Evidence-based medicine, coined in 1992 by Gordon Guyatt of McMaster University, has also be called 'enlightened skepticism.'  Listen to these inspirational stories of EBM: the past, present and future: An oral history.

https://files.jamanetwork.com/sdebm/

Granular components of EBM:

• Scientific skepticism

• Critical analysis of literature

• Constant reappraisal of the evidence/literature

Combined with:

• Clinical experience --> clinical expertise via deliberate practice (planning, performing, reflecting)

• Patient values and preferences

• Clinical context of a given patient, physicians & system at a given moment in time

Beware of clinical inertia and evidence-based exit block where clinical practice has failed to become fully aligned with strong evidence supporting a change in diagnosis or therapy.  

-Goldberger LA and Goldberger ZD.  Becoming a Consummate Clinician: What Every Student, House Officer, and Hospital Practitioner Needs to Know. Wiley-Blackwell: 2012.