‘Arrows in the quiver’: interdisciplinary team contributes to statewide COVID-19 modeling task force (5/20)
“Before expert modeling groups like the Institute for Health Metrics and Evaluation came out with models, we needed to be able to come up with something fast and useful,” said Ferguson.
Physics faculty and colleagues discover window into the human genome (12/19)
“Nobody has ever measured the timing between the binding of a molecule, called a transcription factor, to a gene and then the resulting transcription of the RNA, so we’re the only ones that have ever made that measurement. What it can do is open a window into the living genome, as a dynamic living thing,” said assistant professor Matt Ferguson.
Advanced imaging technology reveals pulsed hormone release regulates gene transcription (9/19)
"Earlier technologies had allowed researchers to average transcription factor dwell times over the entire genome and infer what happened at individual genes. However, using a novel imaging technique called 3D orbital tracking (3DOT) Hager’s team correlated bursting at a specific gene, as well as the proteins involved in transcription arriving at the gene. “This has been a holy grail in the field for many years now,” Hager says."
Boise State Biophysicist Awarded NIH Grant to Study How the Genome Works (8/17)
"Matt Ferguson was awarded a three-year, $410,000 award to study and help explain the basic functions of the human genome."
Ph.D. in Biomolecular Sciences (10/16)
"Biophysicist Dr. Matt Ferguson and molecular and cellular biologist Dr. Eric Hayden have teamed up to investigate a synthetic approach to gene regulation."
Boise State Physicist Extracts Lessons from Sea Squirts (7/16)
"Now, a newly formed research team, financed by an innovative Scialog Award, will attempt to discover at least a few mechanical modules by focusing on a specific system of broad interest — cell extrusion in epithelial sheets."
When Timing Matters (10/15)
“Our studies on the mutant U2AF1 suggest a role for mutations in shifting the kinetic balance to alter gene expression."
Microscope reveals a little splice of life (2/15)
"Using laser scanning fluorescence microscopy, Boise State biophysicist Matt Ferguson is getting a close-up look at what’s happening inside living cells in real time."
Faculty Update (2/15)
"Three months ago, the open-access journal eLife published biophysicist Matthew Ferguson’s paper on the kinetics of RNA synthesis. The day it appeared, Ferguson added the paper’s web link to his profiles on Facebook, LinkedIn, and the academic social network ResearchGate."
Finding Order in Randomness: Single-Molecule Studies Reveal Stochastic RNA Processing (11/14)
"The results of these studies reveal the existence of multiple pathways for intron removal at single molecule resolution in living cells."