Publications

55. Oxygenated Solanapyrone Analogs From Nigrospora sp. IQ-064, a Mangrove Associated Fungus

Fajardo-Hernández Carlos A. , Aguilar-Colorado Ángel Sahid , Corona-Cabello Leslie Maribel, Martínez-Aldino Ingrid Y. , Rivera-Chávez José* 

Chemistry and Biodiversity, 2025

DOI: 10.1002/cbdv.202501912 

54. Rational design of indolyl acrylamides as antibacterial agents targeting multidrug-resistant Acinetobacter baumannii strains 

Domínguez-Méndez Velvett Guadalupe , Chávez-Santos Rosa María , Carrillo-Jaimes Karol, Hernández-Santoyo Alejandra , Ramírez-Carreto Santos, Hernández-García Armando, Aguayo-Ortiz Rodrigo, Corina Ceapa Diana, Rivera-Chávez José, Martínez Roberto

RSC Medicinal Chemistry, 2025

DOI: 10.1039/D5MD00145E 

53. Estimation of Proximal Tubular Function by Stimulation of Organic Anion and Cation Transporters 

Madero Magdalena, Fernández-Yépez Ana Karen, Reséndiz-Albor Aldo Arturo, Rivera-Chávez José , Seegmiller Jesee C, Rodríguez Iturbe Bernardo 

Journal of the American Society of Nephrology, 2025

DOI: 10.1681/ASN.0000000686 

52. DMSO induces the production of dimeric ent-epoxyquinols in Pestalotipsis sp. IQ-011 

Aguilar-Ramírez Enrique , Rivera-Chávez José*, Miranda-Rosas Mario Yair , Martínez-Otero Diego

Organic & Biomolecular Chemistry, 2025

DOI: 10.1039/D5OB00115C

51. Harnessing Molecular and Bioactivity Network Analysis to Prioritize Antibacterial Compound Isolation from Ant-Associated Fungi 

Aguilar-Colorado Ángel S., Rivera-Chávez José*, Morales Jiménez Jesús 

Phytochemical Analysis, 2025

DOI: 10.1002/pca.3513 

50. Roseoglobuloside A, a novel nonanolide and repurposing hPTP1B1-400 inhibitors from mangrove-dwelling Aspergillus spp. 

Fajardo-Hernández Carlos A., Zavala-Sierra Ángeles G., Merlin-Lucas Verenice I., Morales-Jiménez Jesús I., and José Rivera-Chávez*

Planta Medica, 2025

DOI: 10.1055/a-2515-9491

49. The Nicotiana tabacum UGT89A2 enzyme catalyzes the glycosylation of di- and trihydroxylated benzoic acid derivatives 

Duque-Ortiz Arianna, Rivera-Chávez José, Pastor-Palacios Guillermo, Lara-González  

Phytochemistry, 2024

DOI: 10.1016/j.phytochem.2024.114203 

48. DMSO suppresses duclauxin biosynthetic pathway in Talaromyces sp. (strain IQ-313) and untaps terpenoids, polyketides and meroterpenoids biosynthesis 

Aguilar-Ramírez Enrique, Rivera-Chávez José*, Abogado-Aponte Valeria, Quiroz-García Beatriz, y Romo-Pérez Adriana 

Tetrahedron, 2024

DOI: 10.1016/j.tet.2024.134283 

47. N-acyl-4-arylaminopiperidines: Design and synthesis of a potential antimicrobial scaffold 

Ramírez Trinidad Angel, Tovar-Roman Cesar E., Rivera-Chávez José, Huerta-Salazar Elizabeth y Hernández-Vázquez Eduardo 

Bioorganic & Medicinal Chemistry Letters, 2024

DOI: 10.1016/j.bmcl.2024.129936 

46. Exploring the nonenzymatic origin of duclauxin-like natural products 

Aguilar-Ramírez Enrique, Rivera-Chávez José*, Alvarado-Zacarías Brandon D. and Barquera-Lozada José E.  

Journal of Natural Products , 2024

DOI: 10.1021/acs.jnatprod.4c00558 

45. Synthesis, antibiofilm activity and molecular docking of N-acylhomoserine lactones containing cinammic moieties  

Ramírez-Trinidad Ángel, Martínez-Solano Ernesto, Tovar-Román César E., García-Guerrero Mariana, Rivera-Chávez José and Eduardo Hernández-Vázquez 

Bioorganic & Medicinal Chemistry Letters , 2024

DOI: 10.1016/j.bmcl.2023.129592 

44. Antivirulence and antipathogenic activity of Mayan herbal remedies against Pseudomonas aeruginosa 

Espíndola-Rodríguez Nadine Heidi, Muñoz-Cázares Naybi, Serralta-Peraza Lidia Estér del Socorro, Díaz-Núñez José L., Montoya-Reyes Francisco, García-Contreras Rodolfo, Díaz Guerrero Miguel, Rivera-Chávez José, Gutiérrez Jorge, Sotelo-Barrera Mireya, Catillo-Juárez Israel 

Journal of Ethnopharmacology, 2024

DOI: 10.1016/j.jep.2024.118373

43. Antibacterial Activity and AbFtsZ Binding Properties of Fungal Metabolites Isolated from Mexican Mangroves

Carrillo-Jaimes Karol, Fajardo-Hernández Carlos, Hernández-Sedano Fernanda, Cano-Sánchez Patricia, Morales-Jiménez Jesús, Quiroz-García Beatriz, and Rivera-Chávez José*

Revista Brasileira de Farmacognosia, 2024

DOI: 10.1007/s43450-023-00507-2 

42. Efficacy of a Mexican folk remedy containing cuachalalate (Amphipterygium adstringens (Schltdl.) Schiede ex Standl) for the treatment of burn wounds infected with Pseudomonas aeruginosa

Gómez-Salgado María del Rosario Hortencia, Beltrán-Gómez José Ángel,  Díaz-Nuñez José Luis,  Rivera-Chávez José,  García-Contreras Rodolfo,  Estrada- Velasco Ángel Yahir,  Quezada Héctor, Serrano Bello Carlos Alberto, and Castillo-Juárez Israel 

Journal of Ethnopharmacology, 2024

DOI: 10.1016/j.jep.2023.117305 

41. Harnessing the Reactivity of Duclauxin toward Obtaining hPTP1B1–400 Inhibitors

Aguilar-Ramírez Enrique, Reyes-Pérez Valeria, Fajardo-Hernández Carlos, Quezada-Suaste Carlos, Carreón-Escalante Mario, Merlin-Lucas Verenice, and Rivera-Chávez José*

Journal of Medicinal Chemistry , 2023

DOI: 10.1021/acs.jmedchem.3c01594 

40. Integrating Taxonomic and Chemical Diversity of Mangrove-Associated Ascomycetes to Discover or Repurpose Bioactive Natural Products

Martínez Aldino Ingrid Yadira, Rivera-Chávez José*, and Jesús Morales-Jiménez

Journal of Natural Products , 2023

DOI: 10.1021/acs.jnatprod.3c00490 

39. Ants/Nest‑Associated Fungi and Their Specialized Metabolites: Taxonomy, Chemistry, and Bioactivity

Aguilar-Colorado Ángel Sahid, Rivera-Chávez José*

Revista Brasileira de Farmacognosia , 2023

DOI: 10.1007/s43450-023-00417-3 

38. Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma-derived metabolite cues

Kyle Katheleen. E., Puckett Sara. P., Caraballo-Rodríguez Andrés. M., Rivera-Chávez, José., Samples Robert. M., Earp Cody. E., ... , Balunas, Marcy

Medicinal Chemistry Research , 2023

DOI: 10.1073/pnas.2219373120 

37. neo-Clerodane and tiliifolane-type diterpenoids, and other constituents from Salvia pennellii

Sepúlveda-Cuellar Ana Laura, Cárdenas Jorge, Toscano Ruben A., Rivera-Chávez José, Bautista Elihú, Bedolla-García Brenda Y., Flores Joel.

Tetrahedron Letters , 2023

DOI: 10.1016/j.tetlet.2023.154491

36. Synthesis and cytotoxic/antimicrobial screening of 2-alkenylimidazo[1,2-a] pyrimidines 

Ramírez-Trinidad Ángel, Carrillo-Jaimes Karol, Rivera-Chávez José, Hernández-Vázquez Eduardo

Medicinal Chemistry Research , 2023

DOI: 10.1007/s00044-022-02997-6 

35. Cytotoxic constituents of Glycosmis ovoidea collected in Vietnam

Blanco-Carcache Peter J., Anaya-Eugenio Gerardo D., Ngoc Ninh Tran, Moore Curtis E., Rivera-Chávez José, Ren Yulin, Soejarto Djaja D., Kinghorn Douglas A.

Fitoterapia, 2022

DOI: 10.1016/j.fitote.2022.105265 

34. Jatrophenediol, a pseudoguaiane sesquiterpenoid from Jatropha dioica rhizomes

Bautista Elihú, Lozano-Gamboa Sarahí, Fragoso-Serrano Mabel, Rivera-Chávez José, Salazar-Olivo Luis A.

Tetrahedron Letters, 2022

DOI: 10.1016/j.tetlet.2022.154040 

33. Biological dark matter exploration using data mining for the discovery of antimicrobial natural products

Rivera-Chávez José*, Ceapa Diana-Corina, Figueroa Mario

Planta Medica, 2022

DOI: 10.1055/a-1795-0562 

32. Crystal structures and study of interaction mode of bis-benzimidazole-benzene derivatives with DNA

Valdes-García Josue, Viviano-Posadas Alejandro,  Rivera-Chávez José, Ramírez-Apan Teresa,  Martínez-Vargas Sergio, Aguirre-Hernández Eva, German-Acacio Juan M., Morales-Morales David, Dorazco-González Alejandro 

Journal of Molecular Structure, 2021

DOI: 10.1016/j.molstruc.2021.131582 

31. Absolute configuration and protein tyrosine phosphatase 1B inhibitory activity of xanthoepocin, a dimeric naphtopyrone from Penicillium sp. IQ-429

Martínez-Aldino Ingrid Y., Villaseca-Murillo Martha, Morales-Jiménez Jesús, and Rivera-Chávez José*

Bioorganic Chemistry, 2021

DOI: 10.1016/j.bioorg.2021.105166 

30. Clerodane and 5 10-Seco-Clerodane-type diterpenoids from Salvia involucrata

Bustos-Brito Celia, Pérez-Juanchi Diana, Rivera-Chávez José, Hernández-Herrera Alejandro David, Bedolla-García Brenda Y., Zamudio Sergio, Ramírez-Apan, Quijano Leovigildo,  and Esquivel Baldomero

Journal of Molecular Structure, 2021

DOI: 10.1016/j.molstruc.2021.130367

29. Protein tyrosine phosphatase 1B inhibitors from the fungus Malbranchea albolutea

Díaz-Rojas Miriam, Raja Huzefa, González-Andrade Martín, Rivera-Chávez José, Rangel-Grimaldo Manuel, Rivero-Cruz Isabel and Mata Rachel

Phytochemistry, 2021

DOI: 10.1016/j.phytochem.2021.112664

28. Tetradecanoic acids with anti-virulence properties increase the pathogenicity of Pseudomonas aeruginosa in a murine cutaneous infection model

Juárez-Rodríguez  Martha María,  Cortes-López Humberto, García-Contreras Rodolfo,  González-Pedrajo Bertha,  Díaz-Guerrero Miguel A., Martínez-Vázquez Mariano,  Rivera-Chávez José,  Soto-Hernández  Marcos and Castillo-Juárez Israel

Frontiers in Cellular and Infection Microbiology, 2020

DOI: 10.3389/fcimb.2020.597517 

27. Apoptosis induced by (+)-betulin through NF-ĸB inhibition in MDA-MB-231 breast cancer cells 

Anaya-Eugenio Gerardo D., Eggers Nicole A., Ren Yulin, Rivera-Chávez José, Douglas Kinghorn and Carcache de Blanco Esperanza J.

Anticancer Research,  40, 6637-6647, 2020

DOI: 10.21873/anticanres.14688 

26. One step partial synthesis of (±)-asperteretone B and related hPTP1B1-400 inhibitors from butyrolactone I 

Rivera-Chávez José *, Coporo-Blancas Diego and Morales-Jiménez Jesús 

Bioorganic and Medicinal Chemistry, 28, 24, 115817, 2020 

DOI: 10.1016/j.bmc.2020.115817

25. Phenethyisoquinoline alkaloids from the leaves of Androcymbium palaestinum

El-Elimat Tamam, Alhawarri Maram B., Rivera-Chávez José, Burdette Joanna E., Czarnecki Austin, Al-Gharaibeh Mohammad, Al-Sharie Ahmed H., Alhusban Ahmed, Alali Feras Q. and Oberlies Nicholas H.

Fitoterapia, 146, 104706, 2020

DOI: 10.1016/j.fitote.2020.104706 

24. Antinociceptive and anxiolytic-like effects of a neoclerodane diterpene from Salvia semiatrata aerial parts 

Ortiz-Mendoza Nancy, Zavala-Ocampo Lizeth M., Martínez Gordillo Martha J., González-Trujano María Eva, Basurto Peña Francisco A., Bazany-Rodríguez Iván J., Rivera-Chávez José, Dorazco-González Alejandro and Eva Aguirre-Hernández

Pharmaceutical Biology, 58(1), 620-629, 2020

DOI: 10.1080/13880209.2020.1784235

23. Hydroxy-neo-clerodanes and 5,10-seco-neo-clerodanes from Salvia decora 

Rivera-Chávez José*, Bustos-Brito Celia, Aguilar-Ramírez Enrique, Martínez-Otero Diego, Rosales-Vázquez Luis D., Dorazco González Alejandro and Cano-Sánchez Patricia

Journal of Natural Products, 83(7), 2212-2220, 2020 

DOI: 10.1021/acs.jnatprod.0c00313  

22. Dimeric phenalenones from Talaromyces sp. (IQ-313) inhibit hPTP1B1-400: Insights into mechanistic kinetics from in vitro and in silico studies

Jiménez-Arreola Brenda S., Aguilar-Ramírez Enrique, Cano-Sánchez Patricia, Morales-Jiménez Jesús, González-Andrade Martín, Medina-Franco José L., and Rivera-Chávez José* 

Bioorganic Chemistry, 101, 103893, 2020

DOI: 10.1016/j.bioorg.2020.103893 

21. Structural Elucidation of Malonylcommunol and 6β-Hydroxy-trans-communic Acid, Two Undescribed Diterpenes from Salvia cinnabarina. First Examples of Labdane Diterpenoids from a Mexican Salvia Species

Bustos-Brito Celia, Nieto-Camacho Antonio, Hernandez-Ortega Simón, Rivera-Chávez José, Quijano Leovigildo and Esquivel Baldomero 

Molecules, 25, 2-17, 2020

DOI: 10.3390/molecules25081808 

20. Drug Leads from Endophytic Fungi: Lessons Learned via Scaled Production

Graf Tyler N., Kao Diana, Rivera-Chávez José, Gallagher Jacklyn M., Raja Huzefa A., and Oberlies Nicholas H. 

Planta Medica, 86(13-14), 988-996, 2020 

DOI: 10.1055/a-1130-4856

19. Syntaxin 6-mediated Exosome Secretion Regulates Enzalutamide Resistance in  Prostate Cancer 

Peak Taylor C., Panigrah Gati K., Praharaj Prakash P., Su Yixin, Shi Lihong, Chry Jacqueline, Rivera-Chávez José, Flores-Bocanegra Laura, Singh Ravi, Vander Griend Donald, J., Oberlies Nicholas H., Kerr Bethany A., Hemal Ashok, Bitting Rhonda L. and Deep Gagan  

Molecular Carcinogenesis, 59(1), 62-72, 2020 

DOI: 10.1002/mc.23129 

18. Cuautepestalorin, a 7,8-Dihydrochromen-Oxoisochromane Adduct Bearing a Hexacyclic Scaffold from Pestalotiopsis sp. IQ-011 

Rivera-Chávez José*, Zacatenco-Abarca Jade, Morales-Jiménez Jesús, Martínez-Aviña Blanca, Hernández-Ortega Simón, y Aguilar-Ramírez Enrique  

Organic Letters, 21(1), 3558-3562, 2019 

DOI: 10.1021/acs.orglett.9b00962  

17. Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing 

Paguigan Noemi D., Rivera-Chávez José, Stempin Justin J., Augustinović Mario, Noras Aleksandra I., Raja Huzefa A., Todd Daniel A., Triplett Kathleen D., Day Cynthia, Figueroa Mario, Hall Pamela R., Cech Nadja B. and Oberlies Nicholas H. 

Journal of Natural Products, 82(3), 550-558, 2019 

DOI: 10.1021/acs.jnatprod.8b00925 

16. Mycopyranone: A 8,8ˈ-binaphthopyranone with potent anti-MRSA activity from the fungus Phialemoniopsis sp.  

Rivera-Chávez José, Caesar Lindsay K., Garcia-Salazar Juan J., Raja Huzefa A., Cech Nadja B., Pearce Cedric J., y Oberlies Nicholas H.  

Tetrahedron Letters, 60(8), 594-597, 2019 

DOI: 10.1016/j.tetlet.2019.01.029 

15. Delitpyrones: α-Pyrone Derivatives from a Freshwater Delitschia sp.

Rivera-Chávez José, El-Elimat Tamam, , Gallagher Jacklyn M., Graff Tyler N., Fournier Jacques, Panigrahi Gati K., Bunch Rick L., Raja Huzefa and Oberlies Nicholas H.

Planta Medica, 85, 62-71, 2019

DOI: 10.1055/a-0654-5850 

14. The Value of Universally Available Raw NMR Data for Transparency, Reproducibility, and Integrity in Natural Product Research

McAlpine James B., Chen Shao-Nong, Kutateladze Andrei, MacMillan John B., Appendino Giovanni, Barison Andersson, Beniddir Mehdi A., Biavatti Maique W., Bluml Stefan, Asmaa Boufridi, Butler Mark S., Capon Robert J., Choi Young H., Coppage David, Crews Phillip, Crimmins Michael T., Csete Marie, Dewapriya Pradeep, Egan Joseph M., Garson Mary J., Genta-Jouve Gregory, Gerwick William H. Gross Harald, Harper Mary Kay, Hermanto Precilia, Hook James M., Hunter Luke, Jeannerat Damien, Ji Nai-Yun, Johnson Tyler A., Kingston David G. I., Koshino Hiroyuki, Lee Hsiau-Wei, Lewin Guy, Li Jie, Linington Roger G., Liu Miaomiao, McPhail Kerry L., Molinski Tadeusz F., Moore Bradley S., Nam Joo-Won, Neupane Ram P., Niemitz Matthias, Nuzillard Jean-Marc, Oberlies Nicholas H., Ocampos Fernanda M. M., Pan Guohui, Quinn Ronald J., Reddy D. Sai Renault Jean-Hugues, Rivera-Chévez José, Robien Wolfgang, Saunders Carla M., Schmidt Thomas J., Seger Christoph, Shen Ben, Steinbeck Christoph, Stuppner Hermann, Sturm Sonja, Taglialatela-Scafati Orazio, Tantillo Dean J., Verpoorte Robert, Wang Bin-Gui, Williams Craig M., Philip G. Williams, Wist Julien, Yue Jian-Min, Zhang Chen, Xu Zhengren, Simmler Charlotte, David C. Lankin, Bisson Jonathan, Guido F. Pauli

Natural Products Reports, 36, 36-107, 2019

DOI: 10.1039/C7NP00064B 

13. Development and Utilization of a Palladium-Catalyzed Dehydration of Primary Amides To Form Nitriles

Al-Huniti Mohammed H., Rivera-Chávez José, Colón Katsuya L., Stanley Jarrod., Burdette Joanna E., Pearce Cedric C., Oberlies Nicholas H. and Croatt Mitchell P.

Organic Letters, 20, 19, 6046-6050, 2018

DOI: 10.1021/acs.orglett.8b02422 

12. Cytotoxic homoisoflavonoids from the bulbs of Bellevalia flexuosa

El-Elimat Tamam, Rivera-Chávez José, Burdette Joanna E., Czarnecki Austin., Alhawarri Maram B., Al-Garaibeh Mohammad., Alali Feras and Oberlies Nicholas H.

Fitoterapia, 127, 201-206, 2018

DOI: 10.1016/j.fitote.2018.02.022

11. Prealamethicin F50 and related peptaiblos from Trichoderma arundinaceum: Validation of their authencticity via MS in situ analysis

Rivera-Chávez José, Raja Huzefa A., Graf Tyler N., Gallagher Jacklyn M., Metri Prashant., Xue Ding., Pearce Cedric J. and Oberlies Nicholas H.

RSC Advances, 7, 45733-45741, 2017

DOI: 10.1039/C7RA09602J 

10. Biosynthesis of Fluorinated Peptaibols Using a Site Directed Building Block Incorporation Approach

Rivera-Chávez José, Raja Huzefa A., Graf Tyler N., Burdette Joanna E., Pearce Cedric J. and Oberlies Nicholas H.

Journal of Natural Products, 80, 1883-1892, 2017

DOI: 10.1021/acs.jnatprod.7b00189 

9. In situ mass spectrometry monitoring of fungal cultures led to the identification of four peptaibols with a rare threonine residue

Sica Vincent P., Rees Evan R., Raja Huzefa A., Rivera-Chávez José, Burdette Joanna E., Pearce Cedric J. and Oberlies Nicholas H.

Phytochemistry, 143, 45-53, 2017

DOI: 10.1016/j.phytochem.2017.07.004

8. Secondary Metabolites from the Leaves of the Medicinal Plant Goldenseal (Hydrastis canadensis)

Leyte-Lugo Martha, Britton Emily R., Foil Daniel H., Brown Adam R., Todd Daniel A., Rivera-Chávez José, Oberlies Nicholas H. and Cech Nadja B.

Phytochemistry Letters, 20, 54-60, 2017

DOI: 10.1016/j.phytol.2017.03.012

7. Review of The Assignment of the Absolute Configuration by NMR Using Chiral Derivatizing Agents: A Practical Guide

Oberlies H. Nicholas and Rivera-Chávez José

Journal of Natural Products, 80, 1231-1231, 2017

DOI: 10.1021/acs.jnatprod.7b00122 

6. Insights into molecular interactions between CaM and its inhibitors from molecular dynamics simulations and experimental data

González-Andrade Martín, Rodríguez Sotres Rogelio, Madariaga-Mazón Abraham, Rivera-Chávez José, Mata Rachel, Sosa Peinado Alejandro, Del Pozo-Yauner Luis, and Arias-Olguín Amilla I

Journal of Biomolecular Structure and Dynamics,  34, 78-91, 2016

DOI: 10.1080/07391102.2015.1022225

5. Calmodulin inhibitors from natural sources: An update

Mata Rachel, Figueroa Mario, González-Andrade Martín, Rivera-Chávez José, Madariaga-Mazón Abraham and Del Valle Pérez Paulina.

Journal of Natural Products, 78, 576-586, 2015

DOI: 10.1021/np500954x 

4. α-Glucosidase Inhibitors from a Xylaria feejeensis Associated with Hintonia latiflora

Rivera-Chávez José, Figueroa Mario, González Villaseñor María del Carmen, Glenn Anthony E. and Mata Rachel.

Journal of Natural Products, 78, 730-735, 2015

DOI: 10.1021/np500897y 

3. Hypoglycemic properties of some preparations and compounds from Artemisia ludoviciana Nutt.

Anaya-Eugenio Gerardo, Rivero-Cruz Isabel, Rivera-Chávez José and Mata Rachel

Journal of Ethnopharmacology, 155, 416-425, 2014

DOI: 10.1016/j.jep.2014.05.051

2. Thielavins A, J and K: α-Glucosidase inhibitors from MEXU 27095, an endophytic fungus from Hintonia latiflora

Rivera-Chávez José, González-Andrade Martin, González Villaseñor María del Carmen, Glenn Anthony E. and Mata Rachel

Phytochemistry, 94, 198-205, 2013

DOI: 10.1016/j.phytochem.2013.05.021

1. Development of the Fluorescent Biosensor hCalmodulin (hCaM)L39C-monobromobimane(mBBr)/V91C-mBBr, a Novel Tool for Discovering New Calmodulin Inhibitors and Detecting Calcium

González-Andrade Martin, Rivera-Chávez José, Sosa-Peinado Alejandro, Figueroa Mario, Rodríguez-Sotres Rogelio, and Mata Rachel.

Journal of Medicinal Chemistry, 54, 3875-3884, 2011

DOI: 10.1021/jm200167g