Data
Contributing Data to the PGC:
The PGC has recently developed a protocol and online system to welcome new PGC collaborators and streamline the entry of new data into the PGC. Please visit the Join the PGC section of the PGC's main web page to learn more about this process.
Data of Interest
ADHD diagnosis and microarray genome-wide data
Dimensional data (symptom rating scales)
Cognitive phenotypes (e.g., working memory, response inhibition, neuropsychological tests)
Copy number variation (CNV) data
Accessing PGC Data:
The PGC has a clear workflow for secondary use proposal vetting and data access. Please visit the Data Access page for an overview of this process and the How to Request Data Access page for more details.
Active Approved Secondary Proposals using PGC-ADHD data:
Title: Stratified familial polygenic transmission in ADHD.
Investigators: Daniel Weiner et al.
Title: Genetic influences on age of onset of ADHD.
Investigators: Cathryn Lewis, Steve Faraone, Philip Asherson, Jessica Agnew-Blais
Title: PGC Primary CNV Analysis
Investigators: Jonathan Sebat et al.
Title: Do polygenic risk scores predict persistence and remission of ADHD in young adulthood?
Investigators: Nicoletta Adamo, Paul O’Reilly, Celeste Cheung, Barbara Franke, Stephen Faraone, Philip Asherson, Claiton Bau, Tetyana Zayats, Soren Dalsgaard, Psychiatric Genomics Consortium ADHD Working Group, Jan Buitelaar, Jonna Kuntsi
Title: Identification of genetic variants associated with resilience to psychiatric disorders among individuals at high genetic risk.
Investigators: Stephen J. Glatt, Stephen V. Faraone, Daniel S. Tylee, Jonathan L. Hess, Susan L. Santangelo, James B. Potash, Tiffany A. Greenwood, Manuel Mattheisen, Klaus-Peter Lesch, Edmund Sonuga-Barke, Caroline Nievergelt, John Kelsoe, Howard Edenburg, Peter Holmans, Mike Neale
Title: Pathway-based genetic risk prediction of psychopathology relevant to reward system dysfunction
Investigators: Eric Barnett et al
Title: Genetics of Response Inhibition in community and clinical samples
Investigators: Christie Burton, Mathieu Lemire, Mark Bellgrove, Russell Schachar, Paul Arnold, Jennifer Crosbie
Title: Exploration of impact of alternate genotypic models on PRS with particular interest in mixed populations
Investigators: Chris Laughlin, Erika Nurmi, et al.
Title: Parent of Origin Effects in ADHD
Investigators: Elizabeth Corfield, Dinka Smajlagić, Siobhan Connoly, Alexandra Hadval, Martin Tesli, Hakon Hakonarson, Irwin Waldman, Josephine Elia, Elisabeth Heron, Ted Reichborn-Kjennerud, Jan Haavik, Stefan Johansson, Tetyana Zayats