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Grade(s): 11-12
Length: one semester
Credit: 0.5
Prerequisites: Teacher recommendation or Biology and Human Anatomy and Physiology
Course Overview:
Course Overview:
Intro to Basic Pathophysiology applies knowledge of normal human anatomy and physiology to promote a clear understanding of common disease processes. The course will review basic cellular function, tissue types, and body systems to compare to the body’s response to injury or illness. This course is highly recommended for students interested in pursuing a career in health science.
Adopted Textbook: Human Disease. Delmar, 2015
Adopted Textbook: Human Disease. Delmar, 2015
Units
Units
(Recommended Order)
Semester:
Semester:
Introduction to Basic Pathophysiology and Mechanism of Disease
Neoplasms/ Cancer
Heart Disease - Cardiovascular System
Immune Systems - Our Body's Defense and Treatment
Microorganisms as Infectious Agents
Pharmacology and Drug Development
Hereditary/ Genetic Disorders
Unit 1: Introduction to Basic Pathophysiology and Mechanism of Disease
Unit 1: Introduction to Basic Pathophysiology and Mechanism of Disease
Suggested Pacing: 2-3 weeks
Textbook Chapters/Lessons: Chapter 1
Key Objectives:
Key Objectives:
Review A&P body systems, tissue types, homeostasis, and medical terminology
Understand Pathology: acute vs. chronic disease, signs vs symptoms, eitology, pathogenesis, morphology, and prognosis
Mechanisms of Disease: heredity, trauma, infection/inflammation, hyperplasias/neoplasms, nutritional imbalance, and impaired immunity
Suggested Activities & Resources:
Suggested Activities & Resources:
Create and label a life size body poster
Research diseases of the tissure types
Use prefix, root words, and suffixes to build medical terms
Define and practice terms with case studies
Choose a system (ex. skeletal system) and disease of that system and research the pathology
Practice application of terms with case studies
Practice application of terms with case studies
Case study: When eating makes you sick (Inflammatory Bowel Syndrome)
Scientific Process of Diagnosis Lab
This Podcast Will Kill You
Standards List: Structure and Function: HS-LS1-1, HS-LS1-2, HS-LS1-3
Unit 2: Neoplasms/ Cancer
Unit 2: Neoplasms/ Cancer
Suggested Pacing: 1-2 weeks
Textbook Chapters/Lessons: Chapter 2
Key Objectives:
Key Objectives:
What is cancer, how are cancer cells different than normal cells, causes, statistics, and treatments (current and future)
Types of cancer and current cancer research
Cancer risk factors and preventative measures
Suggested Activities & Resources:
Suggested Activities & Resources:
Cancer stations (explore different topics)
Independent research and presentations
TED Talk and partner share
Interactive website
Cancer sniffing dogs and ants
Standards List: Structure and Function: HS-LS1-1, HS-LS1-2, HS-LS1-3; Inheritance and Variation of Traits: HS-LS1-4, HS-LS3-1, HS-LS3-2, HSLS3-3; Natural Selection and Evolution: HS-LS4-1, HS-LS4-2, HS-LS4-3, HS-LS4-4, HS-LS4-5
Unit 3: Heart Disease - Cardiovascular System
Unit 3: Heart Disease - Cardiovascular System
Suggested Pacing: 2-3 weeks
Textbook Chapters/Lessons: Chapter 8
Key Objectives:
Key Objectives:
Review Cardiovascular system anatomy and physiology
Heart disease is the number 1 killer. Learn the signs, symptoms, risk factors and treatments.
Suggested Activities & Resources:
Suggested Activities & Resources:
Heart and blood flow stop motion video
Build a heart model from clay
Case studies of risk factors
Read ECGs
Virtual cardiology Lab-HHMI Biointeractive
Live from the Heart (case study and open heart surgery video)
Standards List: Structure and Function: HS-LS1-1, HS-LS1-2, HS-LS1-3; Inheritance and Variation of Traits: HS-LS1-4, HS-LS3-1, HS-LS3-2, HSLS3-3; Natural Selection and Evolution: HS-LS4-1, HS-LS4-2, HS-LS4-3, HS-LS4-4, HS-LS4-5
Unit 4: Immune System - Our Body's Defense and Treatment
Unit 4: Immune System - Our Body's Defense and Treatment
Suggested Pacing: 2 weeks
Textbook Chapters/Lessons: Chapter 4 and 5
Key Objectives:
Key Objectives:
Understand the inflammatory response, and innate vs adaptive immunity including the cells of the immune system (neutrophil, macrophage, T-cells, B-cells, antibodies, memory B-cells)
Diseases of the immune system
Suggested Activities & Resources:
Suggested Activities & Resources:
Sutures and wound healing
Immune system comic
Blood typing simulation lab
Research and presentations
Case study
Standards List: Structure and Function: HS-LS1-1, HS-LS1-2, HS-LS1-3; Interdependent Relationships in Ecosystems: HS-LS2-7, HS-LS3-1, HSLS3-2, HS-LS3-3; Natural Selection and Evolution: HS-LS4-1, HS-LS4-2, HS-LS4-3, HS-LS4-4, HS-LS4-5
Unit 5: Microorganisms As Infectious Agents
Unit 5: Microorganisms As Infectious Agents
Suggested Pacing: 2-3 weeks
Textbook Chapters/Lessons:
Key Objectives:
Key Objectives:
Bacteria as an infectious agent: structure, reproduction, size, mode of transmission, types of diseases
Viruses as an infectious agent: structure, reproduction, size, mode of transmission, types of diseases
Protozoans as an infectious agent: structure, reporduction, size, mode of transmission, types of diseases
Fungi as an infectious agent: structure, reproduction, size, mode of transmission, types of diseases
Helminths as infectious agent: structure, reproduction, size, mode of transmission, types of diseases
Suggested Activities & Resources:
Suggested Activities & Resources:
Research specific disease, presentation (Battle of Infectious Diseases in March Madness format)
Culture bacterial plates
Standards List: Structure and Function: HS-LS1-1, HS-LS1-2, HS-LS1-3; Matter and Energy in Organisms and Ecosystems: HS-LS1-6, HS-LS1-7, HS-LS2-4; Inheritance and Variation of Traits: HS-LS1-4, HS-LS3-1, HS-LS3-2, HS-LS3-3; Interdependent Relationships in Ecosystems: HS-LS2-7, HS-LS3-1, HS-LS3-2, HS-LS3-3; Natural Selection and Evolution: HS-LS4-1, HS-LS4-2, HS-LS4-3, HS-LS4-4, HS-LS4-5
Unit 6: Pharmacology and Drug Development
Unit 6: Pharmacology and Drug Development
Suggested Pacing: 2-3 weeks
Textbook Chapters/Lessons:
Key Objectives:
Key Objectives:
Development and types of vaccines. How do vaccines work and what diseases do we have vaccines for?
Antibiotics- how they work, antibiotic resistance, replacing, antibiotics with bacteriphage therapy
Drug Development- the process of clinical trials, and the careers associated witht he development of new pharmaceuticals
Suggested Activities & Resources:
Suggested Activities & Resources:
NOVA- Vaccines, Calling the Shots
Research the diseases vaccines prevent
On cultured bacteria, place antibiotic discs and view zone of inhibition
Antibiotic Resistance Simulation: http://antibiotics.inquiry-hub.net
Gram positive vs gram negative bacteria
HIV Drug Development role play
Standards List: Structure and Function: HS-LS1-1, HS-LS1-2, HS-LS1-3; Matter and Energy in Organisms and Ecosystems: HS-LS1-6, HS-LS1-7, HS-LS2-4; Inheritance and Variation of Traits: HS-LS1-4, HS-LS3-1, HS-LS3-2, HS-LS3-3; Interdependent Relationships in Ecosystems: HS-LS2-7, HS-LS3-1, HS-LS3-2, HS-LS3-3; Natural Selection and Evolution: HS-LS4-1, HS-LS4-2, HS-LS4-3, HS-LS4-4, HS-LS4-5
Unit 7: Hereditary/ Genetic Disorders
Unit 7: Hereditary/ Genetic Disorders
Suggested Pacing: 1 week
Textbook Chapters/Lessons: Chapter 19
Key Objectives:
Key Objectives:
Understand the pathogenesis of congenital, chromosomal, and genetic diseases/disorders.
Suggested Activities & Resources:
Suggested Activities & Resources:
Case Studies
Karyotype lab ( chromosomal disorders)
Research genetic disorder, present of share
Standards List: Inheritance and Variation of Traits: HS-LS1-4, HS-LS3-1, HS-LS3-2, HS-LS3-3; Natural Selection and Evolution: HS-LS4-1, HS-LS4-2, HS-LS4-3, HS-LS4-4, HS-LS4-5
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