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Research Areas
Research Areas
My research activities are concentrated in three areas: modeling, simulation and control of biomedical systems, complex adaptive agent-based systems, and supervision of process operations. The research activities focus on the development of theory, methods, and tools to use in various application areas.
Modeling, simulation and control of biomedical systems
Modeling, simulation and control of biomedical systems
Supported by National Institutes of Health – NIH and Juvenile Diabetes Research Foundation - JDRF
Multivariable artificial pancreas systems for people with diabetes
Simulation systems for glucose, insulin and physiological variable dynamics in Type 1 and Type 2 diabetes
Development of an agent-based model to simulate the destruction of insulin producing beta cells in the pancreas by the immune system and the onset of diabetes
Artificial Pancreas
Complex adaptive agent-based systems
Complex adaptive agent-based systems
Supported by NSF and industry
Hierarchical multi-agent systems for modeling, supervision, and control of distributed complex systems
Agent-based modeling of mammalian cell bioreactors used in biopharmaceutical manufacturing
Simulation visualization for 2-week vascularization (red) and tissue growth (pink)
Disturbance rejection by programmed cell death (infection at center reactor)
Supervision of process operations
Supervision of process operations
(Supported by NSF, NIH, JDRF, and industry
Multivariable process monitoring, performance assessment, and fault diagnosis
Knowledge-based systems for supervisory process control and intelligent process operations
Process monitoring, supervision and control with agent-based systems
Sponsored research projects
Sponsored research projects
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