Visualize T-cells Using Magnetic Resonance Imaging via a MRI Reporter Gene
BENG 187 Senior Design Group 35: Mitchell Kong, Yuzhou Tong, and Yingxiao Wang (Mentor)
We need to develop an imaging-based detection method for cancers which can determine whether programmed T-cells have successfully recognized tumor antigens in vivo.
References:
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Bourre, L. “How to Assess CAR-T Cell Therapies Preclinically.” February 20, 2018
Kim, H.S.; Woo, J.; Choi, Y.; Hwang, E.H.; Choi, S.K.; Cho, K.W.; Moon, W.K. Noninvasive MRI and multilineage differentiation capability of ferritin-transduced human mesenchymal stem cells. NMR Biomed. 2015, 28, 168–179