研究成果
講演
中野賢 ``バイオとICTを融合する分子通信研究,'' 未来ICTシンポジウム 2025, nano tech 2025, Feb. 2025.
T. Nakano, ``Collective Migration and Large-scale Structure Formation of Cancer Cells," Workshop on Molecular, Biological, and Multi-Scale Communications (WMBMC), Virtual, Jan. 2023.
中野賢 ``生体内分子通信ネットワークの理解と医療応用,'' 未来の医療・ライフサイエンスを支えるスマートケミストリー、日本化学会第102春季年会, March 2022.
中野賢、``がん細胞集団が作る大規模ネットワーク構造の分析,'' BioMedical Forum 2022, Jan. 2022.
学術論文誌掲載論文
M. Nishino and T. Nakano, ``The Pulse Timer Algorithm for Mobile Molecular Communication,'' IEEE Communications Letters, vo. 29, no. 9, pp. 1196-1199, June 2025.
T. Saiki, S. Imanaka, S. Kobayashi, T. Nakano, ``A General-Purpose Simulation Platform for Multicellular Molecular Communication Systems,'' IEEE Transactions on Molecular, Biological, and Multi-Scale Communications, vol. 11, no. 2, pp. 152-165, June 2025.
M. Chiba and T. Nakano, ``Performance Analysis of a Biologically Inspired Collective Gradient Detection Method for a Bio-nanomachine Cluster,'' IEEE Communications Letters, vol. 28, no. 11, pp. 2528-2532, Sept. 2024.
J. Wang and T. Nakano, ``Modelling and Simulations of Collective Bio-nanomachine Rotation in Three-dimensional Space," IEEE Transactions on Molecular, Biological and Multiscale Communications, vol. 9, no. 2, pp. 222-226, June 2023.
J. Wang and T. Nakano, ``A Biologically Inspired Model of Collective Bio-nanomachine Rotation via Chemical and Physical Interactions,'' IEEE Transactions on NanoBiosciences, vol. 22, no. 3 , pp. 570-581, 2022.
H. Hiraoka, J. Wang, T. Nakano, Y. Hirano, S. Yamazaki, Y. Hiraoka, T. Haraguchi, ``ATP levels influence cell movement during the mound phase in Dictyostelium discoideum as revealed by ATP visualization and simulation,'' FEBS Open Bio, no. 12, vol. 11, pp. 2042-2056, Aug. 2022.
Y. Cevallos, T. Nakano, L. Tello-Oquendo, A. Rush, D. Inca, I. Santillán, A. Z. Shirazi, and N. Samaniego, ``A Brief Review on DNA Storage, Compression, and Digitalization,'' Nano Communication Networks, vol. 31, 100391, March 2022.
Y. Cevallos, T. Nakano, L. Tello-Oquendo, D. Inca, I. Santillan, A. Zadeh Shirazi, A. Rushdi and N. Samaniego, ``Modeling Gene Expression and Protein Delivery as an End-to-End Digital Communication System," The Open Bioinformatics Journal, vol. 14, pp. 21-35, Feb. 2021.
A. D. Odysseos and T. Nakano, ``Bionanomachine Diagnostics and Nanonetwork Therapeutic in Brain Malignanices with Bionanodevice Interfaces,'' IEEE Transactions on Molecular, Biological and Multiscale Communications, May 2021.
Y. Okaie and T. Nakano, ``Mobile Molecular Communication through Multiple Measurements of the Concentration of Molecules,'' IEEE ACCESS, vol. 8, pp. 179606−179615, Sept. 2020.
Z. He, C. Yao, J. Shuai and T. Nakano, ``Enhanced Vibrational Resonance in a Single Neuron with Chemical Autapse for Signal Detection,'' Chinese Physics B, vol 29, no. 12, Nov. 2020.
H. Hiraoka, T. Nakano, S. Kuwana, M. Fukuzawa, Y. Hirano, M. Ueda, T. Haraguchi, and Y. Hiraoka, ``Intracellular ATP Levels Influence Cell Fates in Dictyostelium Discoideum Differentiation,'' Genes to Cells, vol. 25, no. 5, 312−326, March 2020.
T. Nakano, Y. Okaie, Y. Kinugasa, T. Koujin, T. Suda , Y. Hiraoka, and T. Haraguchi, ``Roles of Remote and Contact Forces in Epithelial Cell Structure Formation,'' Biophysical Journal, vol. 118, issue 6, 1466−1478, March 2020.
T. Nakano, L. Lin, Y. Okaie, C. Wu, H. Yan, T. Hara, and K. Harumoto, ``Random Cell Motion Enhances the Capacity of Cell-cell Communication,'' IEEE Transactions on Molecular, Biological and Multiscale Communications, vol. 5, issue. 2, 158−162, Nov. 2019.
T. Nakano, Y. Okaie, S. Kobayashi, T. Hara, Y. Hiraoka, and T. Haraguchi, ``Methods and Applications of Mobile Molecular Communication,'' Proceedings of the IEEE, vol. 107, no. 7, pp. 1442--1456, July 2019.
C. Yao, Z. He, T. Nakano, Y. Qian, and J. Shuai, ``Inhibitory-autapse-enhanced Signal Transmission in Neural Networks,'' Nonlinear Dynamics, vol. 97, no. 2, pp. 1425−1437, July 2019.
国際会議論文
J. Suzuki, Y. Ch. Ren, and T. Nakano, ``Multiobjective Optimization for Feedback-based, Multi-hop Molecular Communication,'' 18th IIAI International Conference on Advanced Applied Informatics (IIAI AAI 2025), 7 pages, Kokura, 2025.
S. Kotani, T. Nakano, and C. Yokoyama, ``In Vitro Experiments and Computational Modeling of Cancer Invasion,'' 2024 Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems (SCIS&ISIS), 5 pages, Himeji, 2024.
R. Hosono, T. Nakano, Y.-H. Hsu and W. C. Tang, ``Modelling Mechanical Communication and Collective Motion of Cancer Cells,'' 2024 Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems (SCIS&ISIS), 5 pages, Himeji, 2024.
S. Imanaka and T. Nakano, ``Algorithm Design for Multicellular Molecular Communication Simulations,'' 7th International Conference on Knowledge Innovation and Invention 2024 (ICKII 2024), Aichi, Aug. 2024.
T. Nakano, R. Hosono, Y.-H. Hsu, and W. C. Tang, ``Cell-cell communication through deformation of extracellular matrix,'' 2024 IEEE 6th Eurasia Conference on Biomedical Engineering, Healthcare and Sustainability (ECBIOS), Taiwan, June 2024.
R. Tada, T. Nakano and T. Suda, ``Modelling Cell Cluster Growth Using the Cellular Potts Model,'' 2024 IEEE 4th International Conference on Electronic Communications,Internet of Things and Big Data (ICIEB 2024), Taiwan, April 2024.
T. Yamakawa, T. Nakano and T. Suda, ``Dynamic Cluster Formation Through Molecular Communication Among Bio-nanomachines,'' 2024 IEEE 4th International Conference on Electronic Communications,Internet of Things and Big Data (ICIEB 2024), Taiwan, April 2024.
S. Imanaka, T. Saiki and T. Nakano, ``Accelerating Multicellular Molecular Communication Simulations Using the Barnes-Hut Algorithm,'' 2024 IEEE 4th International Conference on Electronic Communications,Internet of Things and Big Data (ICIEB 2024), Taiwan, April 2024.
T. Nakano and T. Suda, ``Cell Clusters and Their Networks for Emerging Applications,'' in Proc. 7th EAI International Conference on Smart Grid and Internet of Things (EAI SGIoT 2023), Taiwan, Nov. 2023. （Best Paper Award 受賞）
M. Nishino and T. Nakano, ``Modeling and Simulation of a Mobile Molecular Communication System with Frequency-based Directional Sensing,'' in Proc. 2023 IEEE 5th Eurasia Conference on IoT, Communication and Engineering (IEEE ECICE 2023), 4 pages, Taiwan, Oct. 2023.（Best Paper Award 受賞）
J. Wang and T. Nakano, ``Collective Rotational Motion of Bio-nanomachines via Chemical and Physical Interactions,'' in Proc. 2022 IEEE Global Communications Conference (IEEE GLOBECOM 2022), 6 pages, in-person (Brazil) and virtual, Dec. 2022.
K. Matsushita and T. Nakano, ``Wet-laboratory Experiments and Computer Simulation of Growing Cell Clusters," in Proc. 2022 IEEE Global Communications Conference (IEEE GLOBECOM 2022), 6 pages, in-person (Brazil) and virtual, Dec. 2022.
J. Wang and T. Nakano, ``Collective Rotational Motion of Bio-nanomachines in Noisy Environments," full paper, in Proc. 2022 Joint 12th International Conference on Soft Computing and Intelligent Systems and 23rd International Symposium on Advanced Intelligent Systems (SCIS&ISIS 2022), Mie, Nov.--Dec. 2022. （Best Student Presentation Award 受賞）
T. Tsuchiya, T. Nakano and W. Tang, ``Two Point Correlation Analysis of Cancer Cell Structure Formation," full paper, in Proc. 2022 Joint 12th International Conference on Soft Computing and Intelligent Systems and 23rd International Symposium on Advanced Intelligent Systems (SCIS&ISIS 2022), Mie, Nov.--Dec. 2022.
T. Saiki and T. Nakano, ``Design and Implementation of a Multicellular Molecular Communication Simulator," full paper, in Proc. 2022 Joint 12th International Conference on Soft Computing and Intelligent Systems and 23rd International Symposium on Advanced Intelligent Systems (SCIS&ISIS 2022), Mie, Nov.--Dec. 2022.
M. Chiba and T. Nakano, ``Collective Gradient Detection for Forming a Bio-nanomachine Supercluster," short paper, in Proc. 2022 Joint 12th International Conference on Soft Computing and Intelligent Systems and 23rd International Symposium on Advanced Intelligent Systems (SCIS&ISIS 2022), Mie, Nov.--Dec. 2022.
M. Nishino and T. Nakano, ``Frequency-based Directional Sensing for Mobile Molecular Communication," short paper, in Proc. 2022 Joint 12th International Conference on Soft Computing and Intelligent Systems and 23rd International Symposium on Advanced Intelligent Systems (SCIS&ISIS 2022), Mie, Nov.--Dec. 2022.
T. Tsuchiya, T. Saiki, T. Nakano, ``Modeling and Simulations of Vascular-Like Structure Formation of Cancer Cells,'' in Proc. 16th IEEE International Symposium on Medical Information and Communication Technology (ISMICT 2022), 5 pages, Virtual, May 2022.
Y. Cevallos, T. Nakano, L. Tello-Oquendo, N. Chopra, A. Zadeh Shirazi, D. Inca, and Ivone Santillan, ``Theoretical Basis for Gene Expression Modeling Based on the IEEE 1906.1 Standard," in Proc. 13th EAI International Conference on Bio-inspired Information and Communications Technologies (BICT 2021), Virtual, Sept. 2021.
T. Nakano, Y. Okaie, N. Dietis and A. D. Odysseos, ``Growing Bio-nanomachine Networks: Application to Malignant Tumor Evolution and Progression,'' in Proc. 2020 IEEE Global Communications Conference (IEEE GLOBECOM 2020), 6 pages, Taiwan, Dec. 2020. （Best Paper Award 受賞）
T. Nakano and T. Suda, ``Communication, Migration and Energy in Bio-nanomachine Functionality Differentiation,'' in Proc. 2020 IEEE Global Communications Conference (IEEE GLOBECOM 2020), ７pages, Taiwan, Dec. 2020.
S. Ishiyama, T. Nakano, Y. Okaie, T. Hara, and K. Harumoto, ``Cooperative Signaling and Directed Migration of Bio-nanomachines in Mobile Molecular Communication,'' in Proc. 7th ACM International Conference on Nanoscale Computing and Communication (ACM NANOCOM 2020), 7 pages, USA, Sept. 2020.
Y. Okaie and T. Nakano, ``Binary Concentration Shift Keying with Multiple Measurements of Molecule Concentration in Mobile Molecular Communication,'' in Proc. 12th EAI International Conference on Bio-inspired Information and Communications Technologies (BICT 2020), 10 pages, online, July 2020.
K. Yonekura, T. Nakano, Y. Okaie, T. Hara, and K. Harumoto, ``Network Formation Model of Bio-nanomachines Based on Directed Migration and Adhesion,'' in Proc. IEEE Wireless Communications and Networking Conference (IEEE WCNC 2020), 6 pages, South Korea, May 2020.
P. He, T. Nakano, D. Wu, B. Yang, H. Liu, and X. Han, ``Calcium Signaling in Mobile Molecular Communication Networks,'' in Proc. 2019 IEEE Global Communications Conference (IEEE GLOBECOM 2019), 6 pages, USA, Dec. 2019.
T. Suda and T. Nakano, ``Modeling the Stochastic Behavior of Kinesin-Coated Beads,'' in Proc. 2019 IEEE International Conference on Communications (IEEE ICC 2019), 7 pages, China, May 2019.
口頭発表
M. Chiba and T. Nakano, ``Simulating Multi-target Detection by a Molecular Communication System with Cooperative Gradient Detection,'' 2024 Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems (SCIS&ISIS), extended abstract, Himeji, 2024.
X. Wang and T. Nakano, ``Void-Based Analysis of Vascular-Like Networks,'' 2024 Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems (SCIS&ISIS), extended abstract, Himeji, 2024.
J. Zhu and T. Nakano, ``Simulating Multi-target Detection by a Molecular Communication System with Cooperative Gradient Detection,'' 2024 Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems (SCIS&ISIS), extended abstract, Himeji, 2024.
T. Saiki and T. Nakano, ``A Simulation Platform for Dynamic Multicellular Molecular Communication Systems,'' 2024 IEEE 4th International Conference on Electronic Communications,Internet of Things and Big Data (ICIEB 2024), Taiwan, April 2024.
T. Nakano and W. C. Tang, ``Modelling and Computer Simulation of Large-scale Network Formation of Cancer Cells,'' 2023 IEEE 5th Eurasia Conference on IoT, Communication and Engineering (IEEE ECICE 2023), Taiwan, Oct. 2023.
今中将平, 済木啓雅, 中野賢, ``Barnes-Hutアルゴリズムによる分子通信シ ミュレーションの高速化,'' 2023年電子情報通信学会ソサイエティ大会, Sept. 2023.
山川智矢, 中野賢, ``分子通信を介したバイオナノマシンによる集合体 の動的形成システム,'' 2023年電子情報通信学会ソサイエティ大会, Sept. 2023.
多田澪, 中野賢, ``Cellular Potts Modelを用いた成長する細胞塊の コンピュータシミュレーション,'' 2023年電子情報通信学会ソサイエティ大会, Sept. 2023.
J. Wang and T. Nakano, ``An Agent-based Modelling Approach to Molecular Communication and Multicellular Structure Formation,'' The 2023 Conference on Artificial Life (ALIFE 2023), Satellite Workshop on Molecular Communication Approaches for Wetware Artificial Life, Sapporo, July 2023.
J. Wang and T. Nakano, ``Collective Bio-nanomachine Rotation via Chemical and Physical Interactions: A Three- dimensional Model, '' 14th EAI International Conference on Bio-inspired Information and Communications Technologies (BICT 2023), Okinawa, April 2023.
K. Matsushita, T. Nakano, K. Takako and S. Kobayashi, ``Wet-laboratory Experiments and Computer Simulation of Interacting Cell Spheroids,'' 14th EAI International Conference on Bio-inspired Information and Communications Technologies (BICT 2023), Okinawa, April 2023.
S. Takanori and T. Nakano, ``Design and Implementation of a General-purpose Multicellular Molecular Communication Simulator,'' 14th EAI International Conference on Bio-inspired Information and Communications Technologies (BICT 2023), Okinawa, April 2023.
千葉 万柚香, 中野 賢, ``バイオナノマシン集団による分子通信を介した信号分子濃度の協調検出方式," 第21回情報科学技術フォーラム（FIT2022）, Sept. 2022.
王 潔文、中野 賢、``分子通信を介して相互作用するバイオナノマシンの集団回転運動," 第21回情報科学技術フォーラム（FIT2022）, Sept. 2022.
Y. Hiraoka, T. Nakano, T. Haraguchi, Y. Hiraoka, ``The Role of Moving Cells in Fruiting Body Formation Revealed by ATP Visualization and Simulation in Dictyostelium Discoideum,'' 第44回日本分子生物学会年会, Nov. 2021.
平岡陽花, 中野賢, 原口徳子, 平岡泰, ``細胞性粘菌の柄細胞分化を決定する高ATP濃度はマウンド細胞塊中心部への細胞移動を促進する,'' 第12回 日本細胞性粘菌学会例会, Oct. 2021.
ポスター発表
T. Nakano, T. Haraguchi, and Y. Hiraoka, ''Roles of Remote and Contact Forces in Multicellular Structure Formation during HeLa Cell Migration,'' 第77回日本細胞生物学会・第58回日本発生生物学会合同大会, Jul. 2025.
細野亮介、中野賢、Yu-Hsiang Hsu, William C. Tang, ''場を介した細胞間のコミュニケーションとモデル化,'' BioMedical Forum 2025, Dec. 2024.
小谷真士、中野賢、横山智哉子、''がん細胞スフェロイドの浸潤実験とコンピュータシミュレーションによる分析,'' BioMedical Forum 2025, Dec. 2024.
土屋友佳、中野賢、William C. Tang, ``２点相関関数を用いたがん細胞の空間構造解析,'' BioMedical Forum 2024, Dec. 2023.
土屋友佳、中野賢、``がん細胞集団による構造形成の個体ベースモデルとコンピュータシミュレーション,'' BioMedical Forum 2022, Jan. 2022.
分子通信関連以外の論文や2018年以前に発表した論文の情報については、以下をご覧ください。