chou H-L, Yao C-T, Su S-L, Lee C-Y, Hu K-Y, Terng H-J, Shih Y-W, Chang Y-T, Lu Y-F, Chang C-W. Gene expression profiling of breast cancer survivability by pooled cDNA microarray analysis using logistic regression, artificial neural networks and decision trees. BMC bioinformatics. 2013;14(1):1-11.
Wu MA, Pang Y-K, Lin Y, Kuo M-H, Chen K-H, Wu Y-S, Wu H-Y, Chang Y-T, Chang Y-T, Cheng C-S. Usability of Wearable Devices With a Novel Cardiac Force Index for Estimating the Dynamic Cardiac Function: Observational Study.
Chu C-M, Chang Y-T, Wetter T, editors. Artificial neural network may perform good to predict the survivability of cervical cancer2006: American Medical Informatics Association.

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