Essential Questions:
How does gene regulation relate to the continuity of life?
How is a species’ genetic information diversified from generation to generation?
Unit Learning Objectives for Unit 6 - Gene Expression from the AP® curriculum
By the end of the unit you should be able to...
Students will be able to….
Describe the structures involved in passing hereditary information from one generation to the next.
Describe the characteristics of DNA that allow it to be used as the hereditary material.
Describe the mechanisms by which genetic information is copied for transmission between generations.
Describe the mechanisms by which genetic information flows from DNA to RNA to protein.
Explain how the phenotype of an organism is determined by its genotype.
Describe the types of interactions that regulate gene expression.
Explain how the location of regulatory sequences relates to their function.
Explain how the binding of transcription factors to promoter regions affects gene expression and/or the phenotype of the organism
Explain the connection between the regulation of gene expression and phenotypic differences in cells and organisms.
Describe the various types of mutation.
Explain how changes in genotype may result in changes in phenotype
Explain how alterations in DNA sequences contribute to variation that can be subject to natural selection
Explain the use of genetic engineering techniques in analyzing or manipulating DNA.
Unit 6 Understandings - Knowledge to Understand by the End of the Unit
Learning Outcomes
Describe the properties a substance must possess in order to serve as the genetic material.
Examine how historical researchers demonstrated that DNA was the genetic material.
Explain the chemical structure of DNA as defined by the Watson and Crick model.
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Learning Outcomes
Describe the structure of an operon and state the role of each component of the operon.
Explain how the trp and lac operons of prokaryotes are regulated.
Distinguish between positive and negative regulation of gene expression in prokaryotes.
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Learning Outcomes
List the levels of control of gene expression in eukaryotes.
Summarize how chromatin structure may be involved in regulation of gene expression in eukaryotes.
Identify the mechanisms of transcriptional, posttranscriptional, and translational control of gene expression.
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Learning Outcomes
Distinguish between the sciences of genomics, proteomics, and bioinformatics.
Identify the function of repetitive elements, transposons, and unique noncoding RNA sequences in the human genome.
Explain how DNA microarrays are used in the study of genomics.
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