Publications

Yu AI, Zhao L, Eaton KA, Ho S, Chen J, Poe S, Becker J, Gonzalez A, McKinstry D, Hasso M, Mendoza-Castrejon J, Whitfield J, Koumpouras C, Schloss PD, Martens EC, Chen GY. Gut Microbiota Modulate CD8 T Cell Responses to Influence Colitis-Associated Tumorigenesis. Cell Reports. 2020 Apr 7;31(1):107471. doi: 10.1016/j.celrep.2020.03.035. [Abstract]

Seregin SS, Golovchenko N, Schaf B, Chen J, Pudlo NA, Mitchell J, Baxter NT, Zhao L, Schloss PD, Martens EC, Eaton KA, Chen GY. NLRP6 Protects Il10-/- Mice from Colitis by Limiting Colonization of Akkermansia muciniphila. Cell Reports. 2017 Jun 6;19(10):2174. doi: 10.1016/j.celrep.2017.05.074. [Abstract]

Seregin SS, Golovchenko N, Schaf B, Eaton KA, Chen J, Chen GY. NLRP6 function in inflammatory monocytes reduces susceptibility to chemically-induced intestinal injury. Mucosal Immunology. 2017 Mar;10(2):434-445. doi: 10.1038/mi.2016.55. Epub 2016 Jun 29. [Abstract]

Zhan Y^*, Seregin SS*, Chen J, Chen GY. Nod1 Limits Colitis-Associated Tumorigenesis by Regulating IFN-γ Production. J Immunol. 2016 Jun 15;196(12):5121-9. (* - co-first authors). [Abstract]

Zackular JP, Baxter NT, Iverson KD, Sadler WD, Petrosino JF, Chen GY, and Schloss PD. The gut microbiome modulates colon tumorigenesis. MBio. 2013 Nov 5;4(6):e00692-13. [Abstract]

Zhan Y, Chen PJ, Sadler WD, Wang F, Poe S, Nunez G, Eaton KA, and Chen GY. Gut microbiota protects against gastrointestinal tumorigenesis caused by epithelial injury. Cancer Res. 2013 Oct 28. PMID: 24165160 [Abstract]

*Chen GY, Liu M, Wang F, Bertin J, Núñez G. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol. 2011 Jun 15; 186(12):7187-94. Epub 2011 May 4. PMID 21543645, PMC3133458. *Co-corresponding author [Abstract]

*Chen GY, Núñez G. Inflammasomes in intestinal inflammation and cancer. Gastroenterology. 2011 Dec; 141(6):1986-99. Epub 2011 Oct 15. Review. PMID 22005480, PMC3442608. *Co-corresponding author [Abstract]