Unit Learning Objectives for Unit 4 -Cell Communication & Cell Cycle from the AP® curriculum
Describe the ways that cells can communicate with one another.
Explain how cells communicate with one another over short and long distances.
Describe the components of a signal transduction pathway.
Describe the role of components of a signal transduction pathway in producing a cellular response.
Describe the role of the environment in eliciting a cellular response.
Describe the different types of cellular responses elicited by a signal transduction pathway.
Explain how a change in the structure of any signaling molecule affects the activity of the signaling pathway.
Describe positive and/ or negative feedback mechanisms.
Explain how negative feedback helps to maintain homeostasis.
Explain how positive feedback affects homeostasis.
Describe the events that occur in the cell cycle.
Explain how mitosis results in the transmission of chromosomes from one generation to the next.
Describe the role of checkpoints in regulating the cell cycle.
Describe the effects of disruptions to the cell cycle on the cell or organism.
Learning Outcomes
What are the four types of signaling that are found in multicellular organisms?
What are the differences between internal receptors and cell-surface receptors?
What is the relationship between a ligand’s structure and its mechanism of action?
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Learning Outcomes
How does the binding of a ligand initiate signal transduction throughout a cell?
What is the role of second messengers in signal transduction?
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How do signaling pathways direct protein expression, cellular metabolism, and cell growth?
What is the role of apoptosis in the development and maintenance of a healthy organism?
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Learning Outcomes
How do signaling pathways direct protein expression, cellular metabolism, and cell growth?
What is the role of apoptosis in the development and maintenance of a healthy organism?
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Learning Outcomes
Define homeostasis and explain why it is an essential feature of all living organisms.
Evaluate the evolutionary benefits of regulating an internal variable, such as body temperature, versus the cost.
Differentiate between positive and negative feedback mechanisms and list one specific example of each in animals.
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Describe three major functions of the lymphatic system.
Distinguish between the roles of primary and secondary lymphoid tissues and list examples of each.
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Define innate immunity.
Describe four mechanisms of innate immunity and the major tissues, molecules, and/or cells involved.
Explain some specific ways that the innate immune system interacts with and influences the adaptive immune system.
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Compare and contrast the activities of B cells and T cells.
Describe the basic structure of an antibody molecule and explain the different functions of IgG, IgA, IgM, and IgE.
Define monoclonal antibodies and list some specific applications of this technology.
Discuss active and passive immune responses, giving specific examples of each.
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Learning Outcomes
List all the major components of the human digestive tract, from the mouth to the anus.
Compare and contrast the structural features of the small intestine and the large intestine.
Discuss the major functions of the pancreas, liver, and gallbladder.
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Learning Outcomes
List the four stages of interphase, and describe the major events that occur during each stage in preparation for cell division.
Describe the difference between mitosis and cytokinesis.
List the checkpoints that regulate the progression of cells through the cell cycle.
Explain the mechanisms within the G1 cell cycle checkpoint that evaluates growth signals, determine nutrient availability, and assess DNA integrity.
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Learning Outcomes
1. Explain how DNA becomes sufficiently compacted to fit inside a nucleus.
Distinguish between euchromatin and heterochromatin.
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Explain how the cell prepares the chromosomes and centrosomes prior to nuclear division.
Summarize the major events that occur during mitosis and cytokinesis.
Discuss why human stem cells continuously conduct mitosis.
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Learning Outcomes
Describe the basic characteristics of cancer cells.
Distinguish between the roles of the tumor-suppressor genes and protoncogenes in the regulation of the cell cycle.
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