2019

MAPK Erk5 in Leptin Receptor‒Expressing Neurons Controls Body Weight and Systemic Energy Homeostasis in Female Mice.

Horie T., Park G., Inaba Y., Hashiuchi E., Iezaki T., Tokumura K., Fukasawa K., Yamada T., Hiraiwa M., Kitaguchi Y., Kamada H., Kaneda K., Tanaka T., Inoue H., and Hinoi E#.

Endocrinology 160(12):2837-2848. 2019.

•  DOI: 10.1210/en.2019-00090

Endocrine news（Trends and Insights）に掲載 

Inhibition of the glutamine transporter SNAT1 confers neuroprotection in mice by modulating the mTOR-autophagy system.

Yamada D., Kawabe K., Tosa I., Tsukamoto S., Nakazato R., Kou M., Fujikawa K., Nakamura S., Ono M., Oohashi T., Kaneko M., Go S., Hinoi E., Yoneda Y, and  Takarada T.

Commun. Biol. 2(1):346. 2019.

•  DOI: 10.1038/s42003-019-0582-4

Acute Cocaine Reduces Excitatory Synaptic Transmission in Pyramidal Neurons of the Mouse Medial Prefrontal Cortex.

Sasase H., Izumi S., Deyama S., Hinoi E., and  Kaneda K.

Biol. Pharm. Bull. 42(8):1433-1436. 2019.

•  DOI: 10.1248/bpb.b19-00318

Postnatal Runx2 deletion leads to low bone mass and adipocyte accumulation in mice bone tissues.

Tosa I., Yamada D., Yasumatsu M., Hinoi E., Ono M., Oohashi T., Kuboki T., and Takarada T.

Biochem. Biophys. Res. Commun. 516(4):1229-1233. 2019.

•  DOI: 10.1016/j.bbrc.2019.07.014

The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway.

Ozaki K., Yamada T., Horie T., Ishizaki A., Hiraiwa M., Iezaki T., Park G., Fukasawa K., Kamada H., Tokumura K., Motono M., Kaneda K., Ogawa K., Ochi H., Sato S., Kobayashi Y., Shi YB., Taylor PM., and Hinoi E#.

Sci. Signal. 12(589):eaaw3921. 2019. 

•  DOI: 10.1126/scisignal.aaw3921

プレスリリース　F1000Primeに選出　雑誌表紙に採用　AMED・HPに掲載　シグナリングに載った日本人研究者に掲載 

Daily intake of polyamine-rich Saccharomyces cerevisiae S631 prevents osteoclastic activation and bone loss in ovariectomized mice.

Yamada T., Park G., Node J., Ozaki K., Hiraiwa M., Kitaguchi Y., Kaneda K., Hiramoto S., and  Hinoi E#.

Food Sci. Biotechnol. 28:1241-1245. 2019.

•  DOI: 10.1007/s10068-019-00561-4

Telemetered common marmosets is useful for the assessment of electrocardiogram parameters changes induced by multiple cardiac ion channel inhibitors.

Watanabe K., Tsubouchi T., Yamada T., Hinoi E., and Miyawaki I.

J. Toxicol. Sci. 44(7):441-457. 2019.

•  DOI: 10.2131/jts.44.441

mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis.

Hiraiwa M., Ozaki K., Yamada T., Iezaki T., Park G., Fukasawa K., Horie T., Kamada H., Tokumura K., Motono M., Kaneda K., and Hinoi E#.

Front. Pharmacol.10:684. 2019.

•  DOI: 10.3389/fphar.2019.00684

Effects of the synthetic cannabinoid 5F-AMB on anxiety and recognition memory in mice.

Ito S., Deyama S., Domoto M., Zhang T., Sasase H., Fukao A., Esaki H., Hinoi E., Kaneko S., and Kaneda K.

Psychopharmacology 236:2235-2242. 2019.

•  DOI: 10.1007/s00213-019-05222-2

Hypoxia affects Slc7a5 expression through HIF-2α in differentiated neuronal cells.

Onishi Y., Hiraiwa M., Kamada H., Iezaki T., Yamada T., Kaneda K., and Hinoi E#.

FEBS Open Bio 9(2):241-247. 2019.

•  DOI: 10.1002/2211-5463.12559

Cartilage Induction from Mouse Mesenchymal Stem Cells in High-density Micromass Culture. 

Iezaki T., Fukasawa K., Yamada T., Hiraiwa M., Kaneda K., and Hinoi E#. 

Bio Protoc. 2019. 9(1):e3133. 

•  DOI: 10.21769/BioProtoc.3133