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Advanced Lymph Node Biopsy
Advanced Lymph Node Biopsy
Summary
Summary
The lymph system is the predominant route through which cancer spreads for many cancer subtypes. Once cancer has spread from the primary tumor site, surgery is generally no longer “curative.” However, in some cases, it can be if the spread is confined to the nearby lymph nodes, which can be located and removed surgically.
Funding
Funding
NSF CAREER 1653627 (2016-2021), Nayar Prize at Illinois Tech (2015-2018).
Cancer Margin Topography
Cancer Margin Topography
Summary
Summary
Particularly for high morbidity surgeries in older or compromised patients, cancer surgeons need to be sure they have removed as much cancer as possible while the patient is still on the table, since callback surgeries are hard on these patients and come at significant costs to health care systems.
Funding
Funding
NIH R21 CA1215561
Retina Perfusion and Vascular Permeability
Retina Perfusion and Vascular Permeability
Summary
Summary
Among the many complications of diabetes is retinopathy, which is essentially damage to cells in the retina that can lead to loss of vision. Unfortunately, by the time patients realize they are losing vision, the damage is irreparable by current clinical options. Our lab has been developing a method to extract quantitative maps of retinal blood flow and vascular permeability as a potential early indicator of retinopathy before it occurs, when drug intervention could delay or avoid vision loss.
Other Projects
Other Projects
Summary
Summary
Paired-agent fluorescence guided surgery in head and neck cancer
MRI-guided fluorescence tomography to quantify drug efficacy in preclinical models
Intracellular quantitative fluorescence molecular imaging
Ultrasound molecular imaging for in vivo detection of cancer-positive lymph nodes
Molecular and mechanical property imaging to elucidate why cancer drugs fail
Low dose phase-contrast CT for mammography
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