Our interdisciplinary research group specializes in the field of nanotechnology and its applications in various biomedical disciplines. Our specific thrust areas of research includes theranostic nanomaterials, interfacial nano-bio interactions, tissue engineering, nanocarrier design, ultrasound-responsive systems and bioactive nanofibers.Â
Interfacial Nano-bio Interactions of Biomaterials - Understanding the interactions between nanomaterials and biological systems is vital for the development of safe and effective biomaterials. We investigate such critical interactions through meticulous analysis of molecular-level interactions between nanomaterials and cells, proteins, and tissues and deduce their implications on biocompatibility and functionality of biomaterials for various applications.
Theranostic Nanomaterials - Theranostic nanomaterials refer to a class of multifunctional nanoparticles or nanomaterials that combine therapeutic and diagnostic capabilities within a single platform. Our research primarily revolves around the synthesis and characterization of theranostic nanomaterials by diverse synthetic approaches and explores the potential of these nanomaterials for targeted drug delivery, imaging, and monitoring of diseases.
Hybrid Functional Nanofibers - Our research includes design and synthesis of bioactive nanofibers, metal composites, and polymeric nanoparticles. These nanomaterials exhibit unique properties and functionalities, finding applications in diverse biomedical fields such as tissue engineering, drug delivery, and biosensing. We seek to optimize the performance of these materials through careful tailoring of their composition, morphology, and surface properties.
3D Dynamic Scaffolds for Tissue Engineering - We also specializes in the design and fabrication of 3D dynamic scaffolds that closely mimic the natural extracellular matrix. By incorporating dynamic properties such as mechanical stimuli and controlled release systems, his research aims to optimize cellular behavior and facilitate tissue regeneration. This multidisciplinary approach combines materials science, engineering, and biology to advance the field of tissue engineering.
Ultrasound Responsive Nanocarriers for Regenerative medicine - These nanocarriers are designed to respond to ultrasound stimulation by releasing their payload at the desired location, offering a non-invasive and site-specific approach to deliver therapeutic substances. The basic concept behind ultrasound-responsive nanocarriers involves incorporating ultrasound-sensitive components into the nanocarrier structure. These components can include microbubbles, nanoparticles, liposomes, or hydrogels that respond to ultrasound waves by undergoing physical or chemical changes, leading to the release of the encapsulated therapeutic agents. We explore the potential application of these materials in various applications, such as tissue engineering, wound healing, bone regeneration, and controlled release of growth factors or stem cells.
Neuromodulation by Ultrasound - Ultrasound-mediated neuromodulation refers to a technique that uses ultrasound waves to modulate or influence the activity of neural tissue in the body. The basic principle behind ultrasound-mediated neuromodulation is that ultrasound waves can generate mechanical vibrations in tissue, leading to various effects on neural activity. These effects can include the modulation of action potentials, neuronal firing rates, or the release of neurotransmitters. We seek to understand the mechanism and cellular pathways involved in US mediated neuronal modulation and establish it as a reliable and precise therapeutic tool for treatment of neurodegenerative disesase.