To achieve greater reliability and more accurate results in esophageal motility testing, a standardized conductivity of 8.55 ± 0.5 ms/cm was targeted. The standardization of conductivity allows doctors and researchers to more accurately compare the results of tests.
Removing air from the medium is necessary to prevent air bubbles from interfering in ultrasound images and changing conductivity readings. Degassing was attempted by mechanical and chemical means. A vacuum chamber was used to try degassing several jars of viscous gel, which proved to be ineffective. A chemical degassing agent and high processing temperature were found to be most effective.
High viscosity is helpful to achieve greater resistance to air when the gel is swallowed. This was accomplished by using a gelling agent to thicken the solution, and a viscometer was used to ensure that the production procedure resulted in a standardized viscosity.
Because the strong, unpleasant taste of saline is known to cause some patients to regurgitate during testing, flavoring was added to the new challenge medium to help conceal the taste of salty electrolytes. A lemon flavoring was chosen for its ability to effectively cover the taste of salt while also being economically viable, as opposed to children's medicinal flavoring.
The packaging was chosen in accordance to the degree of ease that nurses performing the testing procedure would experience. Tall containers were found to allow the tester to more easily draw the last deposition with a syringe. Ribbed lids were selected for better grip and ease of opening. Liners between the lid and container were fitted to reduce spillage and make the container more airtight. Finally, shrink wrap around the lid was added to make the container tamper-evident.
The containers are packaged into a cardboard box with spacers to reduce the amount of shaking they would experience during shipping so less air bubbles would be introduced into the gel.