Rainey Lab

Department of Molecular & Integrative Physiology  | University of Michigan

ANNOUNCEMENTS

** CONGRATULATIONS **

to:

Juilee Rege, Ph.D.

Nature Genetics

RECENT PUBLICATIONS

Rege J, Nanba K, Bandulik S, Kosmann C, Blinder AR, Vats P, Kumar-Sinha C, Lerario AM, Else T, Yamazaki Y, Satoh F, Sasano H, Giordano TJ, Williams TA, Reincke M, Turcu AF, Udager AM, Warth R, Rainey WE. Somatic SLC30A1 Mutations Altering Zinc Transporter ZnT1 Cause Aldosterone-Producing Adenomas and Primary Aldosteronism. Nat Genet. 2023 Oct;55(10):1623-1631.  PMID: 37709865

Nanba K, Blinder AR, Udager AM, Hirokawa Y, Miura T, Okuno H, Moriyoshi K, Yamazaki Y, Sasano H, Yasoda A, Satoh-Asahara N, Rainey WE, Tagami T Double somatic mutations in CTNNB1 and GNA11 in an aldosterone-producing adenoma. Front Endocrinol (Lausanne) 2024 Mar 5:15:1286297 PMCID: PMC10948454

Van Rooyen D, Lerario AM, Little DW, Ullenbruch MR, Taylor, MJ, Gomez-Sanchez, CE, Hammer GD, Rainey WE. Chronic activation of adrenal Gq signaling induces Cyp11b2 expression in the zona fasciculata and hyperaldosteronism. Mol Cell Endocrinol 2024 May 1:585:112176. PMID:38341019

van Rooyen D, Bandulik S, Coon G, Laukemper M, Kumar-Sinha C, Udager AM, Lee C, Wachtel H, Cohen DL, Luther JM, Giordano T, Turcu A, Warth R, Rainey WE, Rege J. Somatic Mutations in MCOLN3 in Aldosterone-Producing Adenomas cause Primary Aldosteronism. bioRxiv (Preprint). 2024 Oct 23:2024.10.20.619295. PMCID: PMC11526969


RECENT CONFERENCES

Progress in Primary Aldosteronism (PiPA-8), Munich, Germany Oct 21-22, 2024


ADRENAL JOURNAL CLUB

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Researching Adrenal Physiology and Disease

The Rainey Laboratory is located in the Department of Molecular and Integrative Physiology at the University of Michigan in Ann Arbor, Michigan. Our research focuses on adrenal gland steroid hormone production. Our work takes a "bench-to-patient-bedside" approach to defining the role of the adrenal gland in normal physiology and endocrine diseases.

Our team consists of post-doctoral fellows, graduate students, undergraduate students, and technicians with a variety of scientific interests and international backgrounds. The lab provides a stimulating and enriching environment for conducting research directed at improving the diagnosis and treatment of human disease.

The University of Michigan Adrenal Research Group includes six independent NIH funded laboratories that provide support to study all aspects of adrenal physiology and disease. In addition, our research team has an extensive network of national and international collaborators that share our goal of treating or curing adrenal and ovarian diseases.

Donate to Rainey Laboratory Adrenal Research

Donation Code: 328046