2025
Yichen Feng, Xiaochun Xu, Cody C. Rounds, Sassan Hodge, Kenneth M. Tichauer, Kimberley S. Samkoe. Dynamic tracking of in vivo receptor availability in tumor using paired-agent imaging. Molecular Pharmaceutics. In press.
Cody C. Rounds, Yichen Feng, Sanjana Pannem, Jovan G. Brankov, Kimberley S. Samkoe, Kenneth M. Tichauer. Dual-channel pulse-dye densitometry can enable correction of fluorescent targeted and control agent plasma input function differences for quantitative paired-agent molecular imaging: a simulation study. Journal of Biomedical Optics. 30(4), 046001, 2025.
Sarah R. Vavrek, Elif Kayaalp Nalbant, Nicholas Konopek, Bou-Ghanem, Amani A. Fawzi, William F. Mieler, Kenneth M. Tichauer, Jennifer J. Kang-Mieler. Retinal vascular permeability in diabetic subjects without retinopathy compared to mild diabetic retinopathy and healthy controls. Ophthalmology Science. 5(2), 100636, 2025
2024
Kenneth M. Tichauer*, Priscilla Machado*, Ji-Bin Liu, A. S. Chalmika Sarathchandra, Maria Stanczak, Walter K. Kraft, Flemming Forsberg. Macrophage uptake rate of Sonazoid in breast lymphosonography is highly conserved in healthy controls. Physics in Medicine and Biology. 69(20):205006, 2024 *Authors contributed equally.
Nathan P. McMahon, Allison Solanki, Lei G. Wang, Antonio R. Montaño, Jocelyn A. Jones, Kimberley S. Samkoe, Kenneth M. Tichauer, Summer L. Gibbs. In situ single-cell therapeutic response imaging facilitated by the TRIPODD fluorescence imaging platform. Theranostics. 14(7):2816-2834, 2024.
Chengyue Li, Cody C. Rounds, Veronica C. Torres, Yusheng He, Xiaochun Xu, Georgia Papavasiliou, Kimberley S. Samkoe, Jovan G. Brankov, Kenneth M. Tichauer. Quantifying imaging agent binding and dissociation in 3D cancer spheroid tissue culture using paired-agent principles. Annals of Biomedical Engineering. 52(6):1625-1637, 2024.
Yichen Feng, Sanjana Pannem, Sassan Hodge, Cody Rounds, Kenneth M. Tichauer, Keith D. Paulsen, Kimberley S. Samkoe. Quantitative pharmacokinetic and biodistribution studies for fluorescent imaging agents. Biomedical Optics Express. 15(3):1861-1877, 2024.
Cody C. Rounds, Jaron G. de Wit, Jasper Vonk, Jennifer Vorjohan, Sophia Nelson, Allyson Trang, Brooke Villinski, Kimberley S. Samkoe, Jovan G. Brankov, Floris J. Voskuil, Max J. H. Witjes, Kenneth M. Tichauer. Improved intraoperative identification of close margins in oral squamous cell carcinoma resections using a dual aperture fluorescence ratio approach: first in-human results. Journal of Biomedical Optics. 29(1):016003, 2024
Austin Van Namen, Sidhartha Jandhyala, Catalina-Paula Spatarelu, Kenneth M. Tichauer, Kimberley S. Samkoe, Geoffrey P. Luke. Multiplex ultrasound imaging of perfluorocarbon nanodroplets enabled by decomposition of postvaporization dynamics. Nano Letters. 24(1):209-214, 2024
2023
Cody C. Rounds, Chengyue Li, Wei Zhou, Kenneth M. Tichauer, Jovan G. Brankov. A cadaveric breast cancer tissue phantom for phase-contrast x-ray imaging applications. Animal Models and Experimental Medicine. 6(5):427-432, 2023
Matthew S. Reed, Marien Ochoa, Kenneth M. Tichauer, Ashley Weichmann, Marvin M. Doyley, Brian W. Pogue. Mapping estimates of vascular permeability with a clinical ICG fluorescence imaging system in experimental pancreatic adenocarcinoma tumors. Journal of Biomedical Optics. 28(7):076001, 2023
Lei G. Wang, Antonio R. Montaño, Jason R. Combs, Nathan McMahon, Allison Solanki, Michelle M. Gomes, Kai Tao, William H. Bisson, Dani Szafran-Reeder, Kimberley S. Samkoe, Kenneth M. Tichauer, Summer L. Gibbs. OregonFluor enables quantitative intracellular paired agent imaging (iPAI) to assess drug target availability in live cells and tissues. Nature Chemistry. 15(5):729-739, 2023
Cheng Wang, Sassan Hodge, Divya Ravi, Eunice Y. Chen, P. Jack Hoopes, Kenneth M. Tichauer, Kimberley S. Samkoe. Rapid and quantitative intraoperative pathology-assisted surgery by paired-agent imaging derived confidence map. Molecular Imaging and Biology. 25(1):190-202, 2023
Cheng Wang, Xiaochun Xu, Sassan Hodge, Eunice Y. Chen, P. Jack Hoopes, Kenneth M. Tichauer, Kimberley S. Samkoe. Identification of a suitable untargeted agent for the clinical translation of ABY-029 paired-agent imaging in fluorescence-guided surgery. Molecular Imaging and Biology. 25(1):97-109, 2023
Cheng Wang, Margaret R. Folaron, Sassan Hodge, Eunice Y. Chen, P. Jack Hoopes, Kenneth M. Tichauer, Kimberley S. Samkoe. Improved discrimination of tumors with low and heterogeneous EGFR expression in fluorescence guided surgery through paired-agent protocols. Molecular Imaging and Biology. 25(1):110-121, 2023
2022
Boyu Meng, Negar Sadeghipour, Margaret R. Folaron, Rendall R. Strawbridge, Kimberley S. Samkoe, Kenneth M. Tichauer, Scott C. Davis. Examining the feasibility of quantifying receptor availability using cross-modality paired agent imaging. Molecular Imaging and Biology. 24(1), 23-30, 2022
2021
Nathan P. McMahon, Allison Solanki, Lei G. Wang, Antonio R. Montaño, Jocelyn A. Jones, Kimberley S. Samkoe, Kenneth M. Tichauer, Summer L. Gibbs. TRIPODD: A novel fluorescence imaging platform for in situ quantification of drug distribution and therapeutic response. Molecular Imaging and Biology. 23(5), 650-664, 2021
Veronica C. Torres, Chengyue Li, Jovan G. Brankov, Kenneth M. Tichauer. Model-based system matrix for iterative reconstruction in sub-diffuse angular-domain fluroescence optical projection tomography. Biomedical Optics Express. 12(3), 1248-1262, 2021
Chengyue Li, Veronica C. Torres, Yusheng He, Xiaochun Xu, Yusairah Basheer, Georgia Papavasiliou, Kimberley S. Samkoe, Jovan G. Brankov, Kenneth M. Tichauer. Intraoperative detection of micrometastases in whole excised lymph nodes using fluorescent paired agent imaging principles: identification of a suitable staining and rinsing protocol. Molecular Imaging and Biology. 23(4), 537-549, 2021
Veronica C. Torres, Chengyue Li, Wei Zhou, Jovan G. Brankov, Kenneth M. Tichauer. Characterization of an angular domain fluorescence optical projection tomography system for mesoscopic lymph node imaging. Applied Optics. 60(1), 135-146, 2021
Girgis Obaid*, Kimberley Samkoe*, Shazia Bano, Srivalleesha Mallidi, Yeonjae Park, Zachary Silber, Kenneth M. Tichauer, Brian W. Pogue, Tayyaba Hasan. Optical paired nanotracer imaging (PNI) quantifies engagement of EGFR targeted nanoconstructs with glioblastoma in vivo and provides receptor-specific contrast for image guided surgery. (*authors contributed equally). Nano Research. 14(15):1344-1354, 2021
2020
Negar Sadeghipour, Aakanksha Rangnekar, Margaret R. Folaron, Rendall R. Strawbridge, Kimberley S. Samkoe, Scott C. Davis, Kenneth M. Tichauer. Prediction of optimal contrast times post-imaging-agent-administration to inform personalized fluorescence-guided surgery. Journal of Biomedical Optics. 25(11), 116005, 2020
Boyu Meng, Margaret Folaron, Rendall R. Strawbridge, Negar Sadeghipour, Kimberley S. Samkoe, Kenneth M. Tichauer, Scott C. Davis. Quantitative paired-agent tomographic imaging estimates receptor availability during receptor-targeted therapy. Theranostics. 10(24):11230-11243, 2020
2019
Veronica C. Torres, Chengyue Li, Yusheng He, Lagnojita Sinha, Georgia Papavasiliou, Husain A. Sattar, Jovan G. Brankov, Kenneth M. Tichauer. Angular restriction fluorescence optical projection to localize micrometastases in lymph nodes. Journal of Biomedical Optics. 24(11), 110501, 2019
Brook K. Byrd, Kenneth M. Tichauer, Mikael Marois, Dennis J. Wirth, Jennifer Hong, Joseph P. Leonor, Jonathan T. Elliott, Keith D. Paulsen, Scott C. Davis. First experience imaging second-window infrared (SWIR) fluorescence in a large animal: ICG angiography of a pig brain. Journal of Biomedical Optics. 24(8), 1-4, 2019
Lagnojita Sinha, Francesc Massanes, Chengyue Li, Veronica C. Torres, Kenneth M. Tichauer, Jovan G. Brankov. Comparison of time- and angular-domain scatter rejection in mesoscopic optical projection tomography: a simulation study. Biomedical Optics Express. 10(2), 747-760, 2019
Soyoung Kang*, Xiaochun Xu*, Eric Navarro Comes, Yu Wang, Jonathan T. C. Liu, Kenneth M. Tichauer. Modeling the binding and diffusion of receptor-targeted nanoparticles topically applied on fresh tissue specimens. (*authors contributed equally). Physics in Medicine and Biology. 64(4), 045013, 2019
Chengyue Li, Xiaochun Xu, Nathan McMahon, Omar Alhaj Ibrahim, Husain Sattar, Kenneth M. Tichauer. Paired-agent fluorescence imaging of sentinel lymph node metastases using indocyanine green as a control agent for antibody-based targeted agents. Contrast Media & Molecular Imaging. Article ID: 7561862, 2019
2018
Siyuan Ren, Xiang Sun, Trung Hai Nguyen, Negar Sadeghipour, Xiaochun Xu, Hua Xu, Chi Soo Kang, Yujie Liu, Hua Xu, Ningjie Wu, Yanda Chen, Kenneth Tichauer, David D. L. Minh, Hyun-Soon Chong. Design, synthesis, and biological evaluation of novel polyaminocarboxylate ligand-based theranostic conjugate for antibody-targeted cancer therapy and near-infrared optical imaging. ChemMedChem. 13(24), 2606-2617, 2018
Yusheng He, Daniel Young, Merjem Mededovic, Kevin Li, Chengyue Li, Kenneth M. Tichauer, David Venerus, Georgia Papavasiliou. Protease-sensitive hydrogel biomaterials with independently tuned modulus and adhesion ligand gradients for 3D guided neovascularization. Biomacromolecules. 19(11), 4168-4181, 2018
Chengyue Li, Veronica C. Torres, Kenneth M. Tichauer. Noninvasive detection of cancer spread to lymph nodes: a review of molecular imaging principles and protocols. Journal of Surgical Oncology, 118(2), 301-314, 2018
Negar Sadeghipour, Scott C. Davis, Kenneth M. Tichauer. Correcting for targeted and control agent signal differences in paired-agent molecular imaging of cancer cell-surface receptors, Journal of Biomedical Optics, 23(6), 066004, 2018
Lagnojita Sinha, Morgan Fogarty, Wei Zhou, Andrea Giudice, Jovan G. Brankov, Kenneth M. Tichauer. Design and characterization of a dead-time regime enhanced early photon projection imaging system. Review of Scientific Instruments, 89(4), 043707, 2018
Soyoung Kang, Yu Wang, Xiaochun Xu, Eric Navarro Comes, Kenneth M. Tichauer, Jonathan T. C. Liu. Microscopic investigation of topically applied SERS NPs for Raman-encoded molecular imaging of fresh tissue specimens. Journal of Biophotonics. 11(4), e201700246, 2018
2017
Veronica C. Torres, Victoria D. Vuong, Todd Wilson, Joshua Wewel, Richard W. Byrne, Kenneth M. Tichauer. Cranial nerve contrast using nerve-specific fluorophores improved by paired-agent imaging with indocyanine green as a control agent. Journal of Biomedical Optics, 22(9), 096012, 2017
Xiaochun Xu, Yu Wang, Jialing Xiang, Jonathan T. C. Liu, Kenneth M. Tichauer. Rinsing paired-agent model (RPAM) to quantify cell-surface receptor concentrations in topical staining applications of thick tissues. Physics in Medicine and Biology, 62(12), 5098-113, 2017
Negar Sadeghipour, Scott C. Davis, Kenneth M. Tichauer. Generalized paired-agent kinetic model for in vivo quantification of cancer cell-surface receptors under receptor saturation conditions. Physics in Medicine and Biology, 62(2), 394-414, 2017
2016
Lagnojita Sinha, Jovan G. Brankov, Kenneth M. Tichauer. Enhanced detection of early photons in time-domain optical imaging by running in “dead-time” regime. Optics Letters, 41(14), 3225-8, 2016
2015
Banu Akar, Bin Jiang, Sami I. Somo, Alyssa A. Appel, Jeffrey C. Larson, Kenneth M. Tichauer, Eric M. Brey. Biomaterials with persistent growth factor gradients in vivo accelerate vascularized tissue formation. Biomaterials, 72:61-73, 2015.
Kenneth M. Tichauer, Yu Wang, Brian W. Pogue, Jonathan T. C. Liu. Quantitative in vivo cell-surface receptor imaging in oncology: kinetic modeling & paired-agent principles from nuclear medicine and optical imaging. Physics in Medicine and Biology, 60(14), R239-69, 2015
Kenneth M. Tichauer, Micah Guthrie, Logan Hones, Lagnojita Sinha, Keith St. Lawrence, Jennifer J. Kang-Mieler. Quantitative retinal blood flow mapping from fluorescein videoangiography using tracer kinetic modeling. Optics Letters, 40(10), 2189-92, 2015
Alisha V. DSouza, Jonathan T. Elliott, Jason R. Gunn, Richard J. Barth Jr., Kimberley S. Samkoe, Kenneth M. Tichauer, Brian W. Pogue. Nodal lymph flow quantified with afferent vessel input function allows differentiation between normal and cancer-bearing nodes. Biomedical Optics Express, 6(4):1304-17, 2015
Lagnojita Sinha*, Yu Wang*, Cynthia Yang, Altaz Khan, Jovan G. Brankov, Jonathan T. Liu, Kenneth M. Tichauer. Quantification of the binding potential of cell-surface receptors in fresh excised specimens via dual-probe modeling of SERS nanoparticles. Scientific Reports, 5:8582, 2015 (*authors contributed equally)
Jonathan T. Elliott, Kimberley S. Samkoe, Jason R. Gunn, Errol E. Stewart, Timothy B. Gardner, Kenneth M. Tichauer, Ting-Yim Lee, P. Jack Hoopes, Stephen P Pereira, Tayyaba Hasan, Brian W. Pogue. Perfusion CT estimates photosensitizer uptake and biodistribution in a rabbit orthotopic pancreas cancer model: a pilot study. Academic Radiology, 22(5);572-9, 2015
2014
Kimberley S. Samkoe, Kenneth M. Tichauer, Jason R. Gunn, Wendy A. Wells, Tayyaba Hasan, Brian W. Pogue. Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach. Cancer Research. 74(24):7465-74, 2014
Kenneth M. Tichauer, Kimberley S. Samkoe, Jason R. Gunn, Stephen C. Kanick, P. Jack Hoopes, Richard J. Barth, Peter A. Kaufman, Tayyaba Hasan, Brian W. Pogue. Microscopic lymph node tumor burden quantified by macroscopic dual-tracer molecular imaging. Nature Medicine. 20(11):1348-53, 2014
Stephen C. Kanick, Kenneth M. Tichauer, Kimberley S. Samkoe, Brian W. Pogue. Pixel-based absorption-correction for dual-tracer fluorescence imaging of receptor binding. Biomedical Optics Express. 5(10):3280-3291, 2014
Nazanin Hamzei, Kimberley S. Samkoe, Jonathan T. Elliott, Robert W. Holt, Jason R. Gunn, Ting-Yim Lee, Tayyaba Hasan, Brian W. Pogue, Kenneth M. Tichauer. Comparison of kinetic models for dual-tracer receptor concentration imaging in tumors. Austin Journal of Biomedical Engineering 1(1):9, 2014
Kenneth M. Tichauer, Mamadou Diop, Jonathan T. Elliott, Kimberley S. Samkoe, Tayyaba Hasan, Keith St. Lawrence, Brian W. Pogue. Accounting for pharmacokinetic differences in dual-tracer receptor density imaging. Physics in Medicine and Biology 59(10):2341-2351, 2014 [Highlighted in Medical Physics Web (medicalphysicsweb.org/cws/article/research/57322)]
Jonathan T. Elliott, Kenneth M. Tichauer, Kimberley S. Samkoe, Jason R. Gunn, Kristian J. Sexton, Brian W. Pogue. Direct characterization of tracer plasma curves by fluorescence imaging of exposed carotid artery to facilitate kinetic analysis. Molecular Imaging and Biology. 16(4):488-494, 2014
Kenneth M. Tichauer, Sophie J. Deharvengt, Kimberley S. Samkoe, Jason R. Gunn, Marcus W. Bosenberg, Mary-Jo Turk, Tayyaba Hasan, Radu V. Stan, Brian W. Pogue. Tumor endothelial marker imaging in melanomas using dual-tracer fluorescence molecular imaging. Molecular Imaging and Biology 16(3):372-382, 2014
2013
Scott C. Davis, Kimberley S. Samkoe, Kenneth M. Tichauer, Kristian J. Sexton, Jason R. Gunn, Sophie J. Deharvengt, Tayyaba Hasan, Brian W. Pogue. Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo. Proceedings of the National Academy of Science 110(22):9025-9030, 2013
Kristian J. Sexton, Kenneth M. Tichauer, Kimberley S. Samkoe, Jason R. Gunn, Tayyaba Hasan, Brian W. Pogue. Fluorescent Affibody peptide penetration in glioma margin is superior to full antibody. PLoS ONE 8(4):e60390, 2013
Keith St. Lawrence, Kyle Verdecchia, Jonathan T. Elliott, Kenneth M. Tichauer, Mamadou Diop, Lisa Hoffman, Ting-Yim Lee. Modeling of vascular heterogeneity essential for quantifying tumour physiology by dynamic contrast-enhanced near-infrared monitoring. Physics in Medicine and Biology 58(5):1591-1604, 2013
Kenneth M. Tichauer, Robert W. Holt, Fadi El-Ghussein, Scott C. Davis, Kimberley S. Samkoe, Jason R. Gunn, Frédéric Leblond, Brian W. Pogue. A dual-tracer background subtraction approach for fluorescent molecular tomography studies. Journal of Biomedical Optics 18(1):016003, 2013
2012
Jonathan T. Elliott, Eric A. Wright, Kenneth M. Tichauer, Mamadou Diop, Laura B. Morrison, Brian W. Pogue, Ting-Yim Lee, Keith St. Lawrence. Arterial input function of an optical tracer can be measured from pulse oximetry oxygen saturation measurements. Physics in Medicine and Biology 57(24):8285-8295, 2012.
Kenneth M. Tichauer, Kimberley S. Samkoe, W. Spencer Klubben, Tayyaba Hasan, Brian W. Pogue. Advantages of a dual-tracer model over reference tissue models for binding potential measurement in tumors. Physics in Medicine and Biology 57(20):6647-6659, 2012
Hector R. A. Basevi, Kenneth M. Tichauer, Frédéric Leblond, Brian W. Pogue, Hamid Dehghani, James A. Guggenheim, Robert W. Holt, Iain B. Styles. Compressive sensing based reconstruction in bioluminescence tomography improves image resolution and robustness to noise. Biomedical Optics Express 3(9):2131-41, 2012
Kenneth M. Tichauer, Robert W. Holt, Kimberley S. Samkoe, Fadi El-Ghussein, Michael Jermyn, Jason R. Gunn, Hamid Dehghani, Frédéric Leblond, Brian W. Pogue. Computed tomography-guided time-domain diffuse fluorescence tomography in small animals for localization of cancer biomarkers. Journal of Visualized Experiments Jul 17;(65). pii: 4050, 2012
Robert W. Holt, Kenneth M. Tichauer, Hamid Dehghani, Brian W. Pogue, Frédéric Leblond. Multiple-gate time-domain diffuse fluorescence tomography allows more sparse tissue sampling without compromising image quality. Optics Letters 37(13):2559-61, 2012 [Additionally published in the Virtual Journal of Biomedical Optics, Vol. 7 Iss. 9]
Kenneth M. Tichauer, Kimberley S. Samkoe, Kristian J. Sexton, Jason R. Gunn, Tayyaba Hasan, Brian W. Pogue. Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging. Journal of Biomedical Optics 17(6):066001, 2012
Petra Bonfert-Taylor, Frédéric Leblond, Robert W. Holt, Kenneth M. Tichauer, Brian W. Pogue, Edward C. Taylor. Information loss and reconstruction in highly diffuse optical tomography, Journal of the Optical Society of America A 29(3):321-30, 2012 [Additionally published in the Virtual Journal of Biomedical Optics, Vol. 7 Iss. 5]
Kenneth M. Tichauer, Kimberley S. Samkoe, Kristian J. Sexton, Shannon K. Hextrum, Harold H. Yang, W. Spencer Klubben, Jason R. Gunn, Tayyaba Hasan, Brian W. Pogue. In vivo quantification of tumor receptor binding potential with dual-reporter molecular imaging. Molecular Imaging and Biology 14(5):584-92, 2012
Kimberley S. Samkoe, Kristian J. Sexton, Kenneth M. Tichauer, Shannon K. Hextrum, Omar Pardesi, Scott C. Davis, Julia A. O’Hara, P. Jack Hoopes, Tayyaba Hasan, Brian W. Pogue. High vascular delivery of EGF, but low receptor binding rate is observed in AsPC-1 tumors as compared to normal pancreas. Molecular Imaging and Biology 14(4):472-9, 2012
2011
Qun Zhu, Hamid Dehghani, Kenneth M. Tichauer, Robert W. Holt, Karthik Vishwanath, Frédéric Leblond, Brian W. Pogue. A three dimensional finite element model and image reconstruction algorithm for time-domain fluorescence imaging in highly scattering media. Physics in Medicine and Biology 56:7419-34, 2011
Kenneth M. Tichauer, Robert W. Holt, Fadi El-Ghussein, Qun Zhu, Hamid Dehghani, Frédéric Leblond, Brian W. Pogue. Imaging workflow and calibration for CT-guided time-domain fluorescence tomography. Biomedical Optics Express 2(11):3021-36, 2011
Frédéric Leblond, Kenneth M. Tichauer, Robert W. Holt, Fadi El-Ghussein, Brian W. Pogue. Toward whole-body optical imaging of rats using single-photon counting fluorescence tomography. Optics Letters 36(19):3723-5, 2011 [Additionally highlighted in the Optical Society of America’s Spotlight in Optics, Sep. 2011]
Kenneth M. Tichauer, Mark Migueis, Frédéric Leblond, Jonathan T. Elliott, Mamadou Diop, Keith St. Lawrence, Ting-Yim Lee. Depth resolution and multiexponential lifetime analyses of reflectance-based time-domain fluorescence data. Applied Optics 50(21):3962–72, 2011
Joel A. Cooper, Kenneth M. Tichauer, Melfort Boulton, Mamadou Diop, Miguel Arango, Ting-Yim Lee, Keith St. Lawrence. Continuous monitoring of cerebral blood flow by near-infrared spectroscopy during temporary vessel occlusion. Journal of Applied Physiology 110(6):1691-8, 2011
Matthew J. Murphy, Kenneth M. Tichauer, Louise Sun, Xiagang Chen, Ting-Yim Lee. Evaluation of mean transit time as index of cerebral perfusion pressure in experimentally graded systemic hypotension. Physiological Measurement 32(4):395-405, 2011
Christopher D’Esterre, Kenneth M. Tichauer, Richard I. Aviv, Wolfgang Eisert, Ting-Yim Lee. The effect of dipyridamole on cerebral circulation and stroke outcome in a rabbit model of middle cerebral artery embolic occlusion. Translational Stroke Research 2(2):186-94, 2011
2010
Frédéric Leblond, Kenneth M. Tichauer, Brian W. Pogue. Singular value decomposition metrics show limitations of detector design in diffuse fluorescence tomography. Biomedical Optics Express 1(5):1514-31, 2010.
Mohamadreza Najiminaini, Fartash Vasefi, Kenneth M. Tichauer, Ting-Yim Lee, Bozena Kaminska, Jeffrey J. L. Carson. Angular domain fluorescence lifetime imaging: a tissue-like phantom study. Optics Express 18(22):23247-57, 2010
Mamadou Diop, Kenneth M. Tichauer, Jonathan T. Elliott, Mark Migueis, Ting-Yim Lee, Keith St. Lawrence. Comparison of time-domain and continuous-wave near-infrared spectroscopy techniques of measuring cerebral blood flow in piglets. Journal of Biomedical Optics 15(5):057004, 2010
Kenneth M. Tichauer, Jonathan T. Elliott, Jennifer A. Hadway, David S. Lee, Ting-Yim Lee, Keith St. Lawrence. Using near-infrared spectroscopy to measure the cerebral metabolic rate of oxygen under multiple levels of arterial oxygenation in piglets. Journal of Applied Physiology 109(3):878-85, 2010
Jonathan T. Elliott, Mamadou Diop, Kenneth M. Tichauer, Ting-Yim Lee, Keith St. Lawrence. Quantitative measurement of cerebral blood flow using depth-resolved near-infrared spectroscopy in a juvenile porcine model. Journal of Biomedical Optics 15(3):037014, 2010
2009
Mamadou Diop, Jonathan T. Elliott, Kenneth M. Tichauer, Ting-Yim Lee, Keith St. Lawrence. A broadband continuous-wave multi-channel near infrared system for measuring regional cerebral blood flow and oxygen consumption in newborn piglets. Review of Scientific Instruments 80(5):054302, 2009. [Additionally published in the Virtual Journal of Biological Physics Research, May 15, 2009 edition]
Kenneth M. Tichauer, Jonathan T. Elliott, Jennifer A. Hadway, Ting-Yim Lee, Keith St. Lawrence. Cerebral metabolic rate of oxygen and amplitude-integrated electroencephalography during early reperfusion after hypoxia-ischemia in piglets. Journal of Applied Physiology 106(5):1506-12, 2009
Kenneth M. Tichauer, Daisy YL Wong, Jennifer A Hadway, R Jane Rylett, Ting-Yim Lee, Keith St. Lawrence. Assessing the severity of hypoxia-ischemia using near-infrared spectroscopy to measure the cerebral metabolic rate of oxygen in piglets. Pediatric Research 65(3):301-6, 2009
Jeff D. Winter, Kenneth M. Tichauer, Neil Gelman, R. Terry Thompson, Ting-Yim Lee, Keith St. Lawrence. Changes in cerebral oxygen consumption and high-energy phosphates during early recovery from hypoxia-ischemia: A combined near-infrared and magnetic resonance spectroscopy study. Pediatric Research 65(2):181-7, 2009
2006
Kenneth M. Tichauer, Derek W. Brown, Jennifer Hadway, Ting-Yim Lee, Keith St. Lawrence. Near-infrared spectroscopy measurements of cerebral blood flow and oxygen consumption following hypoxia-ischemia in newborn piglets. Journal of Applied Physiology 100(3):850-7, 2006
Kenneth M. Tichauer, Jennifer Hadway, Ting-Yim Lee, Keith St. Lawrence. Measurement of cerebral oxidative metabolism with near-infrared spectroscopy: a validation study. Journal of Cerebral Blood Flow and Metabolism 26(5):722-30, 2006