Research

Sponsored Research Projects

Type 1 Diabetes in Premenopausal Women: Integrating Menstrual Cycle Related Physiological Changes and Symptoms into a Multivariable Artificial Pancreas, JDRF ($1,996,209. IIT budget $560,593, 2/20-1/24) IIT subcontract PI, Grant PI: Laurie Quinn – University of Illinois at Chicago. (JDRF had to end the grant as of 8/2020 - IIT budget was $108,000)

An Agent-Based Approach to Modeling Prescribing Behaviors for Diabetes Care Health Care Providers for Underserved Populations, University of Chicago - The Institute for Translational Medicine, ($90,131, 1/19-6/20) co-PI, PI: Eunice Santos, CS, IIT

Gradient Hydrogels to Promote MSC Differentiation for Osteochondral Defect Repair, NIH ($197,675, 1/19-3/20) co-PI, PI: Georgia Papavasiliou, BME, IIT

Big Data Analysis with Statistical, Control Engineering, Machine Learning and Error embedded Deep Neural Networks Techniques for Enhancing Glucose Regulation and AP Algorithms, JDRF, ($190,484, 7/19-6/20)). PI .Co-PI: Keigo Kawaji - IIT

mDGS: A novel mobile dietary guidance system for the management of type 2 diabetes using CGM-based hyperglycemia prediction, Subcontract from Viocare, Inc. (Primary funding source SBIR NIH), ($ 57,364 (IIT budget), 5/19-4/20). PI

NIPTE Training and Certification Program in Pharmaceutical Technology, Subcontract from the National Institute of Pharmaceutical Research and Education (Primary Funding Agency: US FDA), ($47,913, 9/18-10/19). PI. Co-PI: Seok-Hoon Hong - IIT

Additional Signals for Detection of Exercise, Stress and Sleep Effects and Prediction of Glucose Levels for Next Generation AP Systems, Juvenile Diabetes Research Foundation (JDRF), ($530,000, 8/17-1/20). PI. Co-PI: Laurie Quinn – University of Illinois at Chicago.

Agent-based Modeling of Fed-Batch Cell Culture Bioreactor, Amgen, ($120,000, 11/15-11/19). PI

Development of NIPTE Industrial Training Program, National Institute for Pharmaceutical Technology and Education (NIPTE), ($44,900, 12/16-11/17). PI

MD-PSYCH Models, signals, and distributed bio-behavioral control of exercise in diabetes, National Institutes of Health (NIH) ($2.98 million total, IIT Subcontract: $440,211, 8/15-7/19) PI: M. Breton, University of Virginia, IIT-PI: A. Cinar

Collection and Analysis of Multivariable Data in Diabetes Sports Camps, Juvenile Diabetes Research Foundation (JDRF) ($109,916, 9/15-8/16) PI. Co-PIs: Laurie Quinn – University of Illinois at Chicago, Monica Joyce - Diabetes Education Program.

Artificial pancreas for use during and after exercise, National Institutes of Health (NIH) ($2.48 million, 9/13-6/18) PI, Co-PIs: Elizabeth Littlejohn – University of Chicago, Lisa Sharp and Laurie Quinn – University of Illinois at Chicago, Michael Riddell – York University.

Fault Detection, Diagnosis and Recovery for Risk Mitigation in AP Systems, Juvenile Diabetes Research Foundation (JDRF) ($592,000, 8/13-7/15) PI, Co-PIs: Elizabeth Littlejohn – University of Chicago, and Laurie Quinn – University of Illinois at Chicago.

Fault-Tolerant Artificial Pancreas, NIH ($1.97 million, 9/13-6/18) PI, Co-PIs: Elizabeth Littlejohn – University of Chicago, Lisa Sharp and Laurie Quinn – University of Illinois at Chicago.

CDI-Type II: Optimization of Engineered Tissue Growth by Active Learning, NSF ($1.34 million, 10/11-9/17), PI, Co-PIs: M. Bilgic, E. Brey, M. North, J. Zawojewski

Multivariable Closed-Loop Technologies for Physically Active Young Adults with Type 1 Diabetes, NIH-NIDDK ($450,500, 9/09 – 8/13, PI, Co-PIs: L. Quinn, E. Littlejohn, D. Rollins)

Subject-Specific Glucose Prediction Models and Automatic Adaptive Control Systems for an Artificial Pancreas, Pilot and Feasibility Study, University of Chicago (NIDDK/NIH-Sponsored Diabetes Research and Training Center) (2/09 – 1/11, PI, co-PIs: L. Quinn, D. Rollins, E. Littlejohn)

Multivariate Statistical Analysis of Process Data, Corning, Inc. (9/07 – 12/08), PI.

Stochastic Agent-based Modeling of Angiogenesis and Tissue Growth, NSF ($270,000, 9/07-8/12, PI. Co-PIs: E. Brey and J. Duan)

IIT Research Experiences for Teachers (RET) Site – Corps of Educators and Workshop, NSF (5/05 – 4/09, Co-PI, A. Flueck, PI)

ITR – Agent-Based Systems for Monitoring, Analysis, Diagnosis and Control, NSF ($1.95 million, 9/03 – 8/10, PI. co-PIs: C. Hood, F. Teymour)

Methods and Tools for Modeling and Analysis of Metabolic Processes, IITRI Research Grant Program

IIT Research Experiences for Teachers (RET) Site – Corps of Educators and Workshop, NSF

Real Time Multivariable Statistical Monitoring of Batch Pharmaceutical Processes, NSF-GOALI

Research Experiences for Teachers (RET) Workshop: Linking Teachers to Research Experiences Program, NSF

Virtual Experiments for Biomedical Engineering Education, NSF

Quality, Safety Monitoring and Fault Diagnosis in Multivariable Food Processing, USDA

Control System Performance Assessment, Equilon Company

Statistical Methods and Mathematical Modeling for On-line Monitoring of Critical Control Points for Food Processes, FDA/National Center for Food Safety and Technology (NCFST)

Assessment of Professional Ethics Education and Integration of Product Quality, Safety, and Professional Ethics (M. Davis, Co-PI), Center for Innovative Learning and Education

Modeling and Control of Multivariable Refining Processes, Amoco Oil Company

Statistical Monitoring of Multivariable Continuous Processes, Amoco Chemical Company

An Integrated Process Monitoring and Control System for Multivariable Processes in Advanced Materials Manufacturing, American Statistical Association / National Science Foundation / National Institute of Standards and Technology, (8/92 - 8/93) Senior and Associate Research Fellowship

Automated Control of Thermal Food Processing: HTST Prototype Demonstration, FDA/ National Center for Food Safety and Technology (NCFST)

Hewlett Packard Equipment Grant for Studies in Process Monitoring and Control, Hewlett-Packard Company

Expert Control Systems for Supervisory Control of Chemical Process Plants, State of Illinois - IIT Technology Commercialization Center

Fault-Tolerant Expert Controllers for Chemical Reactor Systems, Johnson's Wax Fund

Development of Artificial Intelligence Tools for Real-Time Expert Control Systems, IIT/IITRI Operation Synergy

Studies in Real-Time Expert Systems, IIT Education and Research Initiative Fund

Studies in Selectivity and Yield Improvement in Chemical Reactors by Periodic Operation, American Chemical Society - Petroleum Research Fund

Vibrational Control of Chemical Reactors: Selectivity Enhancement, Stabilization and Improvement of Transient Behavior, Department of Energy

Selectivity and Yield Increase in Ethylene Oxidation by Periodic Operation. State of Illinois - IIT Technology Commercialization Center

Model-Based Expert Control Systems, (P. Greene, Co-PI) Illinois Institute of Technology Galvin Venture Fund

Industrial Waste Elimination by Periodic Operation, EPA - Industrial Waste Elimination Research Center

Vibrational Control in Stabilization of Chemical Reactors, (S.M. Meerkov Co-PI during the first project term 3/84-9/84) Department of Energy

Modeling and Control of Energy Integrated Reactor Systems, American Chemical Society - Petroleum Research Fund